SCHEMBL5075249

SCHEMBL5075249

CCOCC(C)(C)CO[Si](C)(C)CCc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
ALDH1A1 P00352 4/20 0.36
HSD17B10 Q99714 1/20 0.36
TDP1 Q9NUW8 3/20 0.33
MAPT P10636 2/20 0.33
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
ALOX12 P18054 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
NPC1 O15118 3/20 0.33
CHRM2 P08172 1/20 0.33
HTR1A P08908 1/20 0.33
ADRA2A P08913 1/20 0.33
CHRM1 P11229 1/20 0.33
DRD1 P21728 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5085393 0.91 TDP1 (0.38) RAB9ASMN1; SMN2ALDH1A1HSD17B10TDP1
SCHEMBL5081556 0.89 RAB9A (0.33) RAB9ASMN1; SMN2ALDH1A1TDP1MAPT
SCHEMBL5075172 0.85 ALDH1A1 (0.38) SMN1; SMN2ALDH1A1SLC6A2TSHR
SCHEMBL5077166 0.85 LMNA (0.35) RAB9ASMN1; SMN2ALDH1A1TDP1MAPT
SCHEMBL5077356 0.83 ALDH1A1 (0.37) RAB9ASMN1; SMN2ALDH1A1HSD17B10MAPT
SCHEMBL8430157 0.81 POLB (0.39) RAB9AALDH1A1HSD17B10TDP1MAPT
SCHEMBL5078398 0.80 ALDH1A1 (0.33) RAB9ASMN1; SMN2ALDH1A1HSD17B10MAPT
SCHEMBL104845 0.79 TDP1 (0.41) RAB9ASMN1; SMN2ALDH1A1HSD17B10TDP1
SCHEMBL5081610 0.76 TSHR (0.31) MAPK1TSHR
SCHEMBL5081735 0.75 TAAR1 (0.36) RAB9ASMN1; SMN2ALDH1A1HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US claimed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US claimed
US-7399812-B2 Silicon ether compounds and a method for the preparation thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-07-15 US disclosed
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US disclosed
US-20060183873-A1 Silicon ether compounds and a method for the preparation thereof BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2006-08-17 US disclosed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US disclosed