Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GLB1 | P16278 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CTRC | Q99895 | 1/20 | 0.41 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL204164 | 0.87 | ALDH1A1 (0.48) | THRBRECQLTDP1ALDH1A1CYP3A4 | |
| SCHEMBL202598 | 0.87 | ALDH1A1 (0.48) | THRBRECQLTDP1ALDH1A1CYP3A4 | |
| SCHEMBL7589676 | 0.85 | SMAD3 (0.37) | THRBRECQLTDP1ALDH1A1CYP3A4 | |
| SCHEMBL6415903 | 0.81 | SMAD3 (0.35) | THRBRECQLTDP1ALDH1A1CYP3A4 | |
| SCHEMBL8359568 | 0.78 | TDP1 (0.43) | THRBRECQLTDP1ALDH1A1CYP3A4 | |
| SCHEMBL229962 | 0.78 | ALDH1A1 (0.43) | THRBRECQLTDP1ALDH1A1CYP3A4 | |
| SCHEMBL29389278 | 0.77 | THRB (0.41) | THRBRECQLTDP1ALDH1A1CYP3A4 | |
| SCHEMBL4593779 | 0.77 | THRB (0.41) | THRBRECQLTDP1ALDH1A1CYP3A4 | |
| SCHEMBL18171688 | 0.76 | ALDH1A1 (0.44) | THRBRECQLTDP1ALDH1A1CYP3A4 | |
| SCHEMBL3472516 | 0.74 | THRB (0.44) | THRBRECQLTDP1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7460223-B2 | Inverted orientation for a microplate | APPLIED BIOSYSTEMS INC. (US) | 2008-12-02 | — | — | US | disclosed |