Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3202848 | 0.79 | MTNR1A (0.48) | PDE4BPDE4APDE4CPDE4DKDM4E | |
| SCHEMBL20919835 | 0.75 | HTT (0.47) | ALDH1A1HPGDCYP3A4PTGS1PTGS2 | |
| SCHEMBL919252 | 0.71 | KDM4E (0.43) | KDM4EALDH1A1HPGDMTNR1AADRA1A | |
| SCHEMBL3900680 | 0.70 | HTT (0.61) | PDE4BALDH1A1HPGDPTGESHTT | |
| SCHEMBL5166963 | 0.70 | TRPA1 (0.45) | PDE4BPDE4APDE4CPDE4DKDM4E | |
| SCHEMBL919396 | 0.69 | KDM4E (0.39) | KDM4EALDH1A1HPGDMTNR1AGAA | |
| SCHEMBL28479323 | 0.67 | L3MBTL1 (0.51) | KDM4EALDH1A1HPGDMTNR1ATRPA1 | |
| SCHEMBL11552066 | 0.67 | ALDH1A1 (0.52) | KDM4EALDH1A1ADRA2AADRA2BADRA2C | |
| SCHEMBL3897112 | 0.67 | L3MBTL1 (0.43) | KDM4EALDH1A1HPGDMTNR1ATRPA1 | |
| SCHEMBL20588344 | 0.67 | KDM4E (0.33) | KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1768945-A1 | SUBSTITUTED HYDROXYACETOPHENON DERIVATIVES | Riemser Arzneimittel AG (DE) | 2007-04-04 | — | — | EP | disclosed |
| WO-2006003010-A1 | SUBSTITUTED HYDROXYACETOPHENON DERIVATIVES | RIEMSER ARZNEIMITTEL AG (DE) | 2006-01-12 | — | — | WO | disclosed |