SCHEMBL51175

SCHEMBL51175

CCC(CC#CC(=O)O)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.43
MAPK1 P28482 1/20 0.43
GRIK1 P39086 5/20 0.43
GRIK2 Q13002 5/20 0.43
SLC1A3 P43003 2/20 0.42
SLC1A2 P43004 2/20 0.42
SLC1A1 P43005 2/20 0.42
TDP1 Q9NUW8 2/20 0.39
CHRM1 P11229 1/20 0.39
AKR1A1 P14550 1/20 0.39
CHRM3 P20309 1/20 0.39
HTR2A P28223 1/20 0.39
HTR2C P28335 1/20 0.39
ADRA1A P35348 1/20 0.39
HRH1 P35367 1/20 0.39
DRD3 P35462 1/20 0.39
SLC6A3 Q01959 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC2 Q92769 1/20 0.39
GCLC P48506 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL576209 0.80 GRIK1 (0.60) CA2MAPK1GRIK1GRIK2SLC1A3
SCHEMBL27843743 0.75
SCHEMBL265349 0.75
SCHEMBL28212361 0.75 CA2 (0.67) CA2MAPK1GRIK1GRIK2SLC1A3
SCHEMBL7144191 0.75
SCHEMBL3104177 0.73
SCHEMBL2146877 0.73
SCHEMBL6114 0.72
SCHEMBL3101364 0.72
Acetic Acid SCHEMBL18011985 0.71 CA2 (0.61) CA2MAPK1GRIK1GRIK2SLC1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 976 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9382205-B2 Processes for the manufacture of a pharmaceutically active agent H. LUNDBECK A/S (DK) 2016-07-05 US claimed
US-20150080584-A1 PROCESSES FOR THE MANUFACTURE OF A PHARMACEUTICALLY ACTIVE AGENT H. LUNDBECK A/S (DK) 2015-03-19 US claimed
US-20260144753-A1 MULTIVALENT IONIZABLE LIPID DELIVERY SYSTEMS FACTOR BIOSCIENCE INC. (US) 2026-05-28 US disclosed
WO-2026102133-A1 MULTIVALENT IONIZABLE LIPID DELIVERY SYSTEMS FACTOR BIOSCIENCE INC. (US) 2026-05-15 WO disclosed
US-20260124298-A1 CLEC9A BINDING AGENTS Orionis Biosciences BV (BE) 2026-05-07 US disclosed
US-20260125473-A1 CD8 BINDING AGENTS ORIONIS BIOSCIENCES INC (US) 2026-05-07 US disclosed
US-20260115254-A1 IMMUNE-CELL TARGETED BISPECIFIC CHIMERIC PROTEINS AND USES THEREOF VIB VZW (BE) 2026-04-30 US disclosed
US-20260109748-A1 MODULATION OF DENDRITIC CELL LINEAGES ORIONIS BIOSCIENCES INC (US) 2026-04-23 US disclosed
EP-3580230-B1 IMMUNE-CELL TARGETED BISPECIFIC CHIMERIC PROTEINS AND USES THEREOF VIB VZW (BE) 2026-04-22 EP disclosed
US-20260102512-A1 COMPOSITIONS AND METHODS RELATED TO MEGAKARYOCYTE-DERIVED EXTRACELLULAR VESICLES FOR FANCONI ANEMIA STRM BIO INCORPORATED (US) 2026-04-16 US disclosed
US-12583941-B2 Fibroblast activation protein binding agents and use thereof ORIONIS BIOSCIENCES, INC. (US) 2026-03-24 US disclosed
EP-0736007-A1 NON-PEPTIDE TACHYKININ RECEPTOR ANTAGONISTS ELI LILLY AND COMPANY (US) 1996-10-09 EP disclosed
EP-0716854-A2 Compositions for inhibiting neuropeptide y receptors ELI LILLY AND COMPANY (US) 1996-06-19 EP disclosed
WO-1996012489-A1 BICYCLIC NEUROPEPTIDE Y RECEPTOR ANTAGONISTS ELI LILLY AND COMPANY (US) 1996-05-02 WO disclosed
WO-1996012488-A1 BICYCLIC BRADYKININ RECEPTOR ANTAGONISTS ELI LILLY AND COMPANY (US) 1996-05-02 WO disclosed
EP-0709090-A2 Compositions for treating resistant tumors ELI LILLY AND COMPANY (US) 1996-05-01 EP disclosed
WO-1996011677-A1 METHODS FOR TREATING RESISTANT TUMORS ELI LILLY AND COMPANY (US) 1996-04-25 WO disclosed
EP-0707852-A2 Bicyclic bradykinin receptor antagonists ELI LILLY AND COMPANY (US) 1996-04-24 EP disclosed
WO-1995017095-A1 METHODS FOR THE TREATMENT OR PREVENTION OF CONDITIONS ASSOCIATED WITH AMYLOIDOGENIC REPTIDES ELI LILLY AND COMPANY (US) 1995-06-29 WO disclosed
WO-1995017382-A1 NON-PEPTIDE TACHYKININ RECEPTOR ANTAGONISTS ELI LILLY AND COMPANY (US) 1995-06-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12583941-B2 Fibroblast activation protein binding agents and use thereof FAP, IGSF11, FIBP CA2 3161/4885MAPK1 2512/4885GRIK1 4429/4885
US-20260115254-A1 IMMUNE-CELL TARGETED BISPECIFIC CHIMERIC PROTEINS AND USES THEREOF SCTR, CSF1R, MSR1 CA2 2693/4885MAPK1 1135/4885GRIK1 3721/4885
US-20150080584-A1 PROCESSES FOR THE MANUFACTURE OF A PHARMACEUTICALLY ACTIVE AGENT CEL, DCPS, HPSE CA2 2567/4885MAPK1 3121/4885GRIK1 4287/4885
US-20260109748-A1 MODULATION OF DENDRITIC CELL LINEAGES FCGR3B, VSIG8, TNFRSF9 CA2 3479/4885MAPK1 4232/4885GRIK1 3293/4885
US-20260144753-A1 MULTIVALENT IONIZABLE LIPID DELIVERY SYSTEMS PLTP, SLC7A1, PCTP CA2 1048/4885MAPK1 3963/4885GRIK1 3890/4885
US-20260102512-A1 COMPOSITIONS AND METHODS RELATED TO MEGAKARYOCYTE-DERIVED EXTRACELLULAR VESICLES FOR FANCONI ANEMIA CD47, CD63, LAMP1 CA2 4616/4885MAPK1 3262/4885GRIK1 3651/4885
US-20260125473-A1 CD8 BINDING AGENTS CD74, IGSF11, CD81 CA2 2311/4885MAPK1 3552/4885GRIK1 2123/4885
US-20260124298-A1 CLEC9A BINDING AGENTS TNFRSF9, SIGLEC9, IGSF11 CA2 3351/4885MAPK1 2116/4885GRIK1 590/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.