Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.54 |
| ▸ | CXCL8 | P10145 | 5/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.50 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | ALB | P02768 | 1/20 | 0.50 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.50 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5991743 | 0.83 | PTGS2 (0.63) | ALDH1A1NR1H4PTGS2CXCL8L3MBTL1 | |
| SCHEMBL21504754 | 0.83 | L3MBTL1 (0.73) | ALDH1A1RECQLSMN1; SMN2L3MBTL1POLB | |
| SCHEMBL5153133 | 0.83 | TP53 (0.59) | SMN1; SMN2NR1H4PTGS2CXCL8AKR1B10 | |
| SCHEMBL31226210 | 0.82 | NR1H4 (0.59) | ALDH1A1NR1H4PTGS2CXCL8AKR1B10 | |
| SCHEMBL3054871 | 0.82 | NR1H4 (0.59) | ALDH1A1NR1H4PTGS2CXCL8AKR1B10 | |
| SCHEMBL1964864 | 0.82 | PTGS2 (0.60) | NR1H4PTGS2CXCL8AKR1B10UGT1A9 | |
| SCHEMBL7466732 | 0.81 | ALDH1A1 (0.66) | ALDH1A1RECQLSMN1; SMN2L3MBTL1POLB | |
| SCHEMBL9724473 | 0.80 | CXCL8 (0.57) | ALDH1A1NR1H4PTGS2CXCL8AKR1B10 | |
| SCHEMBL5151876 | 0.80 | RAB9A (0.60) | ALDH1A1SMN1; SMN2NR1H4PTGS2POLB | |
| SCHEMBL194382 | 0.79 | NR1H4 (0.56) | NR1H4PTGS2CXCL8AKR1B10UGT1A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100113371-A9 | Derivatives Of Pentose Monosaccharides As Anti-Inflammatory Compounds | RANBAXY LABORATORIES LIMITED INC. (IN) | 2010-05-06 | — | — | US | disclosed |
| US-20100113371-A9 | Derivatives Of Pentose Monosaccharides As Anti-Inflammatory Compounds | RANBAXY LABORATORIES LIMITED INC. (IN) | 2010-05-06 | — | — | US | disclosed |
| US-20090075909-A1 | Derivatives Of Pentose Monosaccharides As Anti-Inflammatory Compounds | RANBAXY LABORATORIES LIMITED INC. (IN) | 2009-03-19 | — | — | US | disclosed |
| US-20090075909-A1 | Derivatives Of Pentose Monosaccharides As Anti-Inflammatory Compounds | RANBAXY LABORATORIES LIMITED INC. (IN) | 2009-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090075909-A1 | Derivatives Of Pentose Monosaccharides As Anti-Inflammatory Compounds | HLA-DRB1, IL5, TNF | ALDH1A1 867/4885RECQL 4865/4885SMN1; SMN2 4524/4885 |
| US-20100113371-A9 | Derivatives Of Pentose Monosaccharides As Anti-Inflammatory Compounds | HLA-DRB1, IL5, TNF | ALDH1A1 867/4885RECQL 4865/4885SMN1; SMN2 4524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.