Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diphenylether. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | LTA4H | P09960 | 6/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.48 |
| ▸ | BAX | Q07812 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylether SCHEMBL28593325 | 0.98 | LMNA (0.55) | LMNALTA4HTSHRNPY5RNR1H2 | |
| Diphenylether SCHEMBL8049569 | 0.96 | LMNA (0.53) | LMNALTA4HTSHRNPY5RNR1H2 | |
| Diphenylether SCHEMBL896711 | 0.92 | NPY5R (0.51) | LMNALTA4HTSHRNPY5RPTGS1 | |
| Diphenylether SCHEMBL7865304 | 0.89 | LMNA (0.47) | LMNALTA4HTSHRNPY5RNR1H2 | |
| Diphenylether SCHEMBL6560849 | 0.89 | NPY5R (0.49) | LMNALTA4HNPY5RPTGS1TDP1 | |
| Diphenylether SCHEMBL3797141 | 0.87 | LTA4H (0.47) | LMNALTA4HTSHRNPY5RNR1H2 | |
| Diphenylether SCHEMBL23494789 | 0.86 | TGM2 (0.47) | LMNALTA4HNPY5RPTGS1TDP1 | |
| Diphenylether SCHEMBL11134302 | 0.85 | LTA4H (0.67) | LMNALTA4HTSHRNPY5RNR1H2 | |
| Diphenylether SCHEMBL29076650 | 0.85 | LTA4H (0.67) | LMNALTA4HTSHRNPY5RNR1H2 | |
| Diphenylether SCHEMBL22367728 | 0.85 | LMNA (0.52) | LMNALTA4HTSHRNPY5RNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 10377 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122079740-A | Efficient composite solubilizer for preparing sec-butyl alcohol by hydration of butylene | — | 2026-05-26 | — | — | CN | claimed |
| CN-122060355-A | Coating with covering and thermal-changing characteristics, thermosensitive color-developing material, preparation process and application | 山东世纪阳光纸业集团有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122060371-A | Preparation method of ultrathin water-based resin coating | 广东瑞和新材料有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122060381-A | Graphene-based anticorrosive paint | 宁德师范学院 | 2026-05-19 | — | — | CN | claimed |
| CN-122037649-A | Composite type alkyne diol wetting dispersant and preparation method thereof | 重庆消烦多新材料有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-122037634-A | Preparation method of marine polymer cement-based hydrophobic coating | 济南大学 | 2026-05-15 | — | — | CN | claimed |
| CN-122037939-A | Etching composition | 宁波安集微电子科技有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-122011948-A | Pressureless sintering silver colloid, preparation method thereof and semiconductor device | 深圳芯源新材料有限公司 | 2026-05-12 | — | — | CN | claimed |
| EP-4377404-B1 | FLUORINE FREE SURFACTANTS AND FOAM COMPOSITIONS | KASOWSKI ROBERT VALENTINE (US) | 2026-05-06 | — | — | EP | claimed |
| US-20260083659-A1 | SUNSCREEN COMPOSITIONS AND METHODS OF USE | MARY KAY INC. (US) | 2026-03-26 | — | — | US | claimed |
| US-5132038-A | Anionic surfactants containing sulfonate diphenyl ether | MACDERMID, INCORPORATED (US) | 1992-07-21 | — | — | US | claimed |
| EP-0436539-B1 | FACING ELEMENT WITH CORRESPONDING ADHESIVE MORTAR | THÖNE, Gerd (DE) | 1992-07-01 | — | — | EP | claimed |
| US-5126193-A | Ink jet recording sheet | EASTMAN KODAK COMPANY (US) | 1992-06-30 | — | — | US | claimed |
| US-5032427-A | Pretreatment with organic liquid | MACDERMID, INCORPORATED (US) | 1991-07-16 | — | — | US | claimed |
| WO-1990015441-A1 | LASER DYE LIQUIDS, LASER DYE INSTRUMENTS AND METHODS | EXCITON INCORPORATED (US) | 1990-12-13 | — | — | WO | claimed |
| US-4896329-A | Laser dye liquids, laser dye instruments and methods | EXCITON INCORPORATED (US) | 1990-01-23 | — | — | US | claimed |
| EP-0143327-B1 | METHOD AND COMPOSITIONS FOR REMOVAL OF UNDESIRABLE ORGANIC MATTER | AMERICAN CYANAMID COMPANY (US) | 1988-06-01 | — | — | EP | claimed |
| EP-0143327-A2 | Method and compositions for removal of undesirable organic matter | AMERICAN CYANAMID COMPANY (US) | 1985-06-05 | — | — | EP | claimed |
| US-4477288-A | APPLYING IMIDAZOLE OR PYRAZOLE COMPOUND AND A PHENYL GLYCOL ETHER | AMERICAN CYANAMID COMPANY (US) | 1984-10-16 | — | — | US | claimed |
| US-4413148-A | REACTION OF CUMENE HYDROPEROXIDE AND DIMETHYLBENZYLMLCOHOL | NIPPON OIL AND FATS CO., LTD. (JP) | 1983-11-01 | — | — | US | claimed |