Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL188482 | 1.00 | ALDH1A1 (0.42) | ALDH1A1TSHRL3MBTL1SOAT1CYP2C9 | |
| SCHEMBL4642638 | 1.00 | ALDH1A1 (0.42) | ALDH1A1TSHRL3MBTL1SOAT1CYP2C9 | |
| SCHEMBL600809 | 0.85 | ALDH1A1 (0.40) | ALDH1A1TSHRL3MBTL1SOAT1CYP2C9 | |
| SCHEMBL600808 | 0.85 | ALDH1A1 (0.40) | ALDH1A1TSHRL3MBTL1SOAT1CYP2C9 | |
| SCHEMBL4517991 | 0.84 | ALDH1A1 (0.52) | ALDH1A1TSHRL3MBTL1SOAT1CYP2C9 | |
| SCHEMBL4517988 | 0.84 | ALDH1A1 (0.52) | ALDH1A1TSHRL3MBTL1SOAT1CYP2C9 | |
| SCHEMBL16269710 | 0.84 | ALDH1A1 (0.52) | ALDH1A1TSHRL3MBTL1SOAT1CYP2C9 | |
| SCHEMBL6211263 | 0.82 | ALOX15 (0.41) | ALDH1A1TSHRL3MBTL1SOAT1CYP2C9 | |
| SCHEMBL6211261 | 0.82 | ALOX15 (0.41) | ALDH1A1TSHRL3MBTL1SOAT1CYP2C9 | |
| SCHEMBL16269712 | 0.82 | ALDH1A1 (0.38) | ALDH1A1TSHRL3MBTL1CYP2C9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117843616-B | 3-Cyano-substituted quinoline compound, and pharmaceutical composition and application thereof | 中国药科大学 | 2025-05-27 | — | — | CN | disclosed |
| CN-117843616-A | 3-cyano-substituted quinoline compound, and pharmaceutical composition and application thereof | 中国药科大学 | 2024-04-09 | — | — | CN | disclosed |
| CN-108473497-B | EP4 antagonists | 卫材R&D 管理有限公司 | 2021-09-10 | — | — | CN | disclosed |
| CN-110914263-A | Substituted bicyclic heterocyclic compounds as NADPH oxidase inhibitors | 格兰马克药品股份有限公司 | 2020-03-24 | — | — | CN | disclosed |
| EP-3215505-B1 | PIPERIDINYLPYRAZOLOPYRIMIDINONES AND THEIR USE | Bayer Pharma AG (DE) | 2019-07-24 | — | — | EP | disclosed |
| US-10118930-B2 | Piperidinylpyrazolopyrimidinones and their use | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-11-06 | — | — | US | disclosed |
| US-9920059-B2 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-03-20 | — | — | US | disclosed |
| US-20170334917-A1 | PIPERIDINYLPYRAZOLOPYRIMIDINONES AND THEIR USE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-11-23 | — | — | US | disclosed |
| EP-3215505-A1 | PIPERIDINYLPYRAZOLOPYRIMIDINONES AND THEIR USE | Bayer Pharma Aktiengesellschaft (DE) | 2017-09-13 | — | — | EP | disclosed |
| US-20170226107-A1 | Heterocyclic Compounds as Pesticides | BRETSCHNEIDER, NIKLAS TIM (DE) | 2017-08-10 | — | — | US | disclosed |
| US-9688681-B2 | Heterocyclic compounds as pest control agents | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-06-27 | — | — | US | disclosed |
| WO-2016071216-A1 | PIPERIDINYLPYRAZOLOPYRIMIDINONES AND THEIR USE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-05-12 | — | — | WO | disclosed |
| US-20160122353-A1 | HETEROCYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-05-05 | — | — | US | disclosed |
| US-20120028973-A1 | NITROIMIDAZOOXAZINES AND THEIR USES IN ANTI-TUBERCULAR THERAPY | GLOBAL ALLIANCE FOR TB DRUG DEVELOPMENT (US) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170226107-A1 | Heterocyclic Compounds as Pesticides | DDT, ACHE, GLRX3 | ALDH1A1 1260/4885TSHR 451/4885L3MBTL1 535/4885 |
| US-20160122353-A1 | HETEROCYCLIC COMPOUNDS AS PEST CONTROL AGENTS | DDT, NISCH, ACHE | ALDH1A1 2915/4885TSHR 3554/4885L3MBTL1 129/4885 |
| US-10118930-B2 | Piperidinylpyrazolopyrimidinones and their use | HAMP, SERPINC1, PRSS8 | ALDH1A1 404/4885TSHR 3606/4885L3MBTL1 4443/4885 |
| US-20170334917-A1 | PIPERIDINYLPYRAZOLOPYRIMIDINONES AND THEIR USE | HAMP, SERPINC1, PRSS8 | ALDH1A1 404/4885TSHR 3606/4885L3MBTL1 4443/4885 |
| US-20120028973-A1 | NITROIMIDAZOOXAZINES AND THEIR USES IN ANTI-TUBERCULAR THERAPY | NOX5, MT-ND5, NQO1 | ALDH1A1 1870/4885TSHR 1851/4885L3MBTL1 3585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.