Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
| ▸ | HTR3B | O95264 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.34 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6653085 | 0.98 | KMT2A (0.39) | MEN1KMT2ARAB9ANPC1L3MBTL1 | |
| SCHEMBL6651700 | 0.96 | MEN1 (0.38) | MEN1KMT2ARAB9ANPC1L3MBTL1 | |
| SCHEMBL6650438 | 0.89 | MEN1 (0.41) | MEN1KMT2ARAB9ANPC1L3MBTL1 | |
| SCHEMBL10102246 | 0.88 | MEN1 (0.40) | MEN1KMT2ARAB9ANPC1L3MBTL1 | |
| SCHEMBL4798246 | 0.86 | PLA2G2A (0.41) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL7784131 | 0.81 | MAPT (0.39) | MEN1KMT2ARAB9ANPC1L3MBTL1 | |
| SCHEMBL6653732 | 0.81 | MEN1 (0.40) | MEN1KMT2ARAB9ANPC1L3MBTL1 | |
| SCHEMBL7785467 | 0.80 | KDM4E (0.39) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL6650817 | 0.78 | KMT2A (0.41) | MEN1KMT2ARAB9ANPC1L3MBTL1 | |
| SCHEMBL13005296 | 0.78 | MAPT (0.42) | MEN1KMT2AL3MBTL1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040191520-A1 | Photochromic articles with reduced temperature dependency and methods for preparation | TRANSITIONS OPTICAL LIMITED (IE) | 2004-09-30 | — | — | US | claimed |
| EP-1248778-B1 | SUBSTITUTED PHOTOCHROMIC 2H-NAPHTHO 1,2-B] PYRAN COMPOUNDS | PPG IND OHIO INC (US) | 2004-06-16 | — | — | EP | claimed |
| US-6340766-B1 | PHOTOCHROMIC DYES ON SUBSTRATES LIKE GLASS WITH PROTECTIVE COATINGS | TRANSITION OPTICAL, INC. | 2002-01-22 | — | — | US | claimed |
| US-20020007078-A1 | Novel substituted naphthopyrans | TRANSITIONS OPTICAL LIMITED (IE) | 2002-01-17 | — | — | US | claimed |
| US-7320826-B2 | comprises 3-(4-methoxyphenyl)-3-phenyl-6,7,10,11-tetramethoxy-13-ethyl-13-hydroxy-13H-3H-indeno[2,'3,'3,4]naphtho[1,2-b]pyran; for activation via actinic radiation; improved optical density response; ophthalmic lens | PPG INDUSTRIES OHIO, INC. (US) | 2008-01-22 | — | — | US | disclosed |
| US-20040191520-A1 | Photochromic articles with reduced temperature dependency and methods for preparation | TRANSITIONS OPTICAL LIMITED (IE) | 2004-09-30 | — | — | US | disclosed |
| EP-1248778-B1 | SUBSTITUTED PHOTOCHROMIC 2H-NAPHTHO 1,2-B] PYRAN COMPOUNDS | PPG IND OHIO INC (US) | 2004-06-16 | — | — | EP | disclosed |
| US-6340766-B1 | PHOTOCHROMIC DYES ON SUBSTRATES LIKE GLASS WITH PROTECTIVE COATINGS | TRANSITION OPTICAL, INC. | 2002-01-22 | — | — | US | disclosed |
| US-20020007078-A1 | Novel substituted naphthopyrans | TRANSITIONS OPTICAL LIMITED (IE) | 2002-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020007078-A1 | Novel substituted naphthopyrans | CRYZ, NR2E3, UACA | MEN1 4666/4885KMT2A 2921/4885RAB9A 4499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.