Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | DRD4 | P21917 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14380792 | 0.94 | ALDH1A1 (0.68) | ALDH1A1KDM4ECYP1A2CYP2D6CYP2C19 | |
| SCHEMBL515977 | 0.89 | ALDH1A1 (0.62) | ALDH1A1KDM4ECYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11679951 | 0.87 | CYP2D6 (0.61) | ALDH1A1KDM4ECYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9808080 | 0.87 | ALDH1A1 (0.62) | ALDH1A1KDM4ECYP1A2CYP2D6CYP2C19 | |
| SCHEMBL715500 | 0.84 | LMNA (0.56) | ALDH1A1KDM4ETDP1MAPTKMT2A | |
| SCHEMBL1592876 | 0.84 | TDP1 (0.60) | ALDH1A1KDM4ECYP1A2CYP2D6CYP2C19 | |
| SCHEMBL30327643 | 0.84 | LMNA (0.56) | ALDH1A1KDM4ETDP1MAPTKMT2A | |
| SCHEMBL17997992 | 0.83 | ALDH1A1 (0.65) | ALDH1A1KDM4ECYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9310033 | 0.82 | ALDH1A1 (0.55) | ALDH1A1KDM4ECYP1A2CYP2D6CYP2C19 | |
| SCHEMBL2470447 | 0.82 | ALDH1A1 (0.55) | ALDH1A1KDM4ECYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111465589-B | Compound having fluorene skeleton and method for producing same | 帝人株式会社 | 2024-01-05 | — | — | CN | disclosed |
| US-11339249-B2 | Compound having fluorene skeleton, and method for manufacturing same | TEIJIN LIMITED (JP) | 2022-05-24 | — | — | US | disclosed |
| EP-3747856-A1 | COMPOUND HAVING FLUORENE SKELETON, AND METHOD FOR MANUFACTURING SAME | Teijin Limited (JP) | 2020-12-09 | — | — | EP | disclosed |
| US-20200354517-A1 | COMPOUND HAVING FLUORENE SKELETON, AND METHOD FOR MANUFACTURING SAME | TEIJIN LIMITED (JP) | 2020-11-12 | — | — | US | disclosed |
| CN-111465589-A | Compound having fluorene skeleton and method for producing same | 帝人株式会社 | 2020-07-28 | — | — | CN | disclosed |
| WO-2020085222-A1 | CRYSTAL OF COMPOUND HAVING FLUORENE SKELETON AND METHOD FOR PRODUCING SAME | 帝人株式会社 | 2020-04-30 | — | — | WO | disclosed |
| WO-2019151264-A1 | COMPOUND HAVING FLUORENE SKELETON, AND METHOD FOR MANUFACTURING SAME | 帝人株式会社 | 2019-08-08 | — | — | WO | disclosed |
| US-9670309-B2 | Novolac-based epoxy compound, production method for same, composition and cured article comprising same, and use for same | KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) | 2017-06-06 | — | — | US | disclosed |
| US-20150203626-A1 | NOVOLAC-BASED EPOXY COMPOUND, PRODUCTION METHOD FOR SAME, COMPOSITION AND CURED ARTICLE COMPRISING SAME, AND USE FOR SAME | KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) | 2015-07-23 | — | — | US | disclosed |
| US-8841491-B2 | Method for producing fluorene derivative | TAOKA CHEMICAL CO., LTD. (JP) | 2014-09-23 | — | — | US | disclosed |
| US-20070275987-A1 | Novel pyridopyprimidinone derivatives which are HM74A agonists | HOFFMAN-LA ROCHE INC | 2007-11-29 | — | — | US | disclosed |
| WO-2007134986-A1 | PYRIDOPYRIMIDINONE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2007-11-29 | — | — | WO | disclosed |
| US-5538978-A | NUCLEOSIDE PHOSPHORYLASE INHIBITORS AS IMMUNOSUPPRESSANTS, ANTILYMPHOMA, ANTILEUKEMIA, VIRICIDES AND ANTIPROTOZOA AGENTS | MERRELL PHARMACEUTICALS INC. (US) | 1996-07-23 | — | — | US | disclosed |
| US-5527803-A | IMMUNOSUPPRESSANTS, PHOSPHORYLASE INHIBITORS | MERRELL PHARMACEUTICALS INC. (US) | 1996-06-18 | — | — | US | disclosed |
| US-5494912-A | 9-purinyl phosphonic acid derivitives for treating gout | MERRELL PHARMACEUTICALS INC. (US) | 1996-02-27 | — | — | US | disclosed |
| EP-0465297-B1 | 9-Purinyl phosphonic acid derivatives | MERRELL DOW PHARMA (US) | 1996-01-31 | — | — | EP | disclosed |
| US-5147884-A | Microbiocide mixture containing tert-butyl hydroperoxide, a monophenylglycol ether and a diluent; discoloration inhibition, controlling consistency and preventing odor | STERLING DRUG INC. (US) | 1992-09-15 | — | — | US | disclosed |
| EP-0465297-A1 | 9-Purinyl phosphonic acid derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1992-01-08 | — | — | EP | disclosed |
| US-4148981-A | Dithiophosphorylated copolymers of aziridineethyl acrylates or methacrylates and alkyl acrylates or methacrylates | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1979-04-10 | — | — | US | disclosed |
| US-4136042-A | EXTREME PRESSURE LUBRICANTS | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1979-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200354517-A1 | COMPOUND HAVING FLUORENE SKELETON, AND METHOD FOR MANUFACTURING SAME | RFT1, AFF1, RER1 | ALDH1A1 135/4885KDM4E 2520/4885CYP1A2 382/4885 |
| US-20070275987-A1 | Novel pyridopyprimidinone derivatives which are HM74A agonists | GPR119, HCAR1, GPR84 | ALDH1A1 1422/4885KDM4E 3757/4885CYP1A2 599/4885 |
| US-11339249-B2 | Compound having fluorene skeleton, and method for manufacturing same | RFT1, AFF1, RER1 | ALDH1A1 135/4885KDM4E 2520/4885CYP1A2 382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.