Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | APAF1 | O14727 | 1/20 | 1.00 |
| ▸ | RECQL | P46063 | 1/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | MPO | P05164 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | BLM | P54132 | 1/20 | 0.68 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.68 |
| ▸ | ACE | P12821 | 2/20 | 0.63 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.62 |
| ▸ | HTR1A | P08908 | 1/20 | 0.62 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9880194 | 1.00 | POLB (1.00) | POLBKDM4EMAPTAPAF1RECQL | |
| SCHEMBL9880193 | 1.00 | POLB (1.00) | POLBKDM4EMAPTAPAF1RECQL | |
| SCHEMBL13971370 | 0.88 | POLB (0.78) | POLBKDM4EMAPTAPAF1RECQL | |
| SCHEMBL17326082 | 0.88 | POLB (0.78) | POLBKDM4EMAPTAPAF1RECQL | |
| SCHEMBL9336530 | 0.87 | MAPT (0.76) | POLBKDM4EMAPTAPAF1RECQL | |
| SCHEMBL4666382 | 0.86 | POLB (0.76) | POLBKDM4EMAPTAPAF1RECQL | |
| SCHEMBL8266826 | 0.86 | POLB (0.76) | POLBKDM4EMAPTAPAF1RECQL | |
| SCHEMBL9449541 | 0.85 | SMN1; SMN2 (0.77) | POLBKDM4EMAPTAPAF1RECQL | |
| SCHEMBL20425214 | 0.85 | KDM4E (0.73) | POLBKDM4EMAPTAPAF1RECQL | |
| SCHEMBL20425212 | 0.85 | KDM4E (0.73) | POLBKDM4EMAPTAPAF1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1217884-B1 | METHOD FOR MATURATION OF CONIFER SOMATIC EMBRYOS | WOODY PLANT BIOTECH APS (DK) | 2007-02-21 | — | — | EP | claimed |
| US-6897065-B1 | Method for maturation of conifer somatic embryos | WOODY PLANT BIOTECH APS (DK) | 2005-05-24 | — | — | US | claimed |
| EP-1217884-A1 | METHOD FOR MATURATION OF CONIFER SOMATIC EMBRYOS | Woody Plant Biotech APS (DK) | 2002-07-03 | — | — | EP | claimed |
| WO-2001020972-A1 | METHOD FOR MATURATION OF CONIFER SOMATIC EMBRYOS | WOODY PLANT BIOTECH APS (DK) | 2001-03-29 | — | — | WO | claimed |
| US-20230277454-A1 | NANO-EMULSION OF CBFß-RUNX1 INHIBITOR FOR OCULAR DRUG DELIVER | MASSACHUSETTS EYE AND EAR INFIRMARY | 2023-09-07 | — | — | US | disclosed |
| US-11739326-B2 | RUNX1 inhibition for treatment of proliferative vitreoretinopathy and conditions associated with epithelial to mesenchymal transition | MASSACHUSETTS EYE AND EAR INFIRMARY (US) | 2023-08-29 | — | — | US | disclosed |
| US-20230219888-A1 | PRENYLATED PSILOCYBIN DERIVATIVES AND METHODS OF USING | MAGICMED INDUSTRIES INC. (CA) | 2023-07-13 | — | — | US | disclosed |
| US-11583497-B2 | Nano-emulsion of CBFß-RUNX1 inhibitor for ocular drug delivery | THE SCHEPENS EYE RESEARCH INSTITUTE, INC. (US) | 2023-02-21 | — | — | US | disclosed |
| US-11564971-B2 | Hyaluronic acid derivative having amino acid and steryl group introduced thereinto | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-01-31 | — | — | US | disclosed |
| US-20220184109-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF ABERRANT ANGIOGENESIS | MASSACHUSETTS EYE AND EAR INFIRMARY | 2022-06-16 | — | — | US | disclosed |
| US-20220160849-A1 | CANCER VACCINE FORMULATION | MIE UNIVERSITY (JP) | 2022-05-26 | — | — | US | disclosed |
| US-11229662-B2 | Compositions and methods for the treatment of aberrant angiogenesis | THE SCHEPENS EYE RESEARCH INSTITUTE, INC. (US) | 2022-01-25 | — | — | US | disclosed |
| US-20150191517-A1 | NOVEL SODIUM CHANNEL BLOCKING PEPTIDES AND THE USE THEREOF | PURDUE PHARMA L.P. (US) | 2015-07-09 | — | — | US | disclosed |
| WO-2012066549-A1 | DIPEPTIDE ANALOGS FOR TREATING CONDITIONS ASSOCIATED WITH AMYLOID FIBRIL FORMATION | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2012-05-24 | — | — | WO | disclosed |
| US-20120108529-A1 | PROTEASE INHIBITORS | AMPLYX PHARMACEUTICALS, INC. | 2012-05-03 | — | — | US | disclosed |
| EP-1415986-B1 | SPIRO ISOBENZOFURANES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | BANYU PHARMA CO LTD (JP) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008106619-A2 | INDENOISOQUINOLINONE ANALOGS AND METHODS OF USE THEREOF | INOTEK PHARMACEUTICALS CORPORATION (US) | 2008-09-04 | — | — | WO | disclosed |
| EP-1217884-B1 | METHOD FOR MATURATION OF CONIFER SOMATIC EMBRYOS | WOODY PLANT BIOTECH APS (DK) | 2007-02-21 | — | — | EP | disclosed |
| EP-1217884-A1 | METHOD FOR MATURATION OF CONIFER SOMATIC EMBRYOS | Woody Plant Biotech APS (DK) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001020972-A1 | METHOD FOR MATURATION OF CONIFER SOMATIC EMBRYOS | WOODY PLANT BIOTECH APS (DK) | 2001-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11229662-B2 | Compositions and methods for the treatment of aberrant angiogenesis | VEGFA, PGF, FLT4 | POLB 2595/4885KDM4E 4412/4885MAPT 1642/4885 |
| US-20230219888-A1 | PRENYLATED PSILOCYBIN DERIVATIVES AND METHODS OF USING | AANAT, ACAT2, PCYT1A | POLB 1233/4885KDM4E 3448/4885MAPT 2331/4885 |
| US-20220160849-A1 | CANCER VACCINE FORMULATION | CD44, TP53, MUC1 | POLB 4789/4885KDM4E 2970/4885MAPT 3086/4885 |
| US-11739326-B2 | RUNX1 inhibition for treatment of proliferative vitreoretinopathy and conditions associated with epithelial to mesenchymal transition | RUNX1, CXCL12, MITF | POLB 1058/4885KDM4E 1672/4885MAPT 2925/4885 |
| US-20220184109-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF ABERRANT ANGIOGENESIS | VEGFA, PGF, FLT4 | POLB 2595/4885KDM4E 4412/4885MAPT 1642/4885 |
| US-20120108529-A1 | PROTEASE INHIBITORS | SERPINB1, PREP, DNPEP | POLB 1065/4885KDM4E 858/4885MAPT 1811/4885 |
| US-20150191517-A1 | NOVEL SODIUM CHANNEL BLOCKING PEPTIDES AND THE USE THEREOF | SCN7A, SCN2A, SCN5A | POLB 4536/4885KDM4E 3499/4885MAPT 4023/4885 |
| US-20230277454-A1 | NANO-EMULSION OF CBFß-RUNX1 INHIBITOR FOR OCULAR DRUG DELIVER | RUNX1, CBFB, IKZF1 | POLB 861/4885KDM4E 442/4885MAPT 1318/4885 |
| US-11583497-B2 | Nano-emulsion of CBFß-RUNX1 inhibitor for ocular drug delivery | RUNX1, CBFB, IKZF1 | POLB 907/4885KDM4E 470/4885MAPT 1348/4885 |
| US-11564971-B2 | Hyaluronic acid derivative having amino acid and steryl group introduced thereinto | CD44, DAO, FUT6 | POLB 4801/4885KDM4E 3563/4885MAPT 4444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.