Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 known ✓ | P35354 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28730236 | 0.96 | CTNNB1 (0.50) | CTNNB1KDM4EHPGDALDH1A1IRAK4 | |
| SCHEMBL11583022 | 0.96 | CTNNB1 (0.50) | CTNNB1KDM4EHPGDALDH1A1IRAK4 | |
| SCHEMBL7751522 | 0.82 | CTNNB1 (0.70) | CTNNB1KDM4EHPGDALDH1A1IRAK4 | |
| Potassium Ion SCHEMBL29026645 | 0.81 | CTSD (0.56) | HPGDALDH1A1MAPTHTTHSD17B10 | |
| Potassium Ion SCHEMBL8613654 | 0.81 | KDM4E (0.47) | CTNNB1KDM4EHPGDALDH1A1IRAK4 | |
| Potassium Ion SCHEMBL30903898 | 0.81 | KDM4E (0.47) | CTNNB1KDM4EHPGDALDH1A1IRAK4 | |
| SCHEMBL18340670 | 0.78 | KDM4E (0.54) | CTNNB1KDM4EHPGDALDH1A1IRAK4 | |
| Silver SCHEMBL30782444 | 0.78 | KDM4E (0.48) | CTNNB1KDM4EHPGDALDH1A1IRAK4 | |
| Phthalic Acid SCHEMBL109123 | 0.78 | ALDH1A1 (0.64) | KDM4EHPGDALDH1A1MAPTCYP3A4 | |
| Phthalic Acid SCHEMBL30001010 | 0.78 | ALDH1A1 (0.64) | KDM4EHPGDALDH1A1MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7172854-B2 | Photographic color developer solution and processing method by use thereof | KONICA MINOLTA PHOTO IMAGING, INC. (JP) | 2007-02-06 | — | — | US | disclosed |
| EP-1530081-B1 | Photographic color developer solution and processing method by use thereof | KONICA MINOLTA PHOTO IMAGING (JP) | 2007-01-03 | — | — | EP | disclosed |
| US-20050100834-A1 | Photographic color developer solution and processing method by use thereof | KONICA MINOLTA PHOTO IMAGING, INC. | 2005-05-12 | — | — | US | disclosed |
| EP-1530081-A2 | Photographic color developer solution and processing method by use thereof | Konica Minolta Photo Imaging, Inc. (JP) | 2005-05-11 | — | — | EP | disclosed |