Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13911248 | 0.88 | TDP1 (0.56) | MTORRAB9AGRM7CYP3A4TSHR | |
| SCHEMBL1118824 | 0.81 | MTOR (0.74) | MTORRAB9AGRM7CYP3A4TSHR | |
| SCHEMBL28729974 | 0.81 | MTOR (0.72) | MTORRAB9AGRM7CYP3A4TSHR | |
| SCHEMBL14139798 | 0.80 | SIGMAR1 (0.48) | MTORRAB9AGRM7CYP3A4TSHR | |
| SCHEMBL1485821 | 0.80 | SIGMAR1 (0.48) | MTORRAB9AGRM7CYP3A4TSHR | |
| SCHEMBL8095249 | 0.79 | MTOR (1.00) | MTORRAB9AGRM7CYP3A4TSHR | |
| SCHEMBL1469953 | 0.78 | CYP3A4 (0.61) | MTORRAB9AGRM7CYP3A4ALOX15 | |
| SCHEMBL8366747 | 0.78 | CYP3A4 (0.61) | MTORRAB9AGRM7CYP3A4ALOX15 | |
| SCHEMBL9019451 | 0.78 | CYP3A4 (0.61) | MTORRAB9AGRM7CYP3A4ALOX15 | |
| SCHEMBL11202137 | 0.78 | MTOR (0.42) | MTORRAB9AGRM7CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0671931-A4 | HEMOREGULATORY PEPTIDES. | SMITHKLINE BEECHAM CORP (US) | 1995-11-22 | — | — | EP | claimed |
| EP-0671931-A1 | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1995-09-20 | — | — | EP | claimed |
| US-20240208914-A1 | AMINOCYCLOBUTANES AS MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2024-06-27 | — | — | US | disclosed |
| CN-115335365-B | Aminocyclobutane as monoacylglycerol lipase modulators | 詹森药业有限公司 | 2024-06-18 | — | — | CN | disclosed |
| US-11919870-B2 | Aminocyclobutanes as monoacylglycerol lipase modulators | JANSSEN PHARMACEUTICA NV (BE) | 2024-03-05 | — | — | US | disclosed |
| US-20230331686-A1 | AMINOCYCLOBUTANES AS MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2023-10-19 | — | — | US | disclosed |
| US-11512059-B2 | Aminocyclobutanes as monoacylglycerol lipase modulators | JANSSEN PHARMACEUTICA NV (BE) | 2022-11-29 | — | — | US | disclosed |
| US-20210317094-A1 | AMINOCYCLOBUTANES AS MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2021-10-14 | — | — | US | disclosed |
| US-20210030785-A1 | METHOD OF PROPHYLAXIS OF ZIKA VIRUS INFECTION | STARPHARMA PTY LTD (AU) | 2021-02-04 | — | — | US | disclosed |
| CN-110937976-A | Organic compound, organic light-emitting element, display apparatus, image pickup apparatus, electronic apparatus, and moving object | 佳能株式会社 | 2020-03-31 | — | — | CN | disclosed |
| CN-110088148-A | The manufacturing method of 1,3,7- sarohornene polymer and its hydride and the polymer | 株式会社可乐丽 | 2019-08-02 | — | — | CN | disclosed |
| EP-0951532-A1 | BIVALENT AGONISTS FOR G-PROTEIN COUPLED RECEPTORS | YALE UNIVERSITY (US) | 1999-10-27 | — | — | EP | disclosed |
| WO-1998003632-A1 | BIVALENT AGONISTS FOR G-PROTEIN COUPLED RECEPTORS | YALE UNIVERSITY (US) | 1998-01-29 | — | — | WO | disclosed |
| US-4958029-A | Process for the production of isoindoline derivatives, novel intermediates and process for their production | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1990-09-18 | — | — | US | disclosed |
| EP-0275064-A2 | Process for the production of isoindoline derivatives, novel intermediates and process for their production | Banyu Pharmaceutical Co., Ltd. (JP) | 1988-07-20 | — | — | EP | disclosed |
| US-4576753-A | MICROBIOCIDES, ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-03-18 | — | — | US | disclosed |
| US-4472309-A | ANTIMICROBIAL | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | disclosed |
| US-4304718-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-12-08 | — | — | US | disclosed |
| US-4181800-A | ANTIBIOTICS FROM SUBSTITUTED PERHYDRO-S-TRIAZINES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-01-01 | — | — | US | disclosed |
| US-4147780-A | α-Amino-phosphonous acids for inhibiting bacteria and yeast | CIBA-GEIGY CORPORATION (US) | 1979-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11919870-B2 | Aminocyclobutanes as monoacylglycerol lipase modulators | MGLL, DAGLB, FAAH | MTOR 3220/4885RAB9A 1825/4885GRM7 966/4885 |
| US-11512059-B2 | Aminocyclobutanes as monoacylglycerol lipase modulators | MGLL, DAGLB, FAAH | MTOR 3220/4885RAB9A 1825/4885GRM7 966/4885 |
| US-20230331686-A1 | AMINOCYCLOBUTANES AS MONOACYLGLYCEROL LIPASE MODULATORS | MGLL, DAGLB, FAAH | MTOR 3220/4885RAB9A 1825/4885GRM7 966/4885 |
| US-20240208914-A1 | AMINOCYCLOBUTANES AS MONOACYLGLYCEROL LIPASE MODULATORS | MGLL, DAGLB, FAAH | MTOR 3220/4885RAB9A 1825/4885GRM7 966/4885 |
| US-20210030785-A1 | METHOD OF PROPHYLAXIS OF ZIKA VIRUS INFECTION | NAPA, CX3CR1, KISS1R | MTOR 4506/4885RAB9A 1532/4885GRM7 84/4885 |
| US-20210317094-A1 | AMINOCYCLOBUTANES AS MONOACYLGLYCEROL LIPASE MODULATORS | MGLL, DAGLB, FAAH | MTOR 3220/4885RAB9A 1825/4885GRM7 966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.