Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 15/20 | 0.45 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL98484 | 0.89 | LMNA (0.39) | FDPSGGPS1LPAR1LPAR3LMNA | |
| SCHEMBL385677 | 0.71 | LMNA (0.33) | LMNA | |
| SCHEMBL1238007 | 0.70 | FDPS (0.37) | FDPSGGPS1SMPD1LPAR1LPAR3 | |
| SCHEMBL10965541 | 0.69 | ACHE (0.42) | LPAR1LPAR3LMNA | |
| SCHEMBL9459028 | 0.69 | CASP1 (0.31) | — | |
| SCHEMBL29155304 | 0.69 | FDPS (0.36) | FDPSGGPS1SMPD1LPAR1LPAR3 | |
| SCHEMBL1443715 | 0.69 | FDPS (0.52) | FDPSGGPS1SMPD1LPAR1LPAR3 | |
| SCHEMBL3895417 | 0.67 | FDPS (0.56) | FDPSGGPS1SMPD1LPAR1LPAR3 | |
| SCHEMBL11151927 | 0.67 | FDPS (0.34) | FDPSGGPS1LMNA | |
| SCHEMBL27783191 | 0.67 | FDPS (0.40) | FDPSGGPS1SMPD1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3550321-A1 | MATERIALS WITH HIGH DIELECTRIC CONSTANT FOR MAGNETIC RESONANCE IMAGING INSTRUMENTS | Centre National de la Recherche Scientifique (CNRS) (FR) | 2019-10-09 | — | — | EP | disclosed |
| US-9090539-B2 | Compounds and methods for preparing substituted 3-(1-amino-2-methylpentane-3-yl)phenyl compounds | AMPAC FINE CHEMICALS LLC (US) | 2015-07-28 | — | — | US | disclosed |
| US-20140350283-A1 | Compounds and Methods for Preparing Substituted 3-(1-amino-2-methylpentane-3-yl)phenyl Compounds | AMPAC FINE CHEMICALS LLC | 2014-11-27 | — | — | US | disclosed |
| US-6855836-B2 | 17-Methylene steroids, process for their production and pharmaceutical compositions that contain these compounds | JENAPHARM GMBH & CO. KG (DE) | 2005-02-15 | — | — | US | disclosed |
| US-20020091112-A1 | 17-methylene steroids, process for their production and pharmaceutical compositions that contain these compounds | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2002-07-11 | — | — | US | disclosed |
| US-6376512-B1 | FOR TREATING PHYSIOLOGICAL CONDITION IN PATIENT WHEREIN SAID CONDITION IS ASSOCIATED WITH A PHYSIOLOGICALLY DETRIMENTAL LEVELS OF INSULIN, GLUCOSE, FREE FATTY ACIDS, OR TRIGLYCERIDES | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-04-23 | — | — | US | disclosed |
| EP-0315399-B1 | Quinoline derivatives, their use in the treatment of hypersensitive ailments and a pharmaceutical composition containing the same | RHONE POULENC RORER INT (US) | 1996-01-10 | — | — | EP | disclosed |
| US-5059610-A | QUINOLINE DERIVATIVES AND THEIR USE AS ANTAGONISTS OF LEUKOTRIENE D4 | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1991-10-22 | — | — | US | disclosed |
| US-4920132-A | Quinoline derivatives and use thereof as antagonists of leukotriene D4 | RORER PHARMACEUTICAL CORP. (US) | 1990-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140350283-A1 | Compounds and Methods for Preparing Substituted 3-(1-amino-2-methylpentane-3-yl)phenyl Compounds | QDPR, SRMS, SPR | FDPS 81/4885GGPS1 68/4885SMPD1 2835/4885 |
| US-20020091112-A1 | 17-methylene steroids, process for their production and pharmaceutical compositions that contain these compounds | CYP17A1, HSD17B11, CYP19A1 | FDPS 111/4885GGPS1 141/4885SMPD1 1817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.