SCHEMBL5146471

SCHEMBL5146471

[Al+3].[H-].[H-].[H-].[H-].[H-].[H-].[Na+].[Na+].[Na+]

nearest known ligand 0.00

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL127310 1.00
SCHEMBL10590363 1.00
SCHEMBL15397579 1.00
Lithium Ion SCHEMBL8137212 0.87
SCHEMBL7641097 0.87
SCHEMBL31122202 0.82
SCHEMBL43332 0.82
SCHEMBL3408563 0.82
SCHEMBL2143055 0.82
SCHEMBL208 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6444190-B2 SLURRY OF A SODIUM ALUMINUM HYDRIDE, LITHIUM OR TITANIUM CONTAINING ADDITIVE AND A LEWIS BASE IN SOLVENT; NON-PYROPHORIC; THERMAL STABILITY FMC CORPORATION 2002-09-03 US claimed
US-20010051729-A1 NOVEL REDUCTION COMPOSITIONS AND PROCESSES FOR MAKING THE SAME FMC CORPORATION 2001-12-13 US claimed
WO-1998013319-A1 NOVEL REDUCTION COMPOSITIONS AND PROCESSES FOR MAKING THE SAME FMC CORPORATION (US) 1998-04-02 WO claimed
US-4512966-A Hydride production at moderate pressure ETHYL CORPORATION (US) 1985-04-23 US claimed
US-4010248-A FROM ALKALI METAL, ALUMINUM, AND HYDROGEN, ALKALI METAL ALUMINUM DIHYDROCARBON DIHYDRIDE CATALYST ETHYL CORPORATION (US) 1977-03-01 US claimed
US-20070178042-A1 Sodium Alanate Hydrogen Storage Material GM GLOBAL TECHNOLOGY OPERATIONS, INC. (US) 2007-08-02 US disclosed
US-6444190-B2 SLURRY OF A SODIUM ALUMINUM HYDRIDE, LITHIUM OR TITANIUM CONTAINING ADDITIVE AND A LEWIS BASE IN SOLVENT; NON-PYROPHORIC; THERMAL STABILITY FMC CORPORATION 2002-09-03 US disclosed
US-20010051729-A1 NOVEL REDUCTION COMPOSITIONS AND PROCESSES FOR MAKING THE SAME FMC CORPORATION 2001-12-13 US disclosed
WO-1998013319-A1 NOVEL REDUCTION COMPOSITIONS AND PROCESSES FOR MAKING THE SAME FMC CORPORATION (US) 1998-04-02 WO disclosed
EP-0600266-B1 Process for the preparation of SiH groups-containing organopolysiloxanes GOLDSCHMIDT AG TH (DE) 1996-01-10 EP disclosed
US-5371161-A Reacting an organopolysiloxane containing silicon halide groups with a metal hydride TH. GOLDSCHMIDT AG (DE) 1994-12-06 US disclosed
EP-0600266-A2 Process for the preparation of SiH groups-containing organopolysiloxanes Th. Goldschmidt AG (DE) 1994-06-08 EP disclosed
US-5136046-A Preparation of amine alanes ETHYL CORPORATION (US) 1992-08-04 US disclosed
EP-0266633-B1 PROCESS FOR THE PREPARATION OF ORGANOPOLYSILOXANES CONTAINING SIH-BONDS Th. Goldschmidt AG (DE) 1992-03-11 EP disclosed
US-4816541-A METAL HYDRIDES REACTED WITH HALOGEN TERMINATED POLYSILOXANES TH. GOLDSCHMIDT AG (DE) 1989-03-28 US disclosed
EP-0266633-A2 Process for the preparation of organopolysiloxanes containing SiH-bonds Th. Goldschmidt AG (DE) 1988-05-11 EP disclosed
US-4512966-A Hydride production at moderate pressure ETHYL CORPORATION (US) 1985-04-23 US disclosed
US-4010248-A FROM ALKALI METAL, ALUMINUM, AND HYDROGEN, ALKALI METAL ALUMINUM DIHYDROCARBON DIHYDRIDE CATALYST ETHYL CORPORATION (US) 1977-03-01 US disclosed
US-3983150-A Method of manufacture of N-alkyliminoalanes CESKOSLOVENSKA AKADEMIE VED (CS) 1976-09-28 US disclosed