SCHEMBL514156

SCHEMBL514156

C1=CC2c3ccccc3/C=C\C=C/N2C=C1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ BRD4 O60885 1/20 0.34
▸ CCL2 P13500 1/20 0.34
▸ HTR2A P28223 2/20 0.33
▸ KDM4E B2RXH2 2/20 0.31
▸ LMNA P02545 1/20 0.31
▸ TP53 P04637 1/20 0.31
▸ CHRM2 P08172 1/20 0.31
▸ CYP3A4 P08684 1/20 0.31
▸ CYP2D6 P10635 1/20 0.31
▸ CHRM1 P11229 1/20 0.31
▸ DRD2 P14416 1/20 0.31
▸ ADRA2B P18089 1/20 0.31
▸ ADRA2C P18825 1/20 0.31
▸ NFKB1 P19838 1/20 0.31
▸ CHRM3 P20309 1/20 0.31
▸ SLC6A2 P23975 1/20 0.31
▸ HTR2C P28335 1/20 0.31
▸ ADRA1A P35348 1/20 0.31
▸ HRH1 P35367 1/20 0.31
▸ DRD3 P35462 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL418352 0.93 BRD4 (0.38) BRD4CCL2HTR2AKDM4ELMNA
SCHEMBL11348748 0.79 BRD4 (0.41) BRD4CCL2HTR2AKDM4ELMNA
SCHEMBL18814602 0.73 — —
SCHEMBL18516527 0.73 FAAH (0.31) —
SCHEMBL10390576 0.73 BRD4 (0.41) BRD4CCL2HTR2AKDM4ELMNA
SCHEMBL517047 0.69 — —
SCHEMBL15615571 0.68 DRD2 (0.30) DRD2
SCHEMBL24896198 0.68 HTR2A (0.38) BRD4CCL2HTR2AKDM4ELMNA
SCHEMBL7772311 0.68 HTR2A (0.38) BRD4CCL2HTR2AKDM4ELMNA
SCHEMBL8330852 0.67 HTR2A (0.36) BRD4CCL2HTR2AKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 797 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4702032-A1 MODIFICATION OF PSEUDOURIDINE Ludwig Institute for Cancer Research Ltd (CH) 2026-03-04 — — EP claimed
US-20260034238-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME GENMAB AS (DK) 2026-02-05 — — US claimed
US-20260034237-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME GENMAB AS (DK) 2026-02-05 — — US claimed
US-12527871-B2 Click chemistry capturable platinum-based antineoplastic agents BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-01-20 — — US claimed
US-20250376724-A1 LINEAR DOUBLE STRANDED DNA COUPLED TO A SINGLE SUPPORT OR A TAG AND METHODS FOR PRODUCING SAID LINEAR DOUBLE STRANDED DNA CureVac SE (DE) 2025-12-11 — — US claimed
EP-4648800-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME Genmab A/S (DK) 2025-11-19 — — EP claimed
EP-4648801-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME Genmab A/S (DK) 2025-11-19 — — EP claimed
EP-4642491-A1 METHOD FOR GLYCOPROTEIN MODIFICATION Honeybear Biosciences Inc. (TW) 2025-11-05 — — EP claimed
US-20250289846-A1 METHODS OF PURIFYING ANTIBODY-NUCLEIC ACID CONJUGATES BRUKER SPATIAL BIOLOGY, INC. 2025-09-18 — — US claimed
US-20250288685-A1 BIOMATERIALS FOR IMPROVING BRAIN HEALING AFTER STROKE AND METHODS OF USING SAME UNIV DUKE (US) 2025-09-18 — — US claimed
WO-2017218891-A1 SITE-SPECIFIC CROSSLINKING OF ANTIBODIES Life Technologies Corporation (US) 2017-12-21 — — WO claimed
WO-2017212329-A1 CLIPTAC COMPOSITION OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2017-12-14 — — WO claimed
US-20170312363-A1 MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2017-11-02 — — US claimed
EP-3204425-A2 GLYCOENGINEERED ANTIBODY DRUG CONJUGATES Genzyme Corporation (US) 2017-08-16 — — EP claimed
US-20170216460-A1 GLYCOPEPTIDE FOR CONTRAST AGENT TARGETING CANCER CELLS AND CONTRAST AGENT KIT CONTAINING THE SAME KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2017-08-03 — — US claimed
WO-2016191556-A1 LIPOSOMAL NANOCONSTRUCTS AND METHODS OF MAKING AND USING THE SAME THE GENERAL HOSPITAL CORPORATION (US) 2016-12-01 — — WO claimed
WO-2016183387-A1 COMPOSITIONS AND METHODS FOR MAKING ANTIBODY CONJUGATES THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2016-11-17 — — WO claimed
US-20160136299-A1 GLYCOENGINEERED ANTIBODY DRUG CONJUGATES GENZYME CORPORATION 2016-05-19 — — US claimed
WO-2016057769-A2 GLYCOENGINEERED ANTIBODY DRUG CONJUGATES GENZYME CORPORATION (US) 2016-04-14 — — WO claimed
US-20130281656-A1 METHODS FOR LABELING A SUBSTRATE HAVING A PLURALITY OF THIOL GROUPS ATTACHED THERETO UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. BOYD GRADUATE STUDIES RESEARCH CENTER (US) 2013-10-24 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130281656-A1 METHODS FOR LABELING A SUBSTRATE HAVING A PLURALITY OF THIOL GROUPS ATTACHED THERETO SQOR, NQO2, DAO BRD4 3825/4885CCL2 3281/4885HTR2A 2249/4885
US-20260034237-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME CSGALNACT1, SLC43A1, OSTC BRD4 2631/4885CCL2 1305/4885HTR2A 2014/4885
US-20160136299-A1 GLYCOENGINEERED ANTIBODY DRUG CONJUGATES CD2BP2, B3GAT3, SIGLEC7 BRD4 4347/4885CCL2 564/4885HTR2A 4624/4885
US-12527871-B2 Click chemistry capturable platinum-based antineoplastic agents LPXN, ILK, PDCD10 BRD4 2045/4885CCL2 56/4885HTR2A 4304/4885
US-20260034238-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME MGAT3, GALE, GPI BRD4 1008/4885CCL2 1336/4885HTR2A 4543/4885
US-20170312363-A1 MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR HDGF, F11, F12 BRD4 4053/4885CCL2 2477/4885HTR2A 4486/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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