Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.49 |
| ▸ | MTOR | P42345 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.49 |
| ▸ | DRD2 | P14416 | 3/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5050780 | 0.83 | ADRB2 (0.51) | MAPTTDP1ADRB2KDM4EHSD17B10 | |
| SCHEMBL7544277 | 0.80 | MAPT (0.53) | MAPTTDP1ADRB2KDM4EHSD17B10 | |
| SCHEMBL7764700 | 0.80 | MAPT (0.53) | MAPTTDP1ADRB2KDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL6394648 | 0.79 | KDM4E (0.54) | MAPTTDP1ADRB2KDM4EHSD17B10 | |
| SCHEMBL4989891 | 0.75 | TDP1 (0.50) | MAPTTDP1ADRB2KDM4EHSD17B10 | |
| SCHEMBL21295303 | 0.73 | KDM4E (0.46) | MAPTTDP1ADRB2KDM4EHSD17B10 | |
| SCHEMBL27153216 | 0.73 | HDAC6 (0.43) | MAPTMAPK1ALDH1A1SLC6A2 | |
| SCHEMBL25645952 | 0.72 | ALDH1A1 (0.45) | ADRB2KDM4EADRB1DRD2ALDH1A1 | |
| SCHEMBL8285875 | 0.72 | ALDH1A1 (0.47) | MAPTHSD17B10KMT2ATSHRCYP3A4 | |
| SCHEMBL4578363 | 0.72 | ALDH1A1 (0.47) | MAPTHSD17B10KMT2ATSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110060045-A1 | ANTI-DIABETIC CATARACT COMPOUNDS AND THEIR USES | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2011-03-10 | — | — | US | claimed |
| EP-2001833-A1 | ANTI-DIABETIC CATARACT COMPOUNDS AND THEIR USES | National Research Council of Canada (CA) | 2008-12-17 | — | — | EP | claimed |
| WO-2007109882-A1 | ANTI-DIABETIC CATARACT COMPOUNDS AND THEIR USES | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2007-10-04 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110060045-A1 | ANTI-DIABETIC CATARACT COMPOUNDS AND THEIR USES | INSR, GPR119, ADRB1 | MAPT 3973/4885TDP1 3959/4885ADRB2 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.