Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 4/20 | 0.46 |
| ▸ | CA1 known ✓ | P00915 | 3/20 | 0.44 |
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.37 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 3/20 | 0.42 |
| ▸ | MMP13 | P45452 | 3/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 2/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2760851 | 0.91 | ZDHHC7 (0.56) | ZDHHC7CA2CA1MMP9MMP13 | |
| SCHEMBL8629278 | 0.91 | ZDHHC7 (0.56) | ZDHHC7CA2CA1MMP9MMP13 | |
| SCHEMBL8028639 | 0.91 | ZDHHC7 (0.56) | ZDHHC7CA2CA1MMP9MMP13 | |
| SCHEMBL8626292 | 0.91 | ZDHHC7 (0.56) | ZDHHC7CA2CA1MMP9MMP13 | |
| SCHEMBL8012303 | 0.91 | ZDHHC7 (0.56) | ZDHHC7CA2CA1MMP9MMP13 | |
| SCHEMBL7853583 | 0.91 | ZDHHC7 (0.56) | ZDHHC7CA2CA1MMP9MMP13 | |
| SCHEMBL8630360 | 0.91 | ZDHHC7 (0.56) | ZDHHC7CA2CA1MMP9MMP13 | |
| SCHEMBL69695 | 0.89 | ZDHHC7 (0.54) | ZDHHC7CA2CA1MMP9MMP13 | |
| SCHEMBL8683345 | 0.89 | ZDHHC7 (0.54) | ZDHHC7CA2CA1MMP9MMP13 | |
| SCHEMBL7199656 | 0.89 | ZDHHC7 (0.54) | ZDHHC7CA2CA1MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070092457-A1 | Compositions comprising polymeric emulsifiers and methods of using the same | JOHNSON & JOHNSON CONSUMER, COMPANIES, INC. | 2007-04-26 | — | — | US | disclosed |
| US-20070092458-A1 | Compositions comprising polymeric emulsifiers and methods of using the same | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. | 2007-04-26 | — | — | US | disclosed |
| EP-1776985-A2 | Compositions comprising polymeric emulsifiers and methods of using the same | Johnson and Johnson Consumer Companies, Inc. (US) | 2007-04-25 | — | — | EP | disclosed |
| EP-1776986-A2 | Sunscreen compositions comprising polymeric emulsifiers and methods of using the same | Johnson and Johnson Consumer Companies, Inc. (US) | 2007-04-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070092458-A1 | Compositions comprising polymeric emulsifiers and methods of using the same | TP53, ERCC1, POLQ | CA2 4244/4885CA1 4706/4885CA12 3494/4885 |
| US-20070092457-A1 | Compositions comprising polymeric emulsifiers and methods of using the same | TP53, ERCC1, POLQ | CA2 4244/4885CA1 4706/4885CA12 3494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.