Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 4/20 | 0.44 |
| ▸ | CTSG | P08311 | 3/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.44 |
| ▸ | CMA1 | P23946 | 3/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 4/20 | 0.44 |
| ▸ | CES1 | P23141 | 4/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5160556 | 0.87 | NAAA (0.43) | MMP2MMP9MMP12NAAAMAPT | |
| SCHEMBL5160445 | 0.85 | LMNA (0.48) | ALDH1A1MEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL11597057 | 0.83 | CES2 (0.45) | PRSS1CTSGCTRB1CMA1MMP2 | |
| SCHEMBL5158154 | 0.82 | GPR84 (0.34) | PRSS1MMP2MMP9MMP12CNR2 | |
| SCHEMBL5160702 | 0.82 | TRPA1 (0.40) | PRSS1MMP2MMP9MMP12CNR2 | |
| SCHEMBL5158364 | 0.81 | HCAR2 (0.36) | MMP2MMP9MMP12MAPTMAPK1 | |
| SCHEMBL5158724 | 0.81 | LMNA (0.43) | CES2CES1CNR2ALDH1A1KMT2A | |
| SCHEMBL5162412 | 0.80 | MGAM (0.48) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL3033757 | 0.80 | GPR84 (0.52) | MAPTMAPK1 | |
| SCHEMBL11053944 | 0.80 | SLC6A2 (0.48) | PRSS1CTSGCTRB1CMA1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1346977-A1 | Method for producing aryl-aminopropanols | Bayer Aktiengesellschaft (DE) | 2003-09-24 | — | — | EP | claimed |
| EP-1346977-A1 | Method for producing aryl-aminopropanols | Bayer Aktiengesellschaft (DE) | 2003-09-24 | — | — | EP | disclosed |