SCHEMBL5134879

SCHEMBL5134879

CNN(C)NC(=O)CC(C)=O

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
HTT P42858 2/20 0.32
LMNA P02545 1/20 0.32
PHF8 Q9UPP1 2/20 0.32
KDM2A Q9Y2K7 2/20 0.32
KDM7A Q6ZMT4 1/20 0.32
MAPT P10636 1/20 0.31
KDM4E B2RXH2 1/20 0.30
KDM6B O15054 1/20 0.30
KDM5C P41229 1/20 0.30
EGLN1 Q9GZT9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4449362 0.77 PHF8 (0.52) MGAMGAASIMGAM2HTT
SCHEMBL7073065 0.71 HSP90AA1 (0.36) MGAMGAASIMGAM2HTT
SCHEMBL7622688 0.68 KDM4E (0.38) MGAMGAASIMGAM2HTT
SCHEMBL260075 0.68
SCHEMBL4379108 0.67 ALDH1A1 (0.33) KDM4E
SCHEMBL8520018 0.67 LMNA (0.36) MGAMGAASIMGAM2HTT
SCHEMBL31331896 0.66
SCHEMBL14890587 0.66 LMNA (0.42) MGAMGAASIMGAM2HTT
SCHEMBL8335018 0.66
SCHEMBL1401066 0.64 MGAM (0.45) MGAMGAASIMGAM2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9406834-B2 Material for forming passivation film for semiconductor substrate, passivation film for semiconductor substrate and method of producing the same, and photovoltaic cell element and method of producing the same HITACHI CHEMICAL COMPANY, LTD. (JP) 2016-08-02 US disclosed
US-20140242741-A1 MATERIAL FOR FORMING PASSIVATION FILM FOR SEMICONDUCTOR SUBSTRATE, PASSIVATION FILM FOR SEMICONDUCTOR SUBSTRATE AND METHOD OF PRODUCING THE SAME, AND PHOTOVOLTAIC CELL ELEMENT AND METHOD OF PRODUCING THE SAME HITACHI CHEMICAL COMPANY, LTD. (JP) 2014-08-28 US disclosed
US-8748877-B2 Material for forming passivation film for semiconductor substrate, passivation film for semiconductor substrate and method of producing the same, and photovoltaic cell element and method of producing the same HITACHI CHEMICAL COMPANY, LTD. (JP) 2014-06-10 US disclosed
US-20120313199-A1 MATERIAL FOR FORMING PASSIVATION FILM FOR SEMICONDUCTOR SUBSTRATE, PASSIVATION FILM FOR SEMICONDUCTOR SUBSTRATE AND METHOD OF PRODUCING THE SAME, AND PHOTOVOLTAIC CELL ELEMENT AND METHOD OF PRODUCING THE SAME HITACHI CHEMICAL COMPANY, LTD. 2012-12-13 US disclosed
US-20120196206-A1 METHOD FOR PRODUCING STRONGLY ACIDIC ZIRCONIUM PARTICLES, PROTON CONDUCTING MATERIAL, METHOD FOR PRODUCING PROTON CONDUCTING MEMBRANE, PROTON CONDUCTING MEMBRANE, ELECTRODE FOR FUEL CELL, MEMBRANE ELECTRODE ASSEMBLY, FUEL CELL TOKYO INSTITUTE OF TECHNOLOGY (JP) 2012-08-02 US disclosed
EP-2465863-A1 METHOD FOR PRODUCING STRONGLY ACIDIC ZIRCONIUM PARTICLES, METHOD FOR PRODUCING PROTON CONDUCTING MATERIAL AND PROTON CONDUCTING FILM, PROTON CONDUCTING FILM, ELECTRODE FOR FUEL CELL, FILM-ELECTRODE JOINED BODY, FUEL CELL Tokyo Institute of Technology (JP) 2012-06-20 EP disclosed
US-7371480-B2 Silica sol composition, membrane electrode assembly with proton-exchange membrane, and fuel cell FUJIFILM CORPORATION (JP) 2008-05-13 US disclosed
US-20040241522-A1 Silica sol composition, membrane electrode assembly with proton-exchange membrane, and fuel cell FUJI PHOTO FILM CO., LTD. 2004-12-02 US disclosed
EP-1463140-A2 Silica sol composition, membrane electrode assembly with proton-exchange membrane, and fuel cell Fuji Photo Film Co. Ltd. (JP) 2004-09-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120196206-A1 METHOD FOR PRODUCING STRONGLY ACIDIC ZIRCONIUM PARTICLES, PROTON CONDUCTING MATERIAL, METHOD FOR PRODUCING PROTON CONDUCTING MEMBRANE, PROTON CONDUCTING MEMBRANE, ELECTRODE FOR FUEL CELL, MEMBRANE ELECTRODE ASSEMBLY, FUEL CELL PHOSPHO1, NSF, HVCN1 MGAM 1877/4885GAA 2679/4885SI 183/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.