Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMAD3 | P84022 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 3/20 | 0.34 |
| ▸ | RECQL | P46063 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GLB1 | P16278 | 1/20 | 0.34 |
| ▸ | CTRC | Q99895 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
| ▸ | TYMS | P04818 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7589676 | 0.88 | SMAD3 (0.37) | SMAD3THRBRECQLTDP1MEN1 | |
| SCHEMBL6415591 | 0.85 | MEN1 (0.34) | SMAD3THRBRECQLTDP1MEN1 | |
| SCHEMBL202968 | 0.81 | GNG2 (0.43) | SMAD3THRBRECQLTDP1MEN1 | |
| SCHEMBL5094500 | 0.81 | THRB (0.41) | SMAD3THRBRECQLTDP1MEN1 | |
| SCHEMBL203192 | 0.80 | GNG2 (0.43) | SMAD3THRBRECQLTDP1MEN1 | |
| SCHEMBL202598 | 0.78 | ALDH1A1 (0.48) | SMAD3THRBRECQLTDP1MEN1 | |
| SCHEMBL3358989 | 0.74 | MEN1 (0.33) | THRBRECQLTDP1MEN1BLM | |
| SCHEMBL1738599 | 0.74 | MEN1 (0.33) | THRBRECQLTDP1MEN1BLM | |
| SCHEMBL202849 | 0.74 | RECQL (0.42) | SMAD3THRBRECQLTDP1MEN1 | |
| SCHEMBL18171688 | 0.73 | ALDH1A1 (0.44) | SMAD3THRBRECQLTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050220675-A1 | High density plate filler | APPLIED BIOSYSTEMS, LLC | 2005-10-06 | — | — | US | disclosed |