Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL812717 | 0.85 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2KMT2AKDM4ELMNA | |
| Ammonia Solution, Strong SCHEMBL16781743 | 0.82 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2KMT2AKDM4ELMNA | |
| SCHEMBL28443362 | 0.77 | POLB (0.41) | ALDH1A1SMN1; SMN2KMT2AKDM4ELMNA | |
| SCHEMBL2986829 | 0.77 | KMT2A (0.46) | ALDH1A1SMN1; SMN2KMT2AKDM4ELMNA | |
| SCHEMBL95282 | 0.72 | — | — | |
| SCHEMBL14846126 | 0.72 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2KMT2AKDM4ELMNA | |
| SCHEMBL1145440 | 0.72 | — | — | |
| SCHEMBL18663864 | 0.72 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2KMT2AKDM4ELMNA | |
| SCHEMBL14259069 | 0.72 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2KMT2AKDM4ELMNA | |
| SCHEMBL5890646 | 0.71 | KDM4E (0.52) | ALDH1A1SMN1; SMN2KMT2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5721350-A | Deuterated nucleosides | CHATTOPADHYAYA JYOTI (SE) | 1998-02-24 | — | — | US | claimed |
| WO-1993025566-A1 | DEUTERATED NUCLEOSIDES | CHATTOPADHYAYA JYOTI (SE) | 1993-12-23 | — | — | WO | claimed |
| US-20240018180-A1 | OLIGONUCLEOTIDE PRODUCTION METHOD | AJINOMOTO CO., INC. (JP) | 2024-01-18 | — | — | US | disclosed |
| EP-4293035-A1 | OLIGONUCLEOTIDE PRODUCTION METHOD | AJINOMOTO CO., INC. (JP) | 2023-12-20 | — | — | EP | disclosed |
| WO-2023210623-A1 | HALOALKYL SULFONE ANILIDE COMPOUND AND HERBICIDE CONTAINING SAME | 株式会社エス・ディー・エス バイオテック | 2023-11-02 | — | — | WO | disclosed |
| US-9273149-B2 | Methods and compositions for determining the purity of chemically synthesized nucleic acids | VERI-Q, INC. (US) | 2016-03-01 | — | — | US | disclosed |
| EP-2276775-B1 | PROCESS FOR THE MANUFACTURE OF OLIGONUCLEOTIDES | NITTO DENKO AVECIA INC (US) | 2015-09-02 | — | — | EP | disclosed |
| WO-2014184070-A1 | MIXTURES OF HALOALKYLSULFONANILIDE DERIVATIVES AND HERBICIDES | SYNGENTA LIMITED (GB) | 2014-11-20 | — | — | WO | disclosed |
| WO-2014184071-A1 | MIXTURES OF HALOALKYLSULFONANILIDE DERIVATIVES AND HERBICIDES | SYNGENTA LIMITED (GB) | 2014-11-20 | — | — | WO | disclosed |
| US-20140193855-A1 | METHODS AND COMPOSITIONS FOR DETERMINING THE PURITY OF CHEMICALLY SYNTHESIZED NUCLEIC ACIDS | VERI-Q, INC. (US) | 2014-07-10 | — | — | US | disclosed |
| US-8697355-B2 | Methods and compositions for determining the purity of chemically synthesized nucleic acids | NORTH CAROLINA STATE UNIVERSITY (US) | 2014-04-15 | — | — | US | disclosed |
| EP-1412752-A1 | METHODS AND COMPOSITIONS FOR DETERMINING THE PURITY OF AND PURIFYING CHEMICALLY SYNTHESIZED NUCLEIC ACIDS | VERI-Q, Inc. (US) | 2004-04-28 | — | — | EP | disclosed |
| US-20030044831-A1 | Antibody for use in the generation and protection of preferential nucleotide sequences | AGRIS PAUL F (US) | 2003-03-06 | — | — | US | disclosed |
| WO-2003003014-A1 | METHODS AND COMPOSITIONS FOR DETERMINING THE PURITY OF AND PURIFYING CHEMICALLY SYNTHESIZED NUCLEIC ACIDS | VERI-Q, INC. (US) | 2003-01-09 | — | — | WO | disclosed |
| EP-1242459-A1 | METHODS AND COMPOSITIONS FOR DETERMINING THE PURITY OF CHEMICALLY SYNTHESIZED NUCLEIC ACIDS | NORTH CAROLINA STATE UNIVERSITY (US) | 2002-09-25 | — | — | EP | disclosed |
| US-20020051994-A1 | Synthesis of oligonucleotides | KWIATKOWSKI MAREK (SE) | 2002-05-02 | — | — | US | disclosed |
| US-20020045167-A1 | Used for detecting incomplete deprotection of a synthetic oligonucleotide by immunoassay | VERI-Q, INC. | 2002-04-18 | — | — | US | disclosed |
| US-6313284-B1 | Solid phase synthesis | MAREK KWIATKOWSKI (SE) | 2001-11-06 | — | — | US | disclosed |
| WO-2001049745-A9 | METHODS AND COMPOSITIONS FOR DETERMINING THE PURITY OF CHEMICALLY SYNTHESIZED NUCLEIC ACIDS | UNIV NORTH CAROLINA STATE (US) | 2001-09-20 | — | — | WO | disclosed |
| WO-2001049745-A1 | METHODS AND COMPOSITIONS FOR DETERMINING THE PURITY OF CHEMICALLY SYNTHESIZED NUCLEIC ACIDS | NORTH CAROLINA STATE UNIVERSITY (US) | 2001-07-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020051994-A1 | Synthesis of oligonucleotides | RNGTT, POLR2H, POLR2E | ALDH1A1 4690/4885SMN1; SMN2 1547/4885KMT2A 1123/4885 |
| US-20140193855-A1 | METHODS AND COMPOSITIONS FOR DETERMINING THE PURITY OF CHEMICALLY SYNTHESIZED NUCLEIC ACIDS | RNGTT, NOP2, DCLRE1B | ALDH1A1 4333/4885SMN1; SMN2 1955/4885KMT2A 2366/4885 |
| US-20030044831-A1 | Antibody for use in the generation and protection of preferential nucleotide sequences | CD2BP2, IGSF11, RNGTT | ALDH1A1 4659/4885SMN1; SMN2 2424/4885KMT2A 2667/4885 |
| US-20240018180-A1 | OLIGONUCLEOTIDE PRODUCTION METHOD | RNGTT, NOX4, POLRMT | ALDH1A1 1227/4885SMN1; SMN2 1937/4885KMT2A 2534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.