Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 5/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.32 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.32 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | IAPP | P10997 | 1/20 | 0.30 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9784227 | 0.83 | PTGFR (0.40) | PTGFRPTGER1ALDH1A1NR5A2PTGER2 | |
| SCHEMBL209037 | 0.82 | MAPT (0.37) | PTGFRPTGER1ALDH1A1PTGER2MAPT | |
| SCHEMBL7118388 | 0.81 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL994981 | 0.81 | PPARG (0.34) | PTGFRALDH1A1PTGER2MAPTAKR1B1 | |
| SCHEMBL6492997 | 0.80 | PTGFR (0.37) | PTGFRPTGER1NR5A2LTB4RPDK2 | |
| SCHEMBL4809149 | 0.80 | PTGER3 (0.33) | PTGFRPTGER1ALDH1A1NR5A2PTGER2 | |
| SCHEMBL993909 | 0.80 | PPARG (0.36) | PTGFRALDH1A1PTGER2MAPTAKR1B1 | |
| SCHEMBL7115492 | 0.80 | GPR84 (0.34) | ALDH1A1 | |
| SCHEMBL39175 | 0.79 | PPARG (0.39) | ALDH1A1MAPTAKR1B1 | |
| SCHEMBL995960 | 0.79 | PPARG (0.39) | ALDH1A1MAPTAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6638997-B2 | Used for stabilizing polyolefin and automotive coating formulation against the deleterious effects of oxidative, thermal and actinic radiation | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-10-28 | — | — | US | disclosed |
| US-6586507-B2 | For stabilizing polyolefins, especially thermoplastic polyolefins, against the deleterious effects of oxidative, thermal and actinic radiation, also for stabilizing acid catalyzed and ambient cured coatings systems | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-07-01 | — | — | US | disclosed |
| US-6420463-B1 | HEAT RESISTANCE, OXIDATION RESISTANCE OR PHOTOSTABILITY | CIBA SPECIALTY CHEMICALS CORP. | 2002-07-16 | — | — | US | disclosed |
| US-6388072-B2 | TETRAALKYL SUBSTITUTED PIPERIDINE SUBSTITUTED ON THE N-ATOM WITH O-E-OH GROUP (E= ALKYLENE OR PHENYLENE OR CYCLOALIPHATIC DERIVATIVES) ARE USED FOR STABILIZING POLYOLEFINS AND AUTOMOTIVE COATING AGAINST HEAT, OXIDATION | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-05-14 | — | — | US | disclosed |
| US-6380389-B2 | FOR POLYOLEFINS AND AUTOMOTIVE COATINGS; LIGHT, HEAT, OXIDATION RESISTANCE | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-04-30 | — | — | US | disclosed |
| US-6376584-B1 | OXIDATION RESISTANCE, HEAT RESISTANCE, PHOTOSTABILITY | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-04-23 | — | — | US | disclosed |
| US-20020040145-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | GALBO JAMES P (US) | 2002-04-04 | — | — | US | disclosed |
| US-20010020099-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | GALBO JAMES P (US) | 2001-09-06 | — | — | US | disclosed |
| US-20010016658-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | GALBO JAMES P (US) | 2001-08-23 | — | — | US | disclosed |
| US-6271377-B1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020040145-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | POLH, OGG1, OGFOD1 | PTGFR 4457/4885PTGER1 4574/4885ALDH1A1 1091/4885 |
| US-20010016658-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | POLH, OGG1, OGFOD1 | PTGFR 4457/4885PTGER1 4574/4885ALDH1A1 1091/4885 |
| US-20010020099-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | POLH, OGG1, OGFOD1 | PTGFR 4457/4885PTGER1 4574/4885ALDH1A1 1091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.