Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 8/20 | 0.44 |
| ▸ | NPC1 | O15118 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5717731 | 0.77 | HPGD (0.47) | HPGDMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL1163964 | 0.76 | MAPT (0.47) | HPGDMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL4339780 | 0.75 | ALDH1A1 (0.56) | HPGDMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL3867561 | 0.73 | HPGD (0.53) | HPGDMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL7603136 | 0.73 | MTNR1A (0.73) | HPGDRAB9ANPC1ALDH1A1HTT | |
| SCHEMBL2213224 | 0.73 | HPGD (0.56) | HPGDMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL5717752 | 0.72 | NPC1 (0.43) | HPGDMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL6278596 | 0.72 | HPGD (0.55) | HPGDMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL6468979 | 0.71 | FBP1 (0.41) | HPGDMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL2731878 | 0.70 | NPC1 (0.68) | HPGDMAPTRAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1900732-A1 | NOVEL NITROGENATED HETEROCYCLIC COMPOUND AND SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2008-03-19 | — | — | EP | disclosed |