Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1241402 | 0.91 | GAA (0.41) | KMT2AALDH1A1SMN1; SMN2GAAMEN1 | |
| SCHEMBL17053358 | 0.85 | HSD17B10 (0.36) | KMT2AALDH1A1SMN1; SMN2MEN1CHRM2 | |
| SCHEMBL17057486 | 0.85 | HSD17B10 (0.36) | KMT2AALDH1A1SMN1; SMN2MEN1CHRM2 | |
| SCHEMBL15518427 | 0.83 | HSD17B10 (0.39) | KMT2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL560792 | 0.83 | HSD17B10 (0.39) | KMT2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL437100 | 0.77 | LMNA (0.36) | KMT2AALDH1A1SMN1; SMN2GAAMEN1 | |
| SCHEMBL12238070 | 0.77 | LMNA (0.36) | KMT2AALDH1A1SMN1; SMN2GAAMEN1 | |
| SCHEMBL12038457 | 0.75 | CHRM5 (0.35) | CHRM5CHRM3 | |
| SCHEMBL14522328 | 0.75 | CHRM5 (0.35) | CHRM5CHRM3 | |
| SCHEMBL20750016 | 0.75 | KMT2A (0.41) | KMT2AALDH1A1GAAMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1588145-A4 | METHODS, MIXTURES, KITS AND COMPOSITIONS PERTAINING TO ANALYTE DETERMINATION | APPLERA CORP (US) | 2007-05-16 | — | — | EP | disclosed |
| EP-1701945-A1 | LABELING REAGENTS, LABELED ANALYTES, INCLUDING MIXTURES THEREOF, AND FRAGMENT IONS DERIVED THEREFROM AND METHODS FOR THE ANALYSIS THEREOF | Applera Corporation (US) | 2006-09-20 | — | — | EP | disclosed |
| EP-1588145-A2 | METHODS, MIXTURES, KITS AND COMPOSITIONS PERTAINING TO ANALYTE DETERMINATION | Applera Corporation (US) | 2005-10-26 | — | — | EP | disclosed |
| WO-2005068446-A1 | LABELING REAGENTS, LABELED ANALYTES, INCLUDING MIXTURES THEREOF, AND FRAGMENT IONS DERIVED THEREFROM AND METHODS FOR THE ANALYSIS THEREOF | APPLERA CORPORATION (US) | 2005-07-28 | — | — | WO | disclosed |
| WO-2004070352-A2 | METHODS, MIXTURES, KITS AND COMPOSITIONS PERTAINING TO ANALYTE DETERMINATION | APPLERA CORPORATION (US) | 2004-08-19 | — | — | WO | disclosed |