SCHEMBL515232

SCHEMBL515232

C=Cc1ccc(CN(CC(=O)O)CC(=O)O)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
MEP1B Q16820 2/20 0.40
TDP1 Q9NUW8 3/20 0.37
LMNA P02545 2/20 0.37
TSHR P16473 2/20 0.37
PSMD14 O00487 1/20 0.37
EYA2 O00167 1/20 0.37
APP P05067 1/20 0.37
ACE P12821 1/20 0.37
AGTR2 P50052 1/20 0.36
HDAC6 Q9UBN7 2/20 0.36
HDAC3 O15379 1/20 0.36
KDM4E B2RXH2 1/20 0.35
CHRM2 P08172 1/20 0.35
ADRA2A P08913 1/20 0.35
ALOX15 P16050 1/20 0.35
DRD1 P21728 1/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12545554 0.98 MEP1B (0.42) ALDH1A1MEP1BTDP1LMNATSHR
SCHEMBL5322399 0.93 TDP1 (0.45) TDP1LMNATSHREYA2APP
SCHEMBL9405391 0.91 CA1 (0.38) ALDH1A1MEP1BTDP1LMNAPSMD14
SCHEMBL17354914 0.91 PSMD14 (0.35) ALDH1A1MEP1BTDP1LMNATSHR
SCHEMBL14341631 0.88 NR1D1 (0.40) MEP1BHDAC6HDAC3CA1CA2
SCHEMBL13958014 0.84 LTA4H (0.44) TDP1AGTR2HDAC6HDAC3KDM4E
SCHEMBL18460451 0.84 KCNH2 (0.44) TDP1LMNATSHREYA2APP
SCHEMBL13958499 0.83 TDP1 (0.40) ALDH1A1MEP1BTDP1KDM4ECA1
SCHEMBL18493213 0.82 ALDH1A1 (0.55) ALDH1A1TDP1TSHRHDAC6HDAC3
SCHEMBL13958502 0.80 NR3C1 (0.43) ALDH1A1TDP1LMNATSHRPSMD14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12245591-B2 Templated antimicrobial microgels and methods of making and using the same THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) 2025-03-11 US claimed
CN-119472194-A Phenol-free positive photoresist stripping liquid and preparation method thereof 浙江尚能实业股份有限公司 2025-02-18 CN claimed
EP-2432588-B1 POROUS POLYMERIC SEPARATION MATERIAL BIOTAGE AB (SE) 2017-01-18 EP claimed
US-9023770-B2 Increasing fracture complexity in ultra-low permeable subterranean formation using degradable particulate HALLIBURTON ENERGY SERVICES, INC. (US) 2015-05-05 US claimed
EP-2670815-A1 INCREASING FRACTURE COMPLEXITY IN ULTRA-LOW PERMEABLE SUBTERRANEAN FORMATION USING DEGRADABLE PARTICULATE Halliburton Energy Services, Inc. (US) 2013-12-11 EP claimed
WO-2012104582-A1 INCREASING FRACTURE COMPLEXITY IN ULTRA-LOW PERMEABLE SUBTERRANEAN FORMATION USING DEGRADABLE PARTICULATE HALLIBURTON ENERGY SERVICES INC. (US) 2012-08-09 WO claimed
US-20120128842-A1 POROUS POLYMERIC SEPARATION MATERIAL BIOTAGE AB (SE) 2012-05-24 US claimed
EP-2432588-A1 POROUS POLYMERIC SEPARATION MATERIAL Biotage AB (SE) 2012-03-28 EP claimed
US-20110120712-A1 INCREASING FRACTURE COMPLEXITY IN ULTRA-LOW PERMEABLE SUBTERRANEAN FORMATION USING DEGRADABLE PARTICULATE HALLIBURTON ENERGY SERVICES, INC. (US) 2011-05-26 US claimed
US-20110089317-A1 Polarization Standards for Microscopy UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER AT FORTH WORTH (US) 2011-04-21 US claimed
US-7001963-B2 Cobalt imprinted polymer composition for selective removal of cobalt, process for preparation thereof, and process for removal of cobalt COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2006-02-21 US claimed
WO-2005063835-A1 COBALT IMPRINTED POLYMER COMPOSITION, PREPARATION AND USE THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2005-07-14 WO claimed
US-20050070677-A1 Cobalt imprinted polymer composition for selective removal of cobalt, process for preparation thereof, and process for removal of cobalt COUNCIL OF SCIENTIF AND INDUSTRIAL RESEARCH (IN) 2005-03-31 US claimed
US-20050070676-A1 Cobalt imprinted polymer composition for selective removal of cobalt, process for preparation thereof, and process for removal of cobalt COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2005-03-31 US claimed
EP-0873106-B1 USE OF METALLOFLUOROCOMPLEXES FOR DENTAL COMPOSITIONS MINNESOTA MINING & MFG (US) 2003-05-02 EP claimed
US-6391286-B1 CURABLE DENTAL COMPOSITION COMPRISING PREFORMED METAL COMPLEX AS FLUORIDE RELEASING MATERIAL 3M INNOVATIVE PROPERTIES COMPANY 2002-05-21 US claimed
US-6177513-B1 Method for evaluating artificial receptors TOSHIFUMI TAKEUCHI (JP) 2001-01-23 US claimed
WO-1998008585-A1 LEACHING OF METAL CHALCOGENIDE (SULFIDE-TYPE) MINERALS WITH OXIDIZING AND CHELATING AGENTS GEOCHEM TECHNOLOGIES, INC. (US) 1998-03-05 WO claimed
US-5310648-A Polymer-metal chelate compound CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1994-05-10 US claimed
US-4904354-A IMPROVED ADHESION LEARONAL INC. (US) 1990-02-27 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12245591-B2 Templated antimicrobial microgels and methods of making and using the same MGAM, CD14, CD68 ALDH1A1 3189/4885MEP1B 1489/4885TDP1 4158/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.