SCHEMBL51175

SCHEMBL51175

CCC(CC#CC(=O)O)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA2 P00918 1/20 0.43
▸ MAPK1 P28482 1/20 0.43
▸ GRIK1 P39086 5/20 0.43
▸ GRIK2 Q13002 5/20 0.43
▸ SLC1A3 P43003 2/20 0.42
▸ SLC1A2 P43004 2/20 0.42
▸ SLC1A1 P43005 2/20 0.42
▸ TDP1 Q9NUW8 2/20 0.39
▸ CHRM1 P11229 1/20 0.39
▸ AKR1A1 P14550 1/20 0.39
▸ CHRM3 P20309 1/20 0.39
▸ HTR2A P28223 1/20 0.39
▸ HTR2C P28335 1/20 0.39
▸ ADRA1A P35348 1/20 0.39
▸ HRH1 P35367 1/20 0.39
▸ DRD3 P35462 1/20 0.39
▸ SLC6A3 Q01959 1/20 0.39
▸ HDAC1 Q13547 1/20 0.39
▸ HDAC2 Q92769 1/20 0.39
▸ GCLC P48506 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL576209 0.80 GRIK1 (0.60) CA2MAPK1GRIK1GRIK2SLC1A3
SCHEMBL265349 0.75 — —
SCHEMBL28212361 0.75 CA2 (0.67) CA2MAPK1GRIK1GRIK2SLC1A3
SCHEMBL27843743 0.75 — —
SCHEMBL7144191 0.75 — —
SCHEMBL2146877 0.73 — —
SCHEMBL3104177 0.73 — —
SCHEMBL6114 0.72 — —
SCHEMBL3101364 0.72 — —
Acetic Acid SCHEMBL18011985 0.71 CA2 (0.61) CA2MAPK1GRIK1GRIK2SLC1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 976 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9382205-B2 Processes for the manufacture of a pharmaceutically active agent H. LUNDBECK A/S (DK) 2016-07-05 — — US claimed
US-20150080584-A1 PROCESSES FOR THE MANUFACTURE OF A PHARMACEUTICALLY ACTIVE AGENT H. LUNDBECK A/S (DK) 2015-03-19 — — US claimed
US-20260144753-A1 MULTIVALENT IONIZABLE LIPID DELIVERY SYSTEMS FACTOR BIOSCIENCE INC. (US) 2026-05-28 — — US disclosed
WO-2026102133-A1 MULTIVALENT IONIZABLE LIPID DELIVERY SYSTEMS FACTOR BIOSCIENCE INC. (US) 2026-05-15 — — WO disclosed
US-20260124298-A1 CLEC9A BINDING AGENTS Orionis Biosciences BV (BE) 2026-05-07 — — US disclosed
US-20260125473-A1 CD8 BINDING AGENTS ORIONIS BIOSCIENCES INC (US) 2026-05-07 — — US disclosed
US-20260115254-A1 IMMUNE-CELL TARGETED BISPECIFIC CHIMERIC PROTEINS AND USES THEREOF VIB VZW (BE) 2026-04-30 — — US disclosed
US-20260109748-A1 MODULATION OF DENDRITIC CELL LINEAGES ORIONIS BIOSCIENCES INC (US) 2026-04-23 — — US disclosed
EP-3580230-B1 IMMUNE-CELL TARGETED BISPECIFIC CHIMERIC PROTEINS AND USES THEREOF VIB VZW (BE) 2026-04-22 — — EP disclosed
US-20260102512-A1 COMPOSITIONS AND METHODS RELATED TO MEGAKARYOCYTE-DERIVED EXTRACELLULAR VESICLES FOR FANCONI ANEMIA STRM BIO INCORPORATED (US) 2026-04-16 — — US disclosed
US-12583941-B2 Fibroblast activation protein binding agents and use thereof ORIONIS BIOSCIENCES, INC. (US) 2026-03-24 — — US disclosed
EP-0736007-A1 NON-PEPTIDE TACHYKININ RECEPTOR ANTAGONISTS ELI LILLY AND COMPANY (US) 1996-10-09 — — EP disclosed
EP-0716854-A2 Compositions for inhibiting neuropeptide y receptors ELI LILLY AND COMPANY (US) 1996-06-19 — — EP disclosed
WO-1996012489-A1 BICYCLIC NEUROPEPTIDE Y RECEPTOR ANTAGONISTS ELI LILLY AND COMPANY (US) 1996-05-02 — — WO disclosed
WO-1996012488-A1 BICYCLIC BRADYKININ RECEPTOR ANTAGONISTS ELI LILLY AND COMPANY (US) 1996-05-02 — — WO disclosed
EP-0709090-A2 Compositions for treating resistant tumors ELI LILLY AND COMPANY (US) 1996-05-01 — — EP disclosed
WO-1996011677-A1 METHODS FOR TREATING RESISTANT TUMORS ELI LILLY AND COMPANY (US) 1996-04-25 — — WO disclosed
EP-0707852-A2 Bicyclic bradykinin receptor antagonists ELI LILLY AND COMPANY (US) 1996-04-24 — — EP disclosed
WO-1995017095-A1 METHODS FOR THE TREATMENT OR PREVENTION OF CONDITIONS ASSOCIATED WITH AMYLOIDOGENIC REPTIDES ELI LILLY AND COMPANY (US) 1995-06-29 — — WO disclosed
WO-1995017382-A1 NON-PEPTIDE TACHYKININ RECEPTOR ANTAGONISTS ELI LILLY AND COMPANY (US) 1995-06-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12583941-B2 Fibroblast activation protein binding agents and use thereof FAP, IGSF11, FIBP CA2 3161/4885MAPK1 2512/4885GRIK1 4429/4885
US-20260115254-A1 IMMUNE-CELL TARGETED BISPECIFIC CHIMERIC PROTEINS AND USES THEREOF SCTR, CSF1R, MSR1 CA2 2693/4885MAPK1 1135/4885GRIK1 3721/4885
US-20150080584-A1 PROCESSES FOR THE MANUFACTURE OF A PHARMACEUTICALLY ACTIVE AGENT CEL, DCPS, HPSE CA2 2567/4885MAPK1 3121/4885GRIK1 4287/4885
US-20260109748-A1 MODULATION OF DENDRITIC CELL LINEAGES FCGR3B, VSIG8, TNFRSF9 CA2 3479/4885MAPK1 4232/4885GRIK1 3293/4885
US-20260144753-A1 MULTIVALENT IONIZABLE LIPID DELIVERY SYSTEMS PLTP, SLC7A1, PCTP CA2 1048/4885MAPK1 3963/4885GRIK1 3890/4885
US-20260102512-A1 COMPOSITIONS AND METHODS RELATED TO MEGAKARYOCYTE-DERIVED EXTRACELLULAR VESICLES FOR FANCONI ANEMIA CD47, CD63, LAMP1 CA2 4616/4885MAPK1 3262/4885GRIK1 3651/4885
US-20260125473-A1 CD8 BINDING AGENTS CD74, IGSF11, CD81 CA2 2311/4885MAPK1 3552/4885GRIK1 2123/4885
US-20260124298-A1 CLEC9A BINDING AGENTS TNFRSF9, SIGLEC9, IGSF11 CA2 3351/4885MAPK1 2116/4885GRIK1 590/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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