Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.32 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6653085 | 0.96 | KMT2A (0.39) | MEN1KMT2ARAB9ANPC1L3MBTL1 | |
| SCHEMBL5097833 | 0.96 | MEN1 (0.40) | MEN1KMT2ARAB9ANPC1L3MBTL1 | |
| SCHEMBL10102246 | 0.93 | MEN1 (0.40) | MEN1KMT2ARAB9ANPC1L3MBTL1 | |
| SCHEMBL6650438 | 0.91 | MEN1 (0.41) | MEN1KMT2ARAB9ANPC1L3MBTL1 | |
| SCHEMBL6653732 | 0.84 | MEN1 (0.40) | MEN1KMT2ARAB9ANPC1L3MBTL1 | |
| SCHEMBL4798246 | 0.82 | PLA2G2A (0.41) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL7784131 | 0.80 | MAPT (0.39) | MEN1KMT2ARAB9ANPC1L3MBTL1 | |
| SCHEMBL7785467 | 0.79 | KDM4E (0.39) | MEN1KMT2AL3MBTL1MAPTUSP2 | |
| SCHEMBL6650817 | 0.78 | KMT2A (0.41) | MEN1KMT2ARAB9ANPC1L3MBTL1 | |
| SCHEMBL5107478 | 0.78 | NR4A2 (0.37) | MEN1KMT2ATDP1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1248778-B1 | SUBSTITUTED PHOTOCHROMIC 2H-NAPHTHO 1,2-B] PYRAN COMPOUNDS | PPG IND OHIO INC (US) | 2004-06-16 | — | — | EP | claimed |
| US-6340766-B1 | PHOTOCHROMIC DYES ON SUBSTRATES LIKE GLASS WITH PROTECTIVE COATINGS | TRANSITION OPTICAL, INC. | 2002-01-22 | — | — | US | claimed |
| US-20020007078-A1 | Novel substituted naphthopyrans | TRANSITIONS OPTICAL LIMITED (IE) | 2002-01-17 | — | — | US | claimed |
| EP-1248778-B1 | SUBSTITUTED PHOTOCHROMIC 2H-NAPHTHO 1,2-B] PYRAN COMPOUNDS | PPG IND OHIO INC (US) | 2004-06-16 | — | — | EP | disclosed |
| US-6340766-B1 | PHOTOCHROMIC DYES ON SUBSTRATES LIKE GLASS WITH PROTECTIVE COATINGS | TRANSITION OPTICAL, INC. | 2002-01-22 | — | — | US | disclosed |
| US-20020007078-A1 | Novel substituted naphthopyrans | TRANSITIONS OPTICAL LIMITED (IE) | 2002-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020007078-A1 | Novel substituted naphthopyrans | CRYZ, NR2E3, UACA | MEN1 4666/4885KMT2A 2921/4885RAB9A 4499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.