SCHEMBL516563

SCHEMBL516563

Cc1cccc(OC(C)O)c1

nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.55
ACHE P22303 2/20 0.54
ADRB2 P07550 1/20 0.49
ADRB1 P08588 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.46
TP53 P04637 1/20 0.44
ALDH1A1 P00352 2/20 0.44
KMT2A Q03164 3/20 0.43
MEN1 O00255 2/20 0.43
GAA P10253 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16978755 1.00 LMNA (0.55) LMNAACHEADRB2ADRB1SMN1; SMN2
SCHEMBL30333407 1.00 LMNA (0.55) LMNAACHEADRB2ADRB1SMN1; SMN2
SCHEMBL11138888 0.87 ALDH1A1 (0.59) LMNAACHEADRB2ADRB1ALDH1A1
SCHEMBL2319401 0.87 MTNR1A (0.43) LMNAACHESMN1; SMN2ALDH1A1KMT2A
SCHEMBL8719548 0.84 LMNA (0.52) LMNAACHEADRB2ADRB1SMN1; SMN2
SCHEMBL2557633 0.84 LMNA (0.52) LMNAACHEADRB2ADRB1SMN1; SMN2
SCHEMBL31514931 0.84 LMNA (0.52) LMNAACHEADRB2ADRB1SMN1; SMN2
SCHEMBL12006 0.83 LMNA (0.59) LMNAACHEADRB2ADRB1SMN1; SMN2
SCHEMBL542640 0.83 ACHE (0.58) LMNAACHEADRB2ADRB1SMN1; SMN2
SCHEMBL11150447 0.82 LMNA (0.53) LMNAACHEADRB2ADRB1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115605452-B Polyhydroxy aromatic intermediate, preparation method thereof and application of polyhydroxy aromatic intermediate in polycondensate water reducer containing branched side chains 江苏苏博特新材料股份有限公司 2024-06-11 CN claimed
CN-115260485-B Polycondensate containing multiple adsorption groups, preparation method and application thereof 南京博特新材料有限公司 2024-03-29 CN claimed
WO-2023082175-A1 POLYHYDROXY AROMATIC INTERMEDIATE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF IN POLYCONDENSATE WATER REDUCER CONTAINING BRANCHED SIDE CHAIN 江苏苏博特新材料股份有限公司 2023-05-19 WO claimed
US-20230151140-A1 POLYHYDROXY AROMATIC INTERMEDIATE, PREPARATION THEREOF AND USE THEREOF IN POLYCONDENSATE WATER-REDUCER WITH BRANCHED SIDE CHAINS BOTE NEW MATERIALS TAIZHOU CO., LTD. (CN) 2023-05-18 US claimed
CN-115605452-A Polyhydroxy aromatic intermediate, preparation method thereof and application thereof in polycondensate water reducing agent containing branched side chain 江苏苏博特新材料股份有限公司(CN) 2023-01-13 CN claimed
CN-115260485-A Polycondensate containing multiple adsorption groups as well as preparation method and application thereof 南京博特新材料有限公司 2022-11-01 CN claimed
US-12528907-B2 Polyhydroxy aromatic intermediate, preparation thereof and use thereof in polycondensate water-reducer with branched side chains SOBUTE NEW MATERIALS CO., LTD. (CN) 2026-01-20 US disclosed
CN-115260485-B Polycondensate containing multiple adsorption groups, preparation method and application thereof 南京博特新材料有限公司 2024-03-29 CN disclosed
WO-2023082175-A1 POLYHYDROXY AROMATIC INTERMEDIATE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF IN POLYCONDENSATE WATER REDUCER CONTAINING BRANCHED SIDE CHAIN 江苏苏博特新材料股份有限公司 2023-05-19 WO disclosed
US-20230151140-A1 POLYHYDROXY AROMATIC INTERMEDIATE, PREPARATION THEREOF AND USE THEREOF IN POLYCONDENSATE WATER-REDUCER WITH BRANCHED SIDE CHAINS BOTE NEW MATERIALS TAIZHOU CO., LTD. (CN) 2023-05-18 US disclosed
CN-115605452-A Polyhydroxy aromatic intermediate, preparation method thereof and application thereof in polycondensate water reducing agent containing branched side chain 江苏苏博特新材料股份有限公司(CN) 2023-01-13 CN disclosed
CN-115260485-A Polycondensate containing multiple adsorption groups as well as preparation method and application thereof 南京博特新材料有限公司 2022-11-01 CN disclosed
US-11339249-B2 Compound having fluorene skeleton, and method for manufacturing same TEIJIN LIMITED (JP) 2022-05-24 US disclosed
EP-0391942-A1 PROCESS FOR THE PREPARATION OF ARYLOXYACETIC ACID EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1990-10-17 EP disclosed
US-4935540-A OXIDIZING ARYLOXYETHANOL IN PRESENCE OF PALLADIUM AND THALLIU M ON CARBON CATALYST, ACIDIFYING EASTMAN CHEMICAL COMPANY 1990-06-19 US disclosed
WO-1989003378-A1 PROCESS FOR THE PREPARATION OF ARYLOXYACETIC ACID EASTMAN KODAK COMPANY (US) 1989-04-20 WO disclosed
US-4804777-A OXIDATION OF ARYLOXYETHANOL USING PALLADIUM, SILVER, CARBON CATALYST EASTMAN KODAK COMPANY (US) 1989-02-14 US disclosed
EP-0011793-B1 PROCESS FOR PREPARING ARYLOXYACETIC ACIDS BAYER AG (DE) 1981-09-02 EP disclosed
US-4238625-A ACTIVATORS OF LEAD AND/OR BISMUTH AND/OR THEIR COMPOUNDS FOR OXIDATION WITH PLATINUM OR PALLADIUM CATALYST BAYER AKTIENGESELLSCHAFT (DE) 1980-12-09 US disclosed
EP-0011793-A1 Process for preparing aryloxyacetic acids BAYER AG (DE) 1980-06-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11339249-B2 Compound having fluorene skeleton, and method for manufacturing same RFT1, AFF1, RER1 LMNA 1995/4885ACHE 4254/4885ADRB2 183/4885
US-12528907-B2 Polyhydroxy aromatic intermediate, preparation thereof and use thereof in polycondensate water-reducer with branched side chains IPMK, GRHPR, PIEZO1 LMNA 850/4885ACHE 3379/4885ADRB2 3989/4885
US-20230151140-A1 POLYHYDROXY AROMATIC INTERMEDIATE, PREPARATION THEREOF AND USE THEREOF IN POLYCONDENSATE WATER-REDUCER WITH BRANCHED SIDE CHAINS BICRA, GRHPR, SMARCC2 LMNA 795/4885ACHE 3420/4885ADRB2 3237/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.