Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 12/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CCKBR | P32239 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7027698 | 0.80 | PRSS1 (0.44) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL5162442 | 0.80 | EGLN1 (0.39) | PPARGPPARA | |
| SCHEMBL5160003 | 0.78 | MGAM (0.44) | MGAMALDH1A1LMNASMN1; SMN2CCKBR | |
| SCHEMBL5160445 | 0.75 | LMNA (0.48) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5162750 | 0.75 | DRD2 (0.50) | ALDH1A1LMNACCKBR | |
| SCHEMBL5160556 | 0.74 | NAAA (0.43) | LMNASMN1; SMN2 | |
| SCHEMBL5158364 | 0.74 | HCAR2 (0.36) | LMNA | |
| SCHEMBL5158724 | 0.74 | LMNA (0.43) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5160652 | 0.73 | GPR84 (0.37) | — | |
| SCHEMBL531061 | 0.73 | TRPV1 (0.49) | MGAMTRPV1CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1340746-B1 | Process for the reduction of 3-heteroaryl-3-oxo-propanoic acid derivatives | SALTIGO GMBH (DE) | 2007-02-28 | — | — | EP | disclosed |
| EP-1340746-A1 | Process for the reduction of 3-heteroaryl-3-oxo-propanoic acid derivatives | BAYER AG (DE) | 2003-09-03 | — | — | EP | disclosed |