Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.65 |
| ▸ | MPO | P05164 | 7/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.48 |
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1973303 | 0.86 | MPO (0.74) | GPR84MPOSLC6A4RIPK1PCSK9 | |
| SCHEMBL5694492 | 0.85 | TDP1 (0.53) | GPR84MPOTSHRALDH1A1LMNA | |
| SCHEMBL30873950 | 0.84 | MPO (0.76) | GPR84MPOSLC6A4RIPK1PCSK9 | |
| SCHEMBL21396194 | 0.84 | MPO (0.76) | GPR84MPOSLC6A4RIPK1PCSK9 | |
| SCHEMBL17102847 | 0.83 | ALDH1A1 (0.59) | GPR84MPOTSHRALDH1A1LMNA | |
| SCHEMBL5058671 | 0.82 | ALDH1A1 (0.46) | GPR84MPOTSHRALDH1A1LMNA | |
| SCHEMBL6131640 | 0.81 | ALDH1A1 (0.57) | TSHRALDH1A1LMNATDP1GLA | |
| SCHEMBL6284097 | 0.81 | HTR2A (0.58) | TSHRPCSK9ALDH1A1LMNATDP1 | |
| SCHEMBL5058656 | 0.81 | ALDH1A1 (0.45) | GPR84MPOTSHRALDH1A1LMNA | |
| SCHEMBL6516641 | 0.81 | HTR2A (0.58) | SLC6A4TSHRRIPK1PCSK9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007127923-A2 | PLANT GROWTH HORMONE REGULATED TRANSCRIPTION FACTORS AND PROMOTERS THEREOF | DONALD DANFORTH PLANT SCIENCE CENTER (US) | 2007-11-08 | — | — | WO | claimed |
| US-20050107258-A1 | Auxinic analogues of indole-3-acetic acid | Life Technologies Corporation | 2005-05-19 | — | — | US | claimed |
| US-6815205-B2 | GENERATING PLANT ROOTS | INVITROGEN CORPORATION | 2004-11-09 | — | — | US | claimed |
| US-20030087762-A1 | Auxinic analogues of indole-3-acetic acid | LIFE TECHNOLOGIES, INC. | 2003-05-08 | — | — | US | claimed |
| US-6361999-B1 | AMELIORATING DETRIMENTAL EFFECTS OF STRESS ON A PLANT OR PLANT TISSUE, SUCH AS ENVIRONMENTAL STRESS, PHYSICAL STRESS, CHEMICAL STRESS, FROM POLLUTION, CONTAMINATION, DROUGHT, AND LIGHT BY CONTACTING WITH AUXINIC INDOLE ACETIC ACID COMPOUND | LIFE TECHNOLOGIES, INC. | 2002-03-26 | — | — | US | claimed |
| EP-0866850-A4 | AUXINIC ANALOGUES OF INDOLE-3-ACETIC ACID | LIFE TECHNOLOGIES INC (US) | 2000-11-22 | — | — | EP | claimed |
| EP-0866850-A1 | AUXINIC ANALOGUES OF INDOLE-3-ACETIC ACID | LIFE TECHNOLOGIES, INC. (US) | 1998-09-30 | — | — | EP | claimed |
| WO-1997020034-A9 | AUXINIC ANALOGUES OF INDOLE-3-ACETIC ACID | — | 1997-10-16 | — | — | WO | claimed |
| WO-1997020034-A1 | AUXINIC ANALOGUES OF INDOLE-3-ACETIC ACID | LIFE TECHNOLOGIES, INC. (US) | 1997-06-05 | — | — | WO | claimed |
| US-11427569-B2 | Benzoimidazole indolyl methanes and methods of using them to inhibit PCKS9 and PCKS9-mediated ailments | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2022-08-30 | — | — | US | disclosed |
| US-20200262819-A1 | BENZOIMIDAZOLE INDOLYL METHANES AND METHODS OF USING THEM TO INHIBIT PCKS9 AND PCKS9-MEDIATED AILMENTS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2020-08-20 | — | — | US | disclosed |
| CN-103621505-A | Application of halogenated indole-3-acetic acid as herbicide | UNIV SOUTHEAST | 2014-03-12 | — | — | CN | disclosed |
| US-20080196124-A1 | Plant Growth Hormone Regulated Transcription Factors and Promoters Thereof | DONALD DANFORTH PLANT SCIENCE CENTER (US) | 2008-08-14 | — | — | US | disclosed |
| WO-2007127923-A2 | PLANT GROWTH HORMONE REGULATED TRANSCRIPTION FACTORS AND PROMOTERS THEREOF | DONALD DANFORTH PLANT SCIENCE CENTER (US) | 2007-11-08 | — | — | WO | disclosed |
| US-6361999-B1 | AMELIORATING DETRIMENTAL EFFECTS OF STRESS ON A PLANT OR PLANT TISSUE, SUCH AS ENVIRONMENTAL STRESS, PHYSICAL STRESS, CHEMICAL STRESS, FROM POLLUTION, CONTAMINATION, DROUGHT, AND LIGHT BY CONTACTING WITH AUXINIC INDOLE ACETIC ACID COMPOUND | LIFE TECHNOLOGIES, INC. | 2002-03-26 | — | — | US | disclosed |
| WO-2002002110-A1 | USE OF INDOLE-3-ACETIC ACID DERIVATIVES IN MEDICINE | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2002-01-10 | — | — | WO | disclosed |
| EP-0866850-A4 | AUXINIC ANALOGUES OF INDOLE-3-ACETIC ACID | LIFE TECHNOLOGIES INC (US) | 2000-11-22 | — | — | EP | disclosed |
| EP-0866850-A1 | AUXINIC ANALOGUES OF INDOLE-3-ACETIC ACID | LIFE TECHNOLOGIES, INC. (US) | 1998-09-30 | — | — | EP | disclosed |
| WO-1997020034-A9 | AUXINIC ANALOGUES OF INDOLE-3-ACETIC ACID | — | 1997-10-16 | — | — | WO | disclosed |
| WO-1997020034-A1 | AUXINIC ANALOGUES OF INDOLE-3-ACETIC ACID | LIFE TECHNOLOGIES, INC. (US) | 1997-06-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11427569-B2 | Benzoimidazole indolyl methanes and methods of using them to inhibit PCKS9 and PCKS9-mediated ailments | PCSK9, PCSK6, NEK9 | GPR84 1940/4885MPO 2501/4885SLC6A4 4451/4885 |
| US-20200262819-A1 | BENZOIMIDAZOLE INDOLYL METHANES AND METHODS OF USING THEM TO INHIBIT PCKS9 AND PCKS9-MEDIATED AILMENTS | PCSK9, PCSK6, NEK9 | GPR84 1940/4885MPO 2501/4885SLC6A4 4451/4885 |
| US-20030087762-A1 | Auxinic analogues of indole-3-acetic acid | AADAC, AADAT, AANAT | GPR84 2220/4885MPO 4401/4885SLC6A4 1193/4885 |
| US-20050107258-A1 | Auxinic analogues of indole-3-acetic acid | AADAC, AADAT, AANAT | GPR84 2200/4885MPO 4446/4885SLC6A4 1367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.