SCHEMBL5048773

SCHEMBL5048773

Cc1ccc(-c2ccc(F)cc2F)cc1C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 4/20 0.47
TTR P02766 2/20 0.47
KDM4E B2RXH2 1/20 0.47
MEN1 O00255 1/20 0.47
USP2 O75604 1/20 0.47
ALDH1A1 P00352 1/20 0.47
DHFR P00374 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
LMNA P02545 1/20 0.47
ALB P02768 1/20 0.47
HMGB1 P09429 1/20 0.47
HPGD P15428 1/20 0.47
CXCL12 P48061 1/20 0.47
KMT2A Q03164 1/20 0.47
HIF1A Q16665 1/20 0.47
SLC22A6 Q4U2R8 1/20 0.47
ACMSD Q8TDX5 1/20 0.47
HSD17B10 Q99714 1/20 0.47
PTGS1 P23219 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26974251 0.88 AKR1C3 (0.54) TTRKDM4EMEN1USP2ALDH1A1
SCHEMBL19912967 0.88 PTGS2 (0.50) PTGS2PTGS1AKR1C3AKR1C2AKR1B10
SCHEMBL16945883 0.86 PTGS2 (0.46) PTGS2PTGS1AKR1C3AKR1C2AKR1B10
SCHEMBL10304724 0.84 PTGS2 (0.47) PTGS2PTGS1ABL1
SCHEMBL27115962 0.84 PTGS2 (0.47) PTGS2PTGS1AKR1C3AKR1C2AKR1B10
SCHEMBL16728066 0.83 PTGS2 (0.51) PTGS2TTRKDM4EMEN1USP2
SCHEMBL2760398 0.83 TTR (0.59) TTRKDM4EMEN1USP2ALDH1A1
SCHEMBL13368889 0.83 TTR (0.48) PTGS2TTRKDM4EMEN1USP2
SCHEMBL802682 0.82 PTGS2 (0.46) PTGS2PTGS1AKR1C3AKR1C2AKR1B10
SCHEMBL25840018 0.81 PTGS2 (0.51) PTGS2ALDH1A1PTGS1AKR1C3AKR1C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2182002-B1 Novel compounds for electronic material and organic electronic device using the same GRACEL DISPLAY INC (KR) 2012-07-04 EP disclosed
EP-2066150-B1 Novel red electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC (KR) 2010-05-26 EP disclosed
EP-2182002-A1 Novel compounds for electronic material and organic electronic device using the same Gracel Display Inc. (KR) 2010-05-05 EP disclosed
US-20100102710-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-04-29 US disclosed
US-20090261714-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-10-22 US disclosed
EP-2098532-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same Gracel Display Inc. (KR) 2009-09-09 EP disclosed
EP-2085450-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same Gracel Display Inc. (KR) 2009-08-05 EP disclosed
US-20090184629-A1 Novel red electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-07-23 US disclosed
US-20090179555-A1 Novel red electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-07-16 US disclosed
US-20090174316-A1 Novel red electroluminescent compounds and organi electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-07-09 US disclosed
US-20090153037-A1 Novel red electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-06-18 US disclosed
EP-2062959-A2 Novel red electroluminescent compounds and organic electroluminescent device using the same Gracel Display Inc. (KR) 2009-05-27 EP disclosed
EP-2055710-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same Gracel Display Inc. (KR) 2009-05-06 EP disclosed
EP-2053112-A2 Novel red electroluminescent compounds and organic electroluminescent device using the same Gracel Display Inc. (KR) 2009-04-29 EP disclosed
EP-1986633-A2 TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY Summit Corporation Plc (GB) 2008-11-05 EP disclosed
WO-2007091106-A2 TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY SUMMIT CORPORATION PLC (GB) 2007-08-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090261714-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same AOX1, ODC1, LEF1 PTGS2 1889/4885TTR 3736/4885KDM4E 2044/4885
US-20090174316-A1 Novel red electroluminescent compounds and organi electroluminescent device using the same ALPI, IK, ALDH1A2 PTGS2 3102/4885TTR 3437/4885KDM4E 2833/4885
US-20090153037-A1 Novel red electroluminescent compounds and organic electroluminescent device using the same NDUFS2, ALDH1A2, ODC1 PTGS2 2276/4885TTR 3448/4885KDM4E 1792/4885
US-20090184629-A1 Novel red electroluminescent compounds and organic electroluminescent device using the same IK, TYR, EYA2 PTGS2 3970/4885TTR 2099/4885KDM4E 1716/4885
US-20100102710-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same ODC1, AOX1, OR10J3 PTGS2 2068/4885TTR 3305/4885KDM4E 1974/4885
US-20090179555-A1 Novel red electroluminescent compounds and organic electroluminescent device using the same NDUFS2, ALDH1A2, ODC1 PTGS2 2276/4885TTR 3448/4885KDM4E 1792/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.