Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | GSK3B | P49841 | 1/20 | 0.62 |
| ▸ | MMP1 | P03956 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 4/20 | 0.60 |
| ▸ | THRA | P10827 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.58 |
| ▸ | RARB | P10826 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.55 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.55 |
| ▸ | DRD4 | P21917 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2356907 | 0.97 | TP53 (0.66) | L3MBTL1GSK3BMMP1THRBTHRA | |
| SCHEMBL7861984 | 0.95 | TP53 (0.69) | L3MBTL1GSK3BTHRBTHRATP53 | |
| SCHEMBL14644865 | 0.95 | TP53 (0.69) | L3MBTL1GSK3BTHRBTHRATP53 | |
| SCHEMBL7861703 | 0.95 | TP53 (0.69) | L3MBTL1GSK3BTHRBTHRATP53 | |
| SCHEMBL8591116 | 0.95 | TP53 (0.69) | L3MBTL1GSK3BTHRBTHRATP53 | |
| SCHEMBL4629110 | 0.95 | TP53 (0.69) | L3MBTL1GSK3BTHRBTHRATP53 | |
| SCHEMBL1437711 | 0.95 | TP53 (0.69) | L3MBTL1GSK3BTHRBTHRATP53 | |
| SCHEMBL5057170 | 0.93 | L3MBTL1 (0.70) | L3MBTL1GSK3BMMP1THRBTHRA | |
| SCHEMBL7371927 | 0.92 | RARB (0.68) | L3MBTL1GSK3BMMP1THRBTHRA | |
| SCHEMBL8673568 | 0.89 | PLA2G4B (0.55) | L3MBTL1GSK3BMMP1THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3976656-A | 1,4-Bis(5-p-n-butoxyphenyloxazol-2-yl)benzene and the preparaion thereof | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1976-08-24 | — | — | US | claimed |
| US-12024519-B2 | Fused ring derivative having MGAT-2 inhibitory activity | SHIONOGI & CO., LTD. (JP) | 2024-07-02 | — | — | US | disclosed |
| US-20160166560-A1 | Urea Compounds and Their Use as FAAH Enzyme Inhibitors | BIAL-PORTELA & CA, S.A. (PT) | 2016-06-16 | — | — | US | disclosed |
| US-20150344467-A1 | 5- AND 6-MEMBERED HETEROCYCLIC COMPOUNDS | FMR LLC | 2015-12-03 | — | — | US | disclosed |
| WO-2015016728-A1 | UREA COMPOUNDS AND THEIR USE AS FAAH ENZYME INHIBITORS | BIAL - PORTELA & Cª, S.A. (PT) | 2015-02-05 | — | — | WO | disclosed |
| US-20140038965-A1 | 5- AND 6-MEMBERED HETEROCYCLIC COMPOUNDS | ENVIVO PHARMACEUTICALS, INC. (US) | 2014-02-06 | — | — | US | disclosed |
| US-8481534-B2 | 5- and 6-membered heterocyclic compounds | ENVIVO PHARMACEUTICALS, INC. (US) | 2013-07-09 | — | — | US | disclosed |
| US-8277777-B2 | Compound having affinity for amyloid | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2012-10-02 | — | — | US | disclosed |
| US-20110183976-A1 | 5- AND 6-MEMBERED HETEROCYCLIC COMPOUNDS | FMR LLC | 2011-07-28 | — | — | US | disclosed |
| US-20100092387-A1 | Novel Compound Having Affinity For Amyloid | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2010-04-15 | — | — | US | disclosed |
| EP-0736509-B1 | Processes for preparing optically active alcohols and optically active amines | SUMITOMO CHEMICAL CO (JP) | 2001-11-14 | — | — | EP | disclosed |
| US-6156940-A | Process for producing optically active carbinols | SUMIKA FINE CHEMICALS COMPANY, LIMITED (JP) | 2000-12-05 | — | — | US | disclosed |
| US-6025531-A | REACTING A PROCHIRAL KETONE WITH A MIXTURE BORON-CONTAINING COMPOUNDS HAVING A BORANE REACTION PRODUCT FROM OPTICALLY ACTIVE BETA-AMINOALCOHOL AND A BORON HYDRIDE OR A METAL BOROHYDRIDE, AND AN OPTICALLY ACTIVE OXAZABOROLIDINE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-15 | — | — | US | disclosed |
| EP-0713848-B1 | Process for producing optically active carbinols | SUMIKA FINE CHEMICALS COMPANY (JP) | 1999-09-08 | — | — | EP | disclosed |
| US-5831132-A | REDUCING AGENT FROM BORANES AND AMINO ALCOHOLS | SUMIKA FINE CHEMICALS COMPANY, LTD. (JP) | 1998-11-03 | — | — | US | disclosed |
| US-5801280-A | Processes for preparing optically active alcohols and optically active amines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-09-01 | — | — | US | disclosed |
| EP-0736509-A2 | Processes for preparing optically active alcohols and optically active amines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-10-09 | — | — | EP | disclosed |
| EP-0713848-A1 | Process for producing optically active carbinols | SUMIKA FINE CHEMICALS Company, Limited (JP) | 1996-05-29 | — | — | EP | disclosed |
| US-4033978-A | Thiacycl[2.2.2]azine carboxylic acids | SYNTEX (U.S.A.) INC. (US) | 1977-07-05 | — | — | US | disclosed |
| US-3976656-A | 1,4-Bis(5-p-n-butoxyphenyloxazol-2-yl)benzene and the preparaion thereof | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1976-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150344467-A1 | 5- AND 6-MEMBERED HETEROCYCLIC COMPOUNDS | PDE7A, ACHE, PDE5A | L3MBTL1 2697/4885GSK3B 905/4885MMP1 1288/4885 |
| US-20160166560-A1 | Urea Compounds and Their Use as FAAH Enzyme Inhibitors | FAAH, FAAH2, HRH2 | L3MBTL1 4173/4885GSK3B 4753/4885MMP1 1408/4885 |
| US-20140038965-A1 | 5- AND 6-MEMBERED HETEROCYCLIC COMPOUNDS | PDE7A, ACHE, PDE5A | L3MBTL1 2697/4885GSK3B 905/4885MMP1 1288/4885 |
| US-20110183976-A1 | 5- AND 6-MEMBERED HETEROCYCLIC COMPOUNDS | ACHE, PDE7A, PDE5A | L3MBTL1 2678/4885GSK3B 934/4885MMP1 1331/4885 |
| US-20100092387-A1 | Novel Compound Having Affinity For Amyloid | APP, SLC43A1, APBA1 | L3MBTL1 395/4885GSK3B 3265/4885MMP1 2918/4885 |
| US-12024519-B2 | Fused ring derivative having MGAT-2 inhibitory activity | MGAT2, MGAT1, ACAT2 | L3MBTL1 704/4885GSK3B 1437/4885MMP1 4169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.