SCHEMBL511745

SCHEMBL511745

C=COBOc1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.36
LTA4H P09960 1/20 0.36
ALDH1A1 P00352 1/20 0.33
CA4 P22748 1/20 0.33
SRC P12931 1/20 0.32
THRB P10828 1/20 0.32
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
KCNA3 P22001 1/20 0.31
TGM2 P21980 1/20 0.31
ALOX15 P16050 1/20 0.30
CA5A P35218 1/20 0.30
CA5B Q9Y2D0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28822737 0.78 NFE2L2 (0.35)
SCHEMBL28956767 0.78 ACHE (0.39) TSHRALDH1A1TDP1
SCHEMBL711694 0.77 LMNA (0.36) TSHRLTA4HALDH1A1CA4SRC
SCHEMBL8885 0.77 LTA4H (0.50) TSHRLTA4HALDH1A1CA4SRC
SCHEMBL28642433 0.77 CYP1A2 (0.37) ALDH1A1
SCHEMBL4611694 0.77 ACHE (0.47) ALDH1A1TDP1L3MBTL1
Hydrochloric Acid SCHEMBL693111 0.75 LTA4H (0.47) TSHRLTA4HALDH1A1CA4SRC
SCHEMBL6113933 0.74 CA4 (0.36) TSHRLTA4HCA4
SCHEMBL4787763 0.72 CYP3A4 (0.36) TSHRLTA4HALDH1A1THRBKCNA3
SCHEMBL29544396 0.72 LTA4H (0.45) TSHRLTA4HALDH1A1CA4SRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113797383-A High-elasticity high-drug-loading-rate embolism microsphere and preparation method thereof 迪格瑞医疗科技(苏州)有限公司 2021-12-17 CN claimed
WO-2000010007-A9 DEVICES AND METHODS FOR ANALYSIS OF NON-IONIC SOLUTES CALIFORNIA INST OF TECHN (US) 2000-07-06 WO claimed
WO-2000010007-A2 DEVICES AND METHODS FOR ANALYSIS OF NON-IONIC SOLUTES CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2000-02-24 WO claimed
WO-2025093746-A1 ADHESION-PROMOTING COMPOUNDS AND USE THEREOF UNIVERSITY OF NORTHUMBRIA AT NEWCASTLE (GB) 2025-05-08 WO disclosed
WO-2024256192-A1 PURIFICATION OF ENVELOPED OR MEMBRANOUS BIOLOGICAL PARTICLES CYTIVA BIOPROCESS R&D AB (SE) 2024-12-19 WO disclosed
US-20240295070-A1 ARTICLES WITH HYDROPHOBIC COATINGS OF BORONIC ACID-CONTAINING SILOXANE POLYMERS AND METHODS OF MAKING THEM UNIVERSITY OF ROCHESTER (US) 2024-09-05 US disclosed
CN-116802152-A Purification of bauxite ore using boric acid functionalized compounds 埃科莱布美国股份有限公司 2023-09-22 CN disclosed
US-11602724-B2 Visible light induced photogeneration of ground state atomic oxygen SAINT LOUIS UNIVERSITY (US) 2023-03-14 US disclosed
WO-2022272177-A1 ARTICLES WITH HYDROPHOBIC COATINGS OF BORONIC ACID-CONTAINING SILOXANE POLYMERS AND METHODS OF MAKING THEM UNIVERSITY OF ROCHESTER (US) 2022-12-29 WO disclosed
CN-110922546-B Phenyl hydroxyl compound ATRP method modified polycarboxylic acid slump retaining agent and preparation method thereof 湖北工业大学 2022-07-05 CN disclosed
CN-113387777-B Meta-alkenyl or aryl substituted phenol compound and preparation method and application thereof 广州大学 2022-03-29 CN disclosed
WO-2010025872-A2 ALFA-CARBOLINE INHIBITORS OF NPM-ALK, RET, AND BCR-ABL UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA (IT) 2010-03-11 WO disclosed
EP-2161271-A1 Alpha-carboline inhibitors of NMP-ALK, RET, and Bcr-Abl Università Degli Studi Di Milano - Bicocca (IT) 2010-03-10 EP disclosed
US-6906135-B2 Graft copolymers JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2005-06-14 US disclosed
EP-1337567-B1 GRAFT COPOLYMERS JOHNSON MATTHEY PLC (GB) 2004-09-15 EP disclosed
US-20040034117-A1 Graft copolymers JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2004-02-19 US disclosed
EP-1337567-A1 GRAFT COPOLYMERS JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2003-08-27 EP disclosed
WO-2002036648-A1 GRAFT COPOLYMERS JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2002-05-10 WO disclosed
WO-2000010007-A9 DEVICES AND METHODS FOR ANALYSIS OF NON-IONIC SOLUTES CALIFORNIA INST OF TECHN (US) 2000-07-06 WO disclosed
WO-2000010007-A2 DEVICES AND METHODS FOR ANALYSIS OF NON-IONIC SOLUTES CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2000-02-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11602724-B2 Visible light induced photogeneration of ground state atomic oxygen PPOX, SOD1, NFE2L2 TSHR 3430/4885LTA4H 1991/4885ALDH1A1 843/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.