Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | TDO2 | P48775 | 2/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9047470 | 0.82 | ALDH1A1 (0.40) | AOC3IDO1TDO2SLC6A2SLC6A4 | |
| SCHEMBL2632859 | 0.80 | ADRA2A (0.47) | AOC3IDO1TDO2CYP17A1SLC6A2 | |
| SCHEMBL8741675 | 0.78 | CHRNA7 (0.41) | IDO1SLC6A2SLC6A3ACHETDP1 | |
| SCHEMBL19493681 | 0.77 | AOC3 (0.42) | AOC3IDO1TDO2SLC6A2SLC6A4 | |
| SCHEMBL8741690 | 0.76 | ESR1 (0.60) | SLC6A2SLC6A3TDP1LMNAALDH1A1 | |
| SCHEMBL8741662 | 0.76 | ADRB2 (0.44) | AOC3IDO1TDO2SLC6A2SLC6A4 | |
| SCHEMBL26869984 | 0.76 | TRPA1 (0.41) | AOC3IDO1TDO2LMNAHTT | |
| SCHEMBL13350443 | 0.76 | ESR1 (0.60) | SLC6A2SLC6A3TDP1LMNAALDH1A1 | |
| SCHEMBL7496948 | 0.76 | SHBG (0.41) | — | |
| SCHEMBL13126150 | 0.75 | CYP17A1 (0.42) | AOC3IDO1TDO2CYP17A1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100415735-C | Amino alcohol derivatives | SANKYO CO (JP) | 2008-09-03 | — | — | CN | disclosed |
| CN-1328387-C | Amino alcohol derivatives | SANKYO CO (JP) | 2007-07-25 | — | — | CN | disclosed |
| EP-1300405-B1 | AMINO ALCOHOL DERIVATIVES | SANKYO CO (JP) | 2007-04-18 | — | — | EP | disclosed |
| CN-1267429-C | Amino alcohol derivatives | SANKYO CO (JP) | 2006-08-02 | — | — | CN | disclosed |
| CN-1800175-A | Amino alcohol derivatives | SANKYO CO (JP) | 2006-07-12 | — | — | CN | disclosed |
| US-6964976-B2 | Amino alcohol derivatives | SANKYO COMPANY, LIMITED (JP) | 2005-11-15 | — | — | US | disclosed |
| CN-1680563-A | Amino alcohol derivatives | SANKYO CO (JP) | 2005-10-12 | — | — | CN | disclosed |
| EP-1471054-A1 | AMINO ALCOHOL DERIVATIVE OR PHOSPHONIC ACID DERIVATIVE AND MEDICINAL COMPOSITION CONTAINING THESE | Sankyo Company, Limited (JP) | 2004-10-27 | — | — | EP | disclosed |
| US-20040132784-A1 | Amino alcohol derivatives | SANKYO COMPANY, LIMITED (JP) | 2004-07-08 | — | — | US | disclosed |
| CN-1494540-A | Amino alcohol derivatives | ������������ʽ���� | 2004-05-05 | — | — | CN | disclosed |
| US-6723745-B2 | PREVENTION OR TREATMENT OF AUTOIMMUNE DISEASE IN WARM BLOODED ANIMAL | SANKYO COMPANY, LIMITED (JP) | 2004-04-20 | — | — | US | disclosed |
| US-20030236297-A1 | Amino alcohol derivatives | SANKYO COMPANY, LIMITED (JP) | 2003-12-25 | — | — | US | disclosed |
| EP-1300405-A1 | AMINO ALCOHOL DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030236297-A1 | Amino alcohol derivatives | CD4, ADH1C, ADH1A | AOC3 702/4885IDO1 59/4885TDO2 2073/4885 |
| US-20040132784-A1 | Amino alcohol derivatives | CD4, ADH1C, ADH1A | AOC3 702/4885IDO1 59/4885TDO2 2073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.