SCHEMBL5081469

SCHEMBL5081469

CCOCC(C)(C)CO[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DUT P33316 1/20 0.33
MAPK1 P28482 1/20 0.31
ALDH1A1 P00352 1/20 0.31
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5078703 0.89 DUT (0.38) DUTMAPK1ALDH1A1
SCHEMBL5078221 0.87 DUT (0.35) DUT
SCHEMBL5080794 0.85 MAPK1 (0.31) MAPK1ALDH1A1KDM4E
SCHEMBL5077762 0.82 NUDT1 (0.36) DUT
SCHEMBL5081544 0.78 SLC6A2 (0.33) DUTALDH1A1
SCHEMBL5081486 0.76 DUT (0.30) DUT
SCHEMBL5075172 0.76 ALDH1A1 (0.38) ALDH1A1
SCHEMBL238216 0.75 DUT (0.38) DUTALDH1A1KDM4E
SCHEMBL19356620 0.74 NCF1 (0.40) DUTALDH1A1KDM4E
SCHEMBL5075249 0.73 RAB9A (0.36) MAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US claimed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US claimed
US-7399812-B2 Silicon ether compounds and a method for the preparation thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-07-15 US disclosed
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US disclosed
US-20060183873-A1 Silicon ether compounds and a method for the preparation thereof BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2006-08-17 US disclosed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US disclosed