Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.60 |
| ▸ | NPC1 | O15118 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.51 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.50 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | CASR | P41180 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5153133 | 0.89 | TP53 (0.59) | RAB9ANPC1SMN1; SMN2HTTPOLB | |
| SCHEMBL5853228 | 0.86 | HTT (0.75) | RAB9ANPC1SMN1; SMN2HTTPTGER3 | |
| SCHEMBL5632774 | 0.85 | SMN1; SMN2 (0.62) | RAB9ANPC1SMN1; SMN2HTTPOLB | |
| SCHEMBL7166145 | 0.83 | PTGS2 (0.63) | RAB9ANPC1PTGS2NR1H4HPGD | |
| SCHEMBL5991743 | 0.83 | PTGS2 (0.63) | RAB9ANPC1POLBPTGS2NR1H4 | |
| SCHEMBL13329758 | 0.80 | ALDH1A1 (0.63) | SMN1; SMN2POLBPTGS2NR1H4ALDH1A1 | |
| SCHEMBL366747 | 0.79 | SMN1; SMN2 (0.74) | RAB9ANPC1SMN1; SMN2CXCR2MEN1 | |
| SCHEMBL5852186 | 0.78 | DDX3X (0.70) | RAB9ANPC1SMN1; SMN2HTTPOLB | |
| SCHEMBL11028218 | 0.78 | HTT (0.77) | RAB9ANPC1SMN1; SMN2HTTPOLB | |
| SCHEMBL27581406 | 0.77 | POLB (0.64) | RAB9ASMN1; SMN2HTTPOLBNR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070054909-A1 | VLA-4 inhibitor compounds | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070054909-A1 | VLA-4 inhibitor compounds | VCAM1, ITGB4, ICAM1 | RAB9A 1984/4885NPC1 3300/4885SMN1; SMN2 4245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.