SCHEMBL711694

SCHEMBL711694

O=COBOc1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.36
GAA P10253 1/20 0.36
KMT2A Q03164 1/20 0.36
TSHR P16473 2/20 0.36
LTA4H P09960 1/20 0.36
ALDH1A1 P00352 2/20 0.33
CA4 P22748 1/20 0.33
CYP2A6 P11509 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
SRC P12931 1/20 0.32
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ALOX15 P16050 1/20 0.31
KCNA3 P22001 1/20 0.31
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
PPARG P37231 1/20 0.31
NFE2L2 Q16236 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL511745 0.77 TSHR (0.36) TSHRLTA4HALDH1A1CA4SRC
SCHEMBL8885 0.77 LTA4H (0.50) TSHRLTA4HALDH1A1CA4CA1
Hydrochloric Acid SCHEMBL693111 0.75 LTA4H (0.47) KMT2ATSHRLTA4HALDH1A1CA4
SCHEMBL6113933 0.74 CA4 (0.36) TSHRLTA4HCA4
SCHEMBL9747855 0.72 TSHR (0.38) LMNAGAAKMT2ATSHRLTA4H
SCHEMBL1797563 0.72 LMNA (0.33) LMNAGAAKMT2ATSHRLTA4H
SCHEMBL29544396 0.72 LTA4H (0.45) TSHRLTA4HALDH1A1CA4CA1
SCHEMBL29102439 0.71 PARP10 (0.37) LMNAGAAKMT2ATSHRALDH1A1
SCHEMBL4735958 0.69 CA4 (0.50) LMNATSHRLTA4HCA4CA1
SCHEMBL1162702 0.69 LTA4H (0.41) TSHRLTA4HALDH1A1CA4CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111788484-B Method for stabilizing protein contained in sample, solution for stabilizing protein contained in sample 荣研化学株式会社 2024-11-19 CN claimed
US-10155676-B2 Process for extracting a surfactant using a boronic acid modified material BICKER KEVIN L (US) 2018-12-18 US claimed
US-20170057840-A1 Process For Extracting A Surfactant Using A Boronic Acid Modified Material BICKER KEVIN L (US) 2017-03-02 US claimed
US-20120322145-A1 THREE-DIMENSIONAL CELL ADHESION MATRIX THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2012-12-20 US claimed
US-20120141384-A1 ANTIBACTERIAL CONJUGATED BORONIC ACIDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOAMIX PHARMACEUTICALS LTD. (IL) 2012-06-07 US claimed
WO-2010148346-A2 THREE-DIMENSIONAL CELL ADHESION MATRIX THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-12-23 WO claimed
US-20240228500-A1 THERAPEUTIC CONJUGATES TOTUS MEDICINES INC. 2024-07-11 US disclosed
US-12029791-B2 Therapeutic conjugates TOTUS MEDICINES INC. (US) 2024-07-09 US disclosed
WO-2024086664-A2 COVALENT INHIBITORS OF WILD-TYPE AND MUTANT PI3K AND METHOD OF USES THEREOF TOTUS MEDICINES INC. (US) 2024-04-25 WO disclosed
EP-4308121-A1 THERAPEUTIC CONJUGATES Totus Medicines Inc. (US) 2024-01-24 EP disclosed
US-20230405135-A1 THERAPEUTIC CONJUGATES TOTUS MEDICINES INC (US) 2023-12-21 US disclosed
WO-2023183936-A2 COMBINATION THERAPY OF A PI3K INHIBITOR AND KRAS INHIBITOR AND METHODS OF USE THEREOF TOTUS MEDICINES INC. (US) 2023-09-28 WO disclosed
EP-4210766-A1 THERAPEUTIC CONJUGATES Totus Medicines Inc. (US) 2023-07-19 EP disclosed
US-20070179131-A1 Novel M3 Muscarinic Acetylcholine Receptor Antagonists GLAXO GROUP LIMITED (GB) 2007-08-02 US disclosed
EP-1751089-A2 NOVEL M3 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS GLAXO GROUP LIMITED (GB) 2007-02-14 EP disclosed
EP-1725236-A1 NOVEL M3 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS GLAXO GROUP LIMITED (GB) 2006-11-29 EP disclosed
WO-2005087236-A1 NOVEL M3 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS GLAXO GROUP LIMITED (GB) 2005-09-22 WO disclosed
WO-2005086873-A2 NOVEL M3 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS GLAXO GROUP LIMITED (US) 2005-09-22 WO disclosed
EP-1140941-A1 NITROGEN CONTAINING HETEROBICYCLES AS FACTOR XA INHIBITORS Du Pont Pharmaceuticals Company (US) 2001-10-10 EP disclosed
WO-2000039131-A1 NITROGEN CONTAINING HETEROBICYCLES AS FACTOR XA INHIBITORS DU PONT PHARMACEUTICALS COMPANY (US) 2000-07-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070179131-A1 Novel M3 Muscarinic Acetylcholine Receptor Antagonists CHRM3, CHRM2, CHRNA3 LMNA 3932/4885GAA 4650/4885KMT2A 2049/4885
US-20120141384-A1 ANTIBACTERIAL CONJUGATED BORONIC ACIDS AND PHARMACEUTICAL COMPOSITIONS THEREOF ABCB11, SLC10A2, SLC10A1 LMNA 2718/4885GAA 25/4885KMT2A 3669/4885
US-12029791-B2 Therapeutic conjugates CD47, CD44, EPCAM LMNA 2481/4885GAA 348/4885KMT2A 2318/4885
US-20240228500-A1 THERAPEUTIC CONJUGATES CD47, CD44, EPCAM LMNA 2481/4885GAA 348/4885KMT2A 2318/4885
US-20230405135-A1 THERAPEUTIC CONJUGATES CD47, CD44, EPCAM LMNA 2481/4885GAA 348/4885KMT2A 2318/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.