SCHEMBL50615

SCHEMBL50615

[CH2][C@H]1O[C@@H](n2cnc3c(N)ncnc32)C[C@@H]1O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ AHCY P23526 8/20 0.59
▸ ADA P00813 1/20 0.55
▸ STING1 Q86WV6 1/20 0.55
▸ TP53 P04637 1/20 0.54
▸ CYP2C9 P11712 1/20 0.54
▸ NFKB1 P19838 1/20 0.54
▸ MAPK1 P28482 1/20 0.54
▸ HSD17B10 Q99714 1/20 0.54
▸ MEN1 O00255 1/20 0.54
▸ ALDH1A1 P00352 1/20 0.54
▸ APEX1 P27695 1/20 0.54
▸ PI4KA P42356 1/20 0.54
▸ BLM P54132 1/20 0.54
▸ KMT2A Q03164 1/20 0.54
▸ ADCY1 Q08828 1/20 0.54
▸ PI4K2B Q8TCG2 1/20 0.54
▸ PI4K2A Q9BTU6 1/20 0.54
▸ PI4KB Q9UBF8 1/20 0.54
▸ POLB P06746 1/20 0.54
▸ ENPP1 P22413 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17833855 0.87 AHCY (0.62) AHCYADASTING1TP53CYP2C9
SCHEMBL6575705 0.86 HIF1A (0.50) AHCYPOLBADORA3
SCHEMBL896624 0.85 AHCY (0.59) AHCYADASTING1TP53CYP2C9
SCHEMBL29362124 0.85 AHCY (0.59) AHCYADASTING1TP53CYP2C9
SCHEMBL5962596 0.85 AHCY (0.59) AHCYADASTING1TP53CYP2C9
SCHEMBL23396436 0.85 AHCY (0.59) AHCYADASTING1TP53CYP2C9
SCHEMBL5962598 0.85 AHCY (0.59) AHCYADASTING1TP53CYP2C9
SCHEMBL284737 0.85 AHCY (0.59) AHCYADASTING1TP53CYP2C9
SCHEMBL20794222 0.85 AHCY (0.59) AHCYADASTING1TP53CYP2C9
SCHEMBL10015774 0.85 AHCY (0.59) AHCYADASTING1TP53CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 492 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240101591-A1 NOVEL, HEAVY VITAMIN B12 DERIVATIVES CHARLES STURT UNIVERSITY (AU) 2024-03-28 — — US claimed
US-11884695-B2 Heavy vitamin B12 derivatives CHARLES STURT UNIVERSITY (AU) 2024-01-30 — — US claimed
US-20230183287-A1 NOVEL, HEAVY VITAMIN B12 DERIVATIVES CHARLES STURT UNIVERSITY (AU) 2023-06-15 — — US claimed
EP-4168009-A1 CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS Hangzhou DAC Biotech Co., Ltd. (CN) 2023-04-26 — — EP claimed
US-11597747-B2 Heavy vitamin B12 derivatives CHARLES STURT UNIVERSITY (AU) 2023-03-07 — — US claimed
US-20230010108-A1 A CONJUGATION LINKER CONTAINING 2,3-DIAMINOSUCCINYL GROUP HANGZHOU DAC BIOTECH CO., LTD. (CN) 2023-01-12 — — US claimed
EP-3917576-A1 A CONJUGATE OF AN AMANITA TOXIN WITH BRANCHED LINKERS Hangzhou Dac Biotech Co., Ltd. (CN) 2021-12-08 — — EP claimed
WO-2021212638-A1 CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2021-10-28 — — WO claimed
US-20210308277-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2021-10-07 — — US claimed
US-11129910-B2 Specific conjugation linkers, specific immunoconjugates thereof, methods of making and uses such conjugates thereof HANGZHOU DAC BIOTECH CO., LTD. (CN) 2021-09-28 — — US claimed
EP-1066292-B1 METALLOCORRINOIDS AS BIOLOGICALLY COMPATIBLE CARRIERS OF PHARMACOLOGICAL AGENTS UNIV AKRON (US) 2003-03-26 — — EP claimed
US-20020142414-A1 Process for the preparation of protease inhibitors UCP GEN-PHARMA AG (CH) 2002-10-03 — — US claimed
US-20020035087-A1 B complex vitamin compositions that protect against cellular damage caused by ultraviolet light BARCLAY BARRY J (CA) 2002-03-21 — — US claimed
WO-2002003942-A2 B COMPLEX VITAMIN COMPOSITIONS THAT PROTECT AGAINST CELLULAR DAMAGE CAUSED BY ULTRAVIOLET LIGHT PLANET BIOTECH INC. (CA) 2002-01-17 — — WO claimed
EP-1066292-A4 METALLOCORRINOIDS AS BIOLOGICALLY COMPATIBLE CARRIERS OF PHARMACOLOGICAL AGENTS UNIV AKRON (US) 2001-08-16 — — EP claimed
WO-2001014401-A1 NUCLEOSIDE PYROPHOSPHATE AND TRIPHOSPHATE ANALOGS AND RELATED COMPOUNDS AS THERAPEUTIC AGENTS SRI INTERNATIONAL (US) 2001-03-01 — — WO claimed
EP-1066292-A1 METALLOCORRINOIDS AS BIOLOGICALLY COMPATIBLE CARRIERS OF PHARMACOLOGICAL AGENTS The University of Akron (US) 2001-01-10 — — EP claimed
US-5936082-A Metallocorrinoids as biologically compatible carriers of pharmacological agents THE UNIVERSITY OF AKRON (US) 1999-08-10 — — US claimed
WO-1999033833-A1 METALLOCORRINOIDS AS BIOLOGICALLY COMPATIBLE CARRIERS OF PHARMACOLOGICAL AGENTS THE UNIVERSITY OF AKRON (US) 1999-07-08 — — WO claimed
EP-0146785-A1 Process for the preparation of protease inhibitors CIBA-GEIGY AG (CH) 1985-07-03 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020142414-A1 Process for the preparation of protease inhibitors EGLN2, EGLN1, PREP AHCY 1509/4885ADA 2502/4885STING1 453/4885
US-20230010108-A1 A CONJUGATION LINKER CONTAINING 2,3-DIAMINOSUCCINYL GROUP DAO, DDO, DCLRE1A AHCY 963/4885ADA 2072/4885STING1 4724/4885
US-11129910-B2 Specific conjugation linkers, specific immunoconjugates thereof, methods of making and uses such conjugates thereof SLC25A1, GCDH, FH AHCY 1556/4885ADA 3815/4885STING1 3524/4885
US-20230183287-A1 NOVEL, HEAVY VITAMIN B12 DERIVATIVES HMBS, SLC19A1, SLC19A2 AHCY 21/4885ADA 620/4885STING1 4379/4885
US-20240101591-A1 NOVEL, HEAVY VITAMIN B12 DERIVATIVES HMBS, SLC19A1, SLC19A2 AHCY 21/4885ADA 620/4885STING1 4379/4885
US-20020035087-A1 B complex vitamin compositions that protect against cellular damage caused by ultraviolet light MAOB, S100A9, CCNB3 AHCY 346/4885ADA 436/4885STING1 803/4885
US-11884695-B2 Heavy vitamin B12 derivatives HMBS, SLC19A1, SLC19A2 AHCY 44/4885ADA 629/4885STING1 4493/4885
US-20210308277-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS CD2BP2, DCLRE1A, EPCAM AHCY 1802/4885ADA 3917/4885STING1 4850/4885
US-11597747-B2 Heavy vitamin B12 derivatives HMBS, SLC19A1, SLC19A2 AHCY 44/4885ADA 629/4885STING1 4493/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback