Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | RGS12 | O14924 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1831826 | 0.98 | ALOX15 (0.49) | ALOX15KMT2AALDH1A1NPSR1APAF1 | |
| Iodide SCHEMBL30731330 | 0.96 | ALOX15 (0.50) | ALOX15KMT2AALDH1A1NPSR1APAF1 | |
| Water SCHEMBL21824327 | 0.96 | ALOX15 (0.47) | ALOX15KMT2AALDH1A1NPSR1APAF1 | |
| Iodide SCHEMBL1744004 | 0.96 | ALOX15 (0.50) | ALOX15KMT2AALDH1A1NPSR1APAF1 | |
| Bromide SCHEMBL9327194 | 0.96 | ALOX15 (0.47) | ALOX15KMT2AALDH1A1NPSR1APAF1 | |
| Formic Acid SCHEMBL29271990 | 0.87 | ALOX15 (0.45) | ALOX15KMT2AALDH1A1NPSR1APAF1 | |
| Bicarbonate SCHEMBL17911350 | 0.85 | ALOX15 (0.41) | ALOX15KMT2AALDH1A1NPSR1APAF1 | |
| Bicarbonate SCHEMBL29765381 | 0.85 | ALOX15 (0.44) | ALOX15KMT2AALDH1A1NPSR1APAF1 | |
| SCHEMBL13640709 | 0.84 | RAB9A (0.50) | ALOX15KMT2AALDH1A1NPSR1APAF1 | |
| Sulfuric Acid SCHEMBL6068895 | 0.84 | LMNA (0.44) | ALOX15KMT2AALDH1A1NPSR1APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12291506-B2 | Method for producing amidate compound, and amidate compound | KOEI CHEMICAL COMPANY, LIMITED (JP) | 2025-05-06 | — | — | US | disclosed |
| CN-118290346-A | Method for producing amide compound, and amide compound | 广荣化学株式会社 | 2024-07-05 | — | — | CN | disclosed |
| CN-112703184-B | Method for producing amide compound, and amide compound | 广荣化学株式会社 | 2024-06-11 | — | — | CN | disclosed |
| US-20220048864-A1 | METHOD FOR PRODUCING AMIDATE COMPOUND, AND AMIDATE COMPOUND | KOEI CHEMICAL COMPANY, LIMITED (JP) | 2022-02-17 | — | — | US | disclosed |
| EP-3858817-A1 | METHOD FOR PRODUCING AMIDATE COMPOUND, AND AMIDATE COMPOUND | Koei Chemical Company, Limited (JP) | 2021-08-04 | — | — | EP | disclosed |
| US-7273953-B2 | Process for producing arylamine | FUJIFILM FINECHEMICALS CO., LTD. (JP) | 2007-09-25 | — | — | US | disclosed |
| US-20060069287-A1 | Process for producing arylamine | FUJIFILM FINECHEMICALS CO., LTD. (JP) | 2006-03-30 | — | — | US | disclosed |
| EP-0404188-B1 | Non-aqueous electrolytic aluminum plating bath composition | NISSHIN STEEL CO LTD (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-5074973-A | Mixed melt containing aluminum halide, nitrogen-heterocyclic halides, additives, organic polymer | NISSHIN STEEL CO. LTD. (JP) | 1991-12-24 | — | — | US | disclosed |
| EP-0404188-A1 | Non-aqueous electrolytic aluminum plating bath composition | NISSHIN STEEL CO., LTD. (JP) | 1990-12-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060069287-A1 | Process for producing arylamine | TYR, AADAC, AOC2 | ALOX15 3266/4885KMT2A 352/4885ALDH1A1 747/4885 |
| US-12291506-B2 | Method for producing amidate compound, and amidate compound | NAAA, NIT2, PAM | ALOX15 2539/4885KMT2A 4207/4885ALDH1A1 4082/4885 |
| US-20220048864-A1 | METHOD FOR PRODUCING AMIDATE COMPOUND, AND AMIDATE COMPOUND | NAAA, NIT2, PAM | ALOX15 2539/4885KMT2A 4207/4885ALDH1A1 4082/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.