Sugi Predict

Sugi Predict / Compounds / SCHEMBL505093

SCHEMBL505093

SCHEMBL505093

Cc1ccc(S(=O)(=O)N2CCC(=O)CC2)cc1

nearest known ligand 0.69

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 5/20 0.69
▸ PKM P14618 3/20 0.68
▸ HTT P42858 2/20 0.68
▸ ALDH1A1 P00352 1/20 0.68
▸ POLB P06746 1/20 0.68
▸ MEN1 O00255 3/20 0.62
▸ GAA P10253 2/20 0.60
▸ LMNA P02545 2/20 0.60
▸ SMN1; SMN2 Q16637 1/20 0.60
▸ HSD11B1 P28845 1/20 0.57
▸ TSHR P16473 1/20 0.57
▸ CYP2C19 P33261 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8024905 0.92 KMT2A (0.64) KMT2APKMHTTALDH1A1POLB
SCHEMBL265611 0.89 PKM (0.61) KMT2APKMHTTALDH1A1POLB
SCHEMBL3971438 0.86 PKM (0.88) KMT2APKMHTTALDH1A1POLB
SCHEMBL699639 0.86 PKM (0.88) KMT2APKMHTTALDH1A1POLB
SCHEMBL3303527 0.86 PKM (0.88) KMT2APKMHTTALDH1A1POLB
SCHEMBL4537086 0.86 PKM (0.88) KMT2APKMHTTALDH1A1POLB
SCHEMBL8203532 0.86 PKM (0.88) KMT2APKMHTTALDH1A1POLB
SCHEMBL10724066 0.86 PKM (0.88) KMT2APKMHTTALDH1A1POLB
SCHEMBL565301 0.86 PKM (0.88) KMT2APKMHTTALDH1A1POLB
SCHEMBL8200466 0.86 PKM (0.88) KMT2APKMHTTALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120018406-A Fine circuit pattern diffusion inhibitor and preparation method and application method thereof 深圳市板明科技股份有限公司 2025-05-16 — — CN claimed
CN-120018406-A Fine circuit pattern diffusion inhibitor and preparation method and application method thereof 深圳市板明科技股份有限公司 2025-05-16 — — CN disclosed
US-20250059200-A1 PROCESS FOR C-H INSERTION BY GEM-HYDROGENATION OF AN INTERNAL ALKYNE STUDIENGESELLSCHAFT KOHLE GGMBH (DE) 2025-02-20 — — US disclosed
EP-4413012-A1 PROCESS FOR C-H INSERTION BY GEM-HYDROGENATION OF AN INTERNAL ALKYNE Studiengesellschaft Kohle gGmbH (DE) 2024-08-14 — — EP disclosed
WO-2023110394-A1 PROCESS FOR C-H INSERTION BY GEM-HYDROGENATION OF AN INTERNAL ALKYNE STUDIENGESELLSCHAFT KOHLE GGMBH (DE) 2023-06-22 — — WO disclosed
EP-4198038-A1 PROCESS FOR C-H INSERTION BY GEM-HYDROGENATION OF AN INTERNAL ALKYNE Studiengesellschaft Kohle mbH (DE) 2023-06-21 — — EP disclosed
CN-112479984-B Method for synthesizing enol trifluoromethanesulfonate 湖北航天化学技术研究所 2022-12-13 — — CN disclosed
CN-112479984-A Method for synthesizing enol trifluoromethanesulfonate 湖北航天化学技术研究所 2021-03-12 — — CN disclosed
US-20190023716-A1 FUMAGILLOL SPIROCYCLIC COMPOUNDS AND FUSED BICYCLIC COMPOUNDS AND METHODS OF MAKING AND USING SAME ZAFGEN INC (US) 2019-01-24 — — US disclosed
US-9944613-B2 Fumagillol spirocyclic compounds and fused bicyclic compounds and methods of making and using same ZAFGEN, INC. (US) 2018-04-17 — — US disclosed
EP-1414813-A1 1,2,4-TRIOXOLANE ANTIMALARIALS Medicines for Malaria Venture (CH) 2004-05-06 — — EP disclosed
EP-1401840-A1 NOVEL 4-AMINO-5,6-SUBSTITUTED THIOPHENO 2,3-D]PYRIMIDINES Bayer Corporation (US) 2004-03-31 — — EP disclosed
US-20030144328-A1 Compounds which inhibit leukocyte adhesion mediated by VLA-4 KONRADI ANDREI W (US) 2003-07-31 — — US disclosed
US-20030119829-A1 4-amino-5,6-substituted thiopheno [2,3-d] pyrimidines, pharmaceutical compositions containing the same, and their use in the treatment or prevention of PDE7B-mediated diseases and conditions BAYER INTELLECTUAL PROPERTY GMBH (DE) 2003-06-26 — — US disclosed
WO-2003000676-A1 1,2,4-TRIOXOLANE ANTIMALARIALS MEDICINES FOR MALARIA VENTURE (CH) 2003-01-03 — — WO disclosed
US-6486199-B1 Spiro and dispiro 1,2,4-trioxolane antimalarials MEDICINES FOR MALARIA VENTURE MMV INTERNATIONAL CENTRE COINTRIN (CH) 2002-11-26 — — US disclosed
US-6479492-B1 TREATMENT OF INFLAMMATORY DISEASES IN A MAMMALIAN PATIENT ELAN PHARMACEUTICALS, INC. 2002-11-12 — — US disclosed
WO-2002088138-A1 NOVEL 4-AMINO-5,6-SUBSTITUTED THIOPHENO[2,3-D]PYRIMIDINES BAYER CORPORATION (US) 2002-11-07 — — WO disclosed
EP-1144384-A1 COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 Elan Pharmaceuticals, Inc. (US) 2001-10-17 — — EP disclosed
WO-2000043369-A1 COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 ELAN PHARMACEUTICALS, INC. (US) 2000-07-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250059200-A1 PROCESS FOR C-H INSERTION BY GEM-HYDROGENATION OF AN INTERNAL ALKYNE GGH, GEMIN4, GMNN KMT2A 2112/4885PKM 3532/4885HTT 943/4885
US-20030144328-A1 Compounds which inhibit leukocyte adhesion mediated by VLA-4 VCAM1, ICAM1, CD4 KMT2A 1871/4885PKM 3448/4885HTT 3592/4885
US-20030119829-A1 4-amino-5,6-substituted thiopheno [2,3-d] pyrimidines, pharmaceutical compositions containing the same, and their use in the treatment or prevention of PDE7B-mediated diseases and conditions PDE7B, PDE4B, PDE7A KMT2A 2143/4885PKM 832/4885HTT 4454/4885
US-20190023716-A1 FUMAGILLOL SPIROCYCLIC COMPOUNDS AND FUSED BICYCLIC COMPOUNDS AND METHODS OF MAKING AND USING SAME METAP2, FOLH1, FAP KMT2A 1929/4885PKM 1588/4885HTT 1421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.