Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMOX1 | P09601 | 1/20 | 0.41 |
| ▸ | LPL | P06858 | 2/20 | 0.40 |
| ▸ | LIPC | P11150 | 2/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5079976 | 0.83 | GPR119 (0.50) | — | |
| SCHEMBL21409412 | 0.80 | CARM1 (0.54) | POLBHRH3CARM1PRMT6ALDH1A1 | |
| SCHEMBL4048177 | 0.78 | MGLL (0.36) | LPLLIPCLIPGMAPTHTT | |
| SCHEMBL4056560 | 0.77 | DGAT1 (0.47) | HMOX1 | |
| SCHEMBL17104609 | 0.77 | GPR119 (0.48) | HMOX1POLBCYP3A4MCHR1 | |
| SCHEMBL3983250 | 0.77 | GPR119 (0.41) | — | |
| SCHEMBL3988676 | 0.77 | CXCR4 (0.39) | POLBALDH1A1TSHR | |
| SCHEMBL28265428 | 0.77 | GRIN2D (0.39) | HMOX1LPLLIPCLIPGHRH3 | |
| SCHEMBL3981391 | 0.75 | NOS3 (0.38) | POLBALDH1A1KDM4EMCHR1TSHR | |
| SCHEMBL15224315 | 0.74 | CYP11B2 (0.45) | LPLLIPCLIPGCARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2059516-A1 | PYRIDINE COMPOUNDS FOR TREATING GPR119 RELATED DISORDERS | BIOVITRUM AB (publ) (SE) | 2009-05-20 | — | — | EP | disclosed |
| WO-2008025798-A1 | PYRIDINE COMPOUNDS FOR TREATING GPR119 RELATED DISORDERS | BIOVITRUM AB (PUBL) (SE) | 2008-03-06 | — | — | WO | disclosed |