SCHEMBL5084057

SCHEMBL5084057

Oc1ccc2[c]cccc2c1O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN22 Q9Y2R2 1/20 0.45
IDO1 P14902 2/20 0.39
BAD Q92934 1/20 0.37
HPGD P15428 2/20 0.35
ALOX15 P16050 2/20 0.35
RECQL P46063 2/20 0.35
HSD17B10 Q99714 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
ALDH1A1 P00352 2/20 0.35
ADAMTS4 O75173 1/20 0.35
EGFR P00533 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
LMNA P02545 1/20 0.35
FYN P06241 1/20 0.35
MMP2 P08253 1/20 0.35
MMP9 P14780 1/20 0.35
MMP8 P22894 1/20 0.35
CA6 P23280 1/20 0.35
CDK2 P24941 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2411016 0.78 CYP1A2 (0.32)
SCHEMBL386939 0.76 HSD17B10 (0.44) IDO1HPGDALOX15RECQLHSD17B10
SCHEMBL2412656 0.74 HPRT1 (0.33)
SCHEMBL6630598 0.71 PTPN22 (0.41) PTPN22IDO1BADHPGDALOX15
SCHEMBL4599438 0.71 HPGD (0.41) PTPN22HPGDALOX15RECQLHSD17B10
SCHEMBL2407426 0.70 ALDH1A1 (0.35) PTPN22HPGDHSD17B10TDP1ALDH1A1
SCHEMBL9617105 0.69 PTPN22 (0.41) PTPN22HPGDHSD17B10ALDH1A1MAPT
SCHEMBL10433281 0.69 HTT (0.38) IDO1HPGDALOX15HSD17B10TDP1
SCHEMBL5081659 0.68 IDO1 (0.48) PTPN22IDO1HPGDALOX15RECQL
SCHEMBL50091 0.68 IDO1 (0.48) PTPN22IDO1HPGDALOX15RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3883916-A1 USE OF POLYHYDROXYAROMATIC COMPOUNDS FOR THE TREATMENT OF FIBROUS AMINO ACID BASED SUBSTRATES Momentive Performance Materials GmbH (DE) 2021-09-29 EP claimed
CN-113329993-A Use of polyhydroxy aromatic compounds for treating fibrous substrates based on amino acids 迈图高新材料有限责任公司 2021-08-31 CN claimed
US-20200163850-A1 USE OF POLYHYDROXYAROMATIC COMPOUNDS FOR THE TREATMENT OF FIBROUS AMINO ACID BASED SUBSTRATES CITIBANK, N.A., AS ADMINISTRATIVE AGENT 2020-05-28 US claimed
US-20080027023-A1 Antiproliferative Compositions Comprising Aryl Substituted Xylopyranoside Derivatives GLUCOGENE MEDICAL HFM AB (SE) 2008-01-31 US claimed
EP-1765363-A2 NEW COMPOSITIONS GLUCOGENE MEDICAL HFM AB (SE) 2007-03-28 EP claimed
WO-2006006933-A2 ANTIPROLIFERATIVE COMPOSITIONS COMPRISING ARYL SUBSTITUTED XYLOPYRANOSIDE DERIVATIVES GLUCOGENE MEDICAL HFM AB (SE) 2006-01-19 WO claimed
US-20030092637-A1 Novel compounds XYLOGEN AB (SE) 2003-05-15 US claimed
EP-3883916-A1 USE OF POLYHYDROXYAROMATIC COMPOUNDS FOR THE TREATMENT OF FIBROUS AMINO ACID BASED SUBSTRATES Momentive Performance Materials GmbH (DE) 2021-09-29 EP disclosed
CN-113329993-A Use of polyhydroxy aromatic compounds for treating fibrous substrates based on amino acids 迈图高新材料有限责任公司 2021-08-31 CN disclosed
US-20200163850-A1 USE OF POLYHYDROXYAROMATIC COMPOUNDS FOR THE TREATMENT OF FIBROUS AMINO ACID BASED SUBSTRATES CITIBANK, N.A., AS ADMINISTRATIVE AGENT 2020-05-28 US disclosed
CN-1276035-C Water-color ink MITSUI CHEMICALS INC (JP) 2006-09-20 CN disclosed
CN-1558934-A Water-color ink 三井化学株式会社 2004-12-29 CN disclosed
US-20040231558-A1 Has a clear hue, high light fastness and high moisture resistance MITSUI CHEMICALS, INC. (JP) 2004-11-25 US disclosed
US-5629406-A AMINO ACID DERIVATIVES SANKYO COMPANY, LIMITED (JP) 1997-05-13 US disclosed
CN-1091432-A Can suppress the active peptide of hiv protease, its preparation with and medical use SANKYO CO (JP) 1994-08-31 CN disclosed
CN-1091128-A Piperidine derivative SANKYO CO (JP) 1994-08-24 CN disclosed
EP-0587311-A1 Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use SANKYO COMPANY LIMITED (JP) 1994-03-16 EP disclosed
EP-0583971-A1 Piperidine derivatives SANKYO COMPANY LIMITED (JP) 1994-02-23 EP disclosed
CN-1064683-A New beta-amino-alpha-hydroxycarboxylic acids and uses thereof SANKYO CO (JP) 1992-09-23 CN disclosed
EP-0498680-A1 New beta-amino-alpha-hydroxycarboxylic acids and their use Sankyo Company Limited (JP) 1992-08-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030092637-A1 Novel compounds ENTPD5, G6PD, G6PC1 PTPN22 847/4885IDO1 1329/4885BAD 785/4885
US-20080027023-A1 Antiproliferative Compositions Comprising Aryl Substituted Xylopyranoside Derivatives UGGT1, B3GAT3, MKI67 PTPN22 10/4885IDO1 496/4885BAD 1135/4885
US-20200163850-A1 USE OF POLYHYDROXYAROMATIC COMPOUNDS FOR THE TREATMENT OF FIBROUS AMINO ACID BASED SUBSTRATES PAH, CUTA, ASPH PTPN22 2893/4885IDO1 97/4885BAD 3644/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.