Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6050861 | 0.66 | — | — | |
| SCHEMBL26224303 | 0.65 | GABRG2 (0.39) | HTR2CDHODH | |
| SCHEMBL3704382 | 0.65 | HTR2C (0.38) | HTR2CHTR2ADHODH | |
| SCHEMBL30792004 | 0.64 | GOT1 (0.46) | HTR2CHTR2ADHODH | |
| SCHEMBL1456807 | 0.64 | GOT1 (0.46) | HTR2CHTR2ADHODH | |
| SCHEMBL29442588 | 0.64 | GOT1 (0.46) | HTR2CHTR2ADHODH | |
| Hydrochloric Acid SCHEMBL8425421 | 0.64 | HTR2C (0.37) | HTR2CHTR2ADHODH | |
| SCHEMBL20472405 | 0.62 | CNR2 (0.47) | — | |
| Hydrochloric Acid SCHEMBL10877717 | 0.62 | HTR2C (0.36) | HTR2CHTR2ADHODH | |
| SCHEMBL3644361 | 0.62 | HTR2C (0.64) | HTR2CHTR2ADHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080200468-A1 | 2-Substituted 5-Membered Heteroaryl Carboxylates as Hm74a Receptor Agonists | SMITHKLINE BEECHAM CORPORATION | 2008-08-21 | — | — | US | disclosed |
| EP-1853579-A2 | 2-SUBSTITUTED 5-MEMBERED HETEROARYL CARBOXYLATES AS HM74A RECEPTOR AGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-11-14 | — | — | EP | disclosed |
| WO-2006085113-A2 | 2-SUBSTITUTED 5-MEMBERED HETEROARYL CARBOXYLATES AS HM74A RECEPTOR AGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-08-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200468-A1 | 2-Substituted 5-Membered Heteroaryl Carboxylates as Hm74a Receptor Agonists | GPR84, GPR88, HCAR1 | HTR2C 92/4885HTR2A 34/4885DHODH 3139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.