SCHEMBL5080655

SCHEMBL5080655

CCOC(Oc1ccccc1)C(C)C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.43
LTA4H P09960 1/20 0.39
MTNR1A P48039 1/20 0.39
MTNR1B P49286 1/20 0.39
LMNA P02545 2/20 0.38
ALDH1A1 P00352 1/20 0.36
TSHR P16473 1/20 0.36
MAPK1 P28482 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
KDM4E B2RXH2 1/20 0.36
SLC6A4 P31645 1/20 0.36
GAA P10253 2/20 0.36
MAOA P21397 2/20 0.35
PTGS1 P23219 1/20 0.35
CA4 P22748 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
PKM P14618 1/20 0.34
CYP2C19 P33261 1/20 0.34
CHRNB4 P30926 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14830646 0.83 CA4 (0.43) LTA4HMTNR1AMTNR1BLMNAALDH1A1
SCHEMBL997422 0.79 LMNA (0.46) L3MBTL1LTA4HMTNR1AMTNR1BLMNA
SCHEMBL2607792 0.78 ALDH1A1 (0.45) L3MBTL1ALDH1A1TSHRTDP1GAA
SCHEMBL4865190 0.77 THRB (0.43) L3MBTL1LTA4HMTNR1AMTNR1BLMNA
SCHEMBL6693137 0.77 CHRNB2 (0.41) ALDH1A1CHRNB4CHRNA3
SCHEMBL5017310 0.76 TP53 (0.39) ALDH1A1TSHRMAPK1TDP1KDM4E
SCHEMBL6689016 0.75 KMT2A (0.35) ALDH1A1
SCHEMBL9658141 0.74 SLC1A3 (0.42) L3MBTL1LMNATSHRCYP1A2CYP2C9
SCHEMBL10788274 0.74 L3MBTL1 (0.42) L3MBTL1LTA4HMTNR1AMTNR1BLMNA
SCHEMBL16683081 0.74 SLC7A5 (0.54) ALDH1A1TSHRTDP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7358030-B2 Process for producing ether compound KYOWA YUKA CO., LTD. (JP) 2008-04-15 US disclosed
US-20060074262-A1 Process for producing ether compound KYOWA YUKA CO., LTD. (JP) 2006-04-06 US disclosed
US-7015363-B2 Process for producing ether compound KYOWA YUKA CO., LTD. (JP) 2006-03-21 US disclosed
US-20040181097-A1 Process for producing ether compound KYOWA YUKA CO., LTD. (JP) 2004-09-16 US disclosed
EP-1415968-A1 PROCESS FOR PRODUCING ETHER COMPOUND Kyowa Yuka Co., Ltd. (JP) 2004-05-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060074262-A1 Process for producing ether compound AGL, ARL1, CYP2C8 L3MBTL1 2043/4885LTA4H 369/4885MTNR1A 4071/4885
US-20040181097-A1 Process for producing ether compound CYP2E1, ARL1, MRPL21 L3MBTL1 2145/4885LTA4H 669/4885MTNR1A 3855/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.