Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | PREP | P48147 | 3/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5160179 | 0.77 | HRH3 (0.35) | SMN1; SMN2CYP11B1CYP11B2ALDH1A1TSHR | |
| SCHEMBL5160189 | 0.72 | FKBP1A (0.46) | HTTPREPACE2CYP3A4ALDH1A1 | |
| SCHEMBL5160862 | 0.72 | CYP11B1 (0.38) | HTTNPC1RAB9ASMN1; SMN2CYP11B1 | |
| SCHEMBL5162622 | 0.69 | HRH3 (0.33) | SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL6174777 | 0.66 | ATM (0.41) | HTTSMN1; SMN2L3MBTL1TDP1 | |
| Hydrochloric Acid SCHEMBL5160752 | 0.65 | HRH3 (0.37) | SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL5161814 | 0.64 | AOC3 (0.39) | — | |
| SCHEMBL23034568 | 0.63 | CYP3A4 (0.47) | CYP1A2CYP3A4ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL5160202 | 0.63 | HTT (0.47) | HTTNPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL26447162 | 0.63 | ALDH1A1 (0.50) | HTTALDH1A1L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070232601-A1 | Vla-4 Inhibitor | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-10-04 | — | — | US | disclosed |
| EP-1757602-A1 | VLA-4 INHIBITOR | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-02-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232601-A1 | Vla-4 Inhibitor | VCAM1, ITGB4, ITGA4 | HTT 3765/4885NPC1 907/4885RAB9A 1194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.