SCHEMBL5080992

SCHEMBL5080992

CC1(C)CC(O)CC(C)(C)N1OCCc1ccccc1O

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 3/20 0.41
GAA P10253 1/20 0.37
TAAR1 Q96RJ0 1/20 0.37
MPO P05164 5/20 0.36
TYR P14679 1/20 0.36
KDM4E B2RXH2 1/20 0.35
HTR1A P08908 1/20 0.35
SLC6A4 P31645 1/20 0.35
EPHX2 P34913 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7527387 0.83 HRH3 (0.43) HRH3TAAR1MPOTYRKDM4E
SCHEMBL4985361 0.81 DHFR (0.41) GAAKDM4EEPHX2MEN1KMT2A
SCHEMBL6305131 0.79 KMT2A (0.43) HRH3GAATYREPHX2MEN1
SCHEMBL9039574 0.74 KMT2A (0.41) EPHX2KMT2A
SCHEMBL7114359 0.73 PTGFR (0.34) HRH3GAATYR
SCHEMBL9039403 0.71 CYP2D6 (0.31) GAA
SCHEMBL13008300 0.71 CYP2D6 (0.31) GAA
SCHEMBL9042599 0.71 KMT2A (0.33) GAAKMT2A
SCHEMBL9041491 0.70 CYP2D6 (0.31)
SCHEMBL9040335 0.70 CYP2D6 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030120077-A1 Hydroxy substituted N-alkoxy hindered amines and compositions stabilized therewith GALBO JAMES PETER (US) 2003-06-26 US claimed
US-6420562-B2 OXIDATION, HEAT AND RADIATION RESISTANCE CIBA SPECIALITY CHEMICALS CORPORATION 2002-07-16 US claimed
US-6420463-B1 HEAT RESISTANCE, OXIDATION RESISTANCE OR PHOTOSTABILITY CIBA SPECIALTY CHEMICALS CORP. 2002-07-16 US claimed
US-20020058735-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith GALBO JAMES PETER (US) 2002-05-16 US claimed
US-20020040145-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith GALBO JAMES P (US) 2002-04-04 US claimed
US-20010034449-A1 Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith GALBO JAMES P (US) 2001-10-25 US claimed
US-20010031872-A1 Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith GALBO JAMES P (US) 2001-10-18 US claimed
US-20010018520-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith GALBO JAMES P (US) 2001-08-30 US claimed
US-6391949-B1 None US disclosed
CN-1537876-B Multi-branch polymer, its production method and its application MITSU CHEMICALS INC 2013-01-16 CN disclosed
EP-1517926-B1 OXYGEN TAILORING OF POLYETHYLENE FILM RESINS EXXONMOBIL CHEM PATENTS INC (US) 2008-07-23 EP disclosed
US-7285617-B2 Oxygen tailoring of polyethylene blow molding resins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-23 US disclosed
US-7166659-B2 Substituted 5-aryl-2-(2-hydroxyphenyl)-2H-benzotriazole UV absorbers, compositions stabilized therewith and process for preparation thereof CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-01-23 US disclosed
US-7148274-B2 Substituted 5-aryl-2-(2-hydroxyphenyl)-2h-benzotriazole UV absorbers, compositions stabilized therewith and process for preparation thereof CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-12-12 US disclosed
US-20010034449-A1 Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith GALBO JAMES P (US) 2001-10-25 US disclosed
US-20010031872-A1 Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith GALBO JAMES P (US) 2001-10-18 US disclosed
US-20010020099-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith GALBO JAMES P (US) 2001-09-06 US disclosed
US-20010018520-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith GALBO JAMES P (US) 2001-08-30 US disclosed
US-20010016658-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith GALBO JAMES P (US) 2001-08-23 US disclosed
US-6271377-B1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith CIBA SPECIALTY CHEMICALS CORPORATION 2001-08-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020040145-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith POLH, OGG1, OGFOD1 HRH3 6/4885GAA 1582/4885TAAR1 794/4885
US-20020058735-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith OGG1, HAO2, POLH HRH3 10/4885GAA 1255/4885TAAR1 810/4885
US-20010016658-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith POLH, OGG1, OGFOD1 HRH3 6/4885GAA 1582/4885TAAR1 794/4885
US-20010034449-A1 Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith POLH, OGG1, OGFOD1 HRH3 6/4885GAA 1582/4885TAAR1 794/4885
US-20010020099-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith POLH, OGG1, OGFOD1 HRH3 6/4885GAA 1582/4885TAAR1 794/4885
US-20030120077-A1 Hydroxy substituted N-alkoxy hindered amines and compositions stabilized therewith OGG1, POLH, OGFOD1 HRH3 8/4885GAA 1590/4885TAAR1 804/4885
US-20010018520-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith POLH, OGG1, OGFOD1 HRH3 6/4885GAA 1582/4885TAAR1 794/4885
US-20010031872-A1 Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith POLH, OGG1, OGFOD1 HRH3 6/4885GAA 1582/4885TAAR1 794/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.