Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 3/20 | 0.39 |
| ▸ | CASP7 | P55210 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2934286 | 0.96 | HTR7 (0.40) | HTR7TMEM97SIGMAR1RAB9ANPC1 | |
| SCHEMBL2833638 | 0.88 | CNR2 (0.46) | HTR7TMEM97SIGMAR1RAB9ANPC1 | |
| SCHEMBL2833643 | 0.88 | CNR2 (0.46) | HTR7TMEM97SIGMAR1RAB9ANPC1 | |
| SCHEMBL640463 | 0.87 | RAB9A (0.41) | HTR7TMEM97SIGMAR1RAB9ANPC1 | |
| SCHEMBL639832 | 0.85 | CNR2 (0.43) | HTR7TMEM97SIGMAR1RAB9ANPC1 | |
| SCHEMBL3313366 | 0.85 | CNR2 (0.43) | HTR7TMEM97SIGMAR1RAB9ANPC1 | |
| SCHEMBL13649888 | 0.84 | PSEN1 (0.53) | HTR7TMEM97SIGMAR1RAB9ANPC1 | |
| SCHEMBL10246104 | 0.83 | NPC1 (0.43) | HTR7TMEM97SIGMAR1RAB9ANPC1 | |
| SCHEMBL640467 | 0.83 | CASP3 (0.40) | HTR7TMEM97SIGMAR1RAB9ANPC1 | |
| SCHEMBL2307993 | 0.83 | HTR7 (0.43) | HTR7TMEM97SIGMAR1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080306084-A1 | Substituted Amide Compounds | GRUENENTHAL GMBH (DE) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306084-A1 | Substituted Amide Compounds | OPRK1, NAA50, ACMSD | HTR7 1873/4885TMEM97 2636/4885SIGMAR1 84/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.