Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.48 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32684019 | 0.86 | HTR2A (0.60) | HTR2ASLC6A4NR4A2RIPK1AHR | |
| SCHEMBL8088111 | 0.86 | HTR2A (0.60) | HTR2ASLC6A4NR4A2RIPK1AHR | |
| SCHEMBL5694492 | 0.85 | TDP1 (0.53) | AKR1B1ALDH1A1TDP1TSHRLMNA | |
| SCHEMBL18509269 | 0.84 | HTR2A (0.63) | HTR2ASLC6A4NR4A2RIPK1PCSK9 | |
| SCHEMBL17102847 | 0.83 | ALDH1A1 (0.59) | AKR1B1ALDH1A1TDP1TSHRLMNA | |
| SCHEMBL25139668 | 0.83 | HTR2A (0.54) | HTR2ASLC6A4NR4A2RIPK1AHR | |
| SCHEMBL25139842 | 0.83 | HTR2A (0.54) | HTR2ASLC6A4NR4A2RIPK1AHR | |
| SCHEMBL5058671 | 0.82 | ALDH1A1 (0.46) | AKR1B1ALDH1A1TDP1TSHRLMNA | |
| SCHEMBL6284097 | 0.81 | HTR2A (0.58) | HTR2ANR4A2PCSK9ALDH1A1TDP1 | |
| SCHEMBL6512784 | 0.81 | CSNK2A2 (0.56) | HTR2AAKR1B1ALDH1A1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104311469-B | A kind of synthetic method of substituted indole-3-acetic acid | 东南大学 | 2016-10-26 | — | — | CN | disclosed |
| CN-104311469-A | Synthetic method of substituted indole-3-acetic acid | UNIV SOUTHEAST | 2015-01-28 | — | — | CN | disclosed |
| US-20050203166-A1 | Indole-3-acetic acid derivatives | CANCER RESEARCH TECHNOLOGY LIMITED | 2005-09-15 | — | — | US | disclosed |
| US-6890948-B1 | Use of indole-3-acetic acid derivatives in medicine | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2005-05-10 | — | — | US | disclosed |
| EP-1296676-B1 | USE OF INDOLE-3-ACETIC ACID DERIVATIVES IN MEDICINE | CANCER REC TECH LTD (GB) | 2004-01-28 | — | — | EP | disclosed |
| EP-1296676-A1 | USE OF INDOLE-3-ACETIC ACID DERIVATIVES IN MEDICINE | Cancer Research Technology Limited (GB) | 2003-04-02 | — | — | EP | disclosed |
| WO-2002002110-A1 | USE OF INDOLE-3-ACETIC ACID DERIVATIVES IN MEDICINE | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2002-01-10 | — | — | WO | disclosed |
| US-20010034887-A1 | Transformation of guar | JORSBOE MORTEN (DK) | 2001-10-25 | — | — | US | disclosed |
| US-6307127-B1 | TRANSFORMATION, REGENERATION AND SELECTION OF LEGUMES OF GENUS CYAMOPSIS, IN PARTICULAR AGROBACTERIUM-MEDIATED TRANSFORMATION OF GUAR(CYAMOPSIS TETRAGONOLOBA) TO GENETICALLY MODIFIED PLANTS BY USE OF BETA-LACTAMASE INHIBITOR SULBACTAM | DANISCO A/S (DK) | 2001-10-23 | — | — | US | disclosed |
| EP-0766743-A2 | TRANSFORMATION OF GUAR | DANISCO A/S (DK) | 1997-04-09 | — | — | EP | disclosed |
| WO-1995034667-A2 | TRANSFORMATION OF GUAR | DANISCO A/S (DK) | 1995-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050203166-A1 | Indole-3-acetic acid derivatives | ADCY3, GPR3, HCAR3 | HTR2A 1690/4885SLC6A4 458/4885NR4A2 1579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.