Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.67 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27878587 | 0.98 | NQO1 (0.64) | NQO1CYP2A6TSHRTDP1MAOB | |
| SCHEMBL921673 | 0.94 | LTA4H (0.61) | NQO1CYP2A6TSHRTDP1MAOB | |
| SCHEMBL10485751 | 0.94 | NQO1 (0.58) | NQO1CYP2A6TSHRTDP1MAOB | |
| Alcohol SCHEMBL29171755 | 0.94 | NQO1 (0.58) | NQO1CYP2A6TSHRTDP1MAOB | |
| SCHEMBL12726667 | 0.94 | NQO1 (0.58) | NQO1CYP2A6TSHRMAOBMAPT | |
| SCHEMBL8041598 | 0.94 | NQO1 (0.58) | NQO1CYP2A6TSHRMAOBMAPT | |
| SCHEMBL27931308 | 0.90 | CYP2A6 (0.55) | NQO1CYP2A6TSHRTDP1MAOB | |
| Ammonia Solution, Strong SCHEMBL3938785 | 0.90 | NQO1 (0.54) | NQO1CYP2A6TSHRTDP1MAOB | |
| SCHEMBL11677967 | 0.88 | GAA (0.56) | NQO1TDP1MAPTALDH1A1GAA | |
| SCHEMBL10485807 | 0.88 | RELA (0.65) | NQO1MAPTALDH1A1TP53RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 245 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332733-B | Dapagliflozin middle Synthesis process of intermediate | 江苏阿尔法药业股份有限公司 | 2025-02-11 | — | — | CN | claimed |
| CN-117720401-A | Synthesis method of dapagliflozin intermediate | 江苏阿尔法药业股份有限公司 | 2024-03-19 | — | — | CN | claimed |
| CN-116332733-A | Synthesis process of dapagliflozin intermediate | 江苏阿尔法药业股份有限公司 | 2023-06-27 | — | — | CN | claimed |
| CN-115160321-A | Vardenafil analogue and synthetic method and application thereof | 广东西捷药业有限公司 | 2022-10-11 | — | — | CN | claimed |
| CN-113583003-A | Vardenafil analogue and synthetic method and application thereof | 广东西捷药业有限公司 | 2021-11-02 | — | — | CN | claimed |
| CN-107311847-B | Preparation method of 5-bromo-2-chloro-4' -ethoxy diphenylmethane | 安徽省诚联医药科技有限公司 | 2020-11-10 | — | — | CN | claimed |
| EP-3362450-B1 | N1- AND N7-SUBSTITUTED SIBIRILINE DERIVATIVES AND THEIR USE AS INHIBITORS OF CELLULAR NECROPTOSIS | INST NAT SANTE RECH MED (FR) | 2020-07-01 | — | — | EP | claimed |
| US-20180312502-A1 | N1-And N7-Substituted Sibiriline Derivatives And Their Use As Inhibitor Of Cellular Necroptosis | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2018-11-01 | — | — | US | claimed |
| EP-3362450-A1 | N1- AND N7-SUBSTITUTED SIBIRILINE DERIVATIVES AND THEIR USE AS INHIBITOR OF CELLULAR NECROPTOSIS | Institut National de la Sante et de la Recherche Medicale (INSERM) (FR) | 2018-08-22 | — | — | EP | claimed |
| CN-107311847-A | The preparation method of the chlorine 4` ethoxy diphenyl methane of 5 bromine 2 | 安徽省诚联医药科技有限公司 | 2017-11-03 | — | — | CN | claimed |
| WO-2017064216-A1 | N1- AND N7-SUBSTITUTED SIBIRILINE DERIVATIVES AND THEIR USE AS INHIBITOR OF CELLULAR NECROPTOSIS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2017-04-20 | — | — | WO | claimed |
| EP-2477509-B1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2014-07-30 | — | — | EP | claimed |
| US-7572824-B2 | Methods for minimizing thioamide impurities | WYETH (US) | 2009-08-11 | — | — | US | claimed |
| EP-1732922-B1 | METHODS FOR MINIMIZING THIOAMIDE IMPURITIES | WYETH CORP (US) | 2008-10-01 | — | — | EP | claimed |
| US-20080071083-A1 | Methods for minimizing thioamide impurities | WYETH (US) | 2008-03-20 | — | — | US | claimed |
| US-7314932-B2 | Methods for minimizing thioamide impurities | WYETH (US) | 2008-01-01 | — | — | US | claimed |
| EP-1732922-A1 | METHODS FOR MINIMIZING THIOAMIDE IMPURITIES | Wyeth (US) | 2006-12-20 | — | — | EP | claimed |
| WO-2005100347-A1 | METHODS FOR MINIMIZING THIOAMIDE IMPURITIES | WYETH (US) | 2005-10-27 | — | — | WO | claimed |
| US-20050228179-A1 | Methods for minimizing thioamide impurities | WYETH (US) | 2005-10-13 | — | — | US | claimed |
| CN-1539821-A | Molecule material of teera aryl aether pentacites | 复旦大学 | 2004-10-27 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050228179-A1 | Methods for minimizing thioamide impurities | TST, TXN, TTR | NQO1 201/4885CYP2A6 915/4885TSHR 339/4885 |
| US-20080071083-A1 | Methods for minimizing thioamide impurities | TST, TPMT, TXN | NQO1 430/4885CYP2A6 1274/4885TSHR 329/4885 |
| US-20180312502-A1 | N1-And N7-Substituted Sibiriline Derivatives And Their Use As Inhibitor Of Cellular Necroptosis | CASP7, RIPK3, PARK7 | NQO1 1497/4885CYP2A6 4619/4885TSHR 4144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.