Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | RARA | P10276 | 3/20 | 0.35 |
| ▸ | RARB | P10826 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL286849 | 0.89 | AKR1C4 (0.45) | DGAT1AKR1C3AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL20076066 | 0.87 | AKR1C3 (0.48) | DGAT1AKR1C3AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL30431884 | 0.87 | AKR1C3 (0.48) | DGAT1AKR1C3AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL22093028 | 0.87 | AKR1C3 (0.39) | DGAT1AKR1C3AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL31470099 | 0.85 | DGAT1 (0.36) | DGAT1AKR1C3AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL30975626 | 0.85 | WDR5 (0.40) | DGAT1AKR1C3AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL516744 | 0.85 | WDR5 (0.40) | DGAT1AKR1C3AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL31392335 | 0.85 | AKR1C3 (0.38) | DGAT1AKR1C3AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL2039681 | 0.85 | KDM4E (0.41) | DGAT1AKR1C3AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL1727042 | 0.85 | CYP3A4 (0.42) | DGAT1AKR1C3AKR1C2AKR1C1AKR1C4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 773 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003670-B | Preparation process of 4-bromo-2, 6-difluorobenzonitrile | 杭州国瑞生物科技有限公司 | 2025-05-30 | — | — | CN | claimed |
| CN-117003670-A | Preparation process of 4-bromo-2, 6-difluorobenzonitrile | 杭州国瑞生物科技有限公司 | 2023-11-07 | — | — | CN | claimed |
| CN-112275319-B | Organic selenium catalyst loaded with carbon nano tubes and preparation method and application thereof | 扬州工业职业技术学院 | 2023-06-06 | — | — | CN | claimed |
| CN-112321396-B | Method for synthesizing hydroquinone through selective oxidation reduction of phenol | 扬州工业职业技术学院 | 2022-05-06 | — | — | CN | claimed |
| CN-113897202-A | Difluoromethyleneoxy liquid crystal compound and synthesis method thereof | 浙江工业大学 | 2022-01-07 | — | — | CN | claimed |
| CN-112321396-A | Method for synthesizing hydroquinone through selective oxidation reduction of phenol | 扬州工业职业技术学院 | 2021-02-05 | — | — | CN | claimed |
| CN-112275319-A | Organic selenium catalyst loaded with carbon nano tube and preparation method and application thereof | 扬州工业职业技术学院 | 2021-01-29 | — | — | CN | claimed |
| CN-108997115-B | Special chiral additive for handwriting board and flexible handwriting film based on same | 合肥微晶材料科技有限公司 | 2021-01-01 | — | — | CN | claimed |
| CN-105859543-A | Method for preparing 2, 6-difluoro-4-bromo-benzoyl chloride | 蚌埠中实化学技术有限公司 | 2016-08-17 | — | — | CN | claimed |
| CN-103058820-A | Preparation methods of 4-bromo-2,6-difluoro-trifluorotoluene and intermediate thereof | LIANHE CHEMICAL TECHNOLOGY CO LTD | 2013-04-24 | — | — | CN | claimed |
| CN-122079899-A | Application of pharmaceutical composition in preparation of medicines for preventing or treating diseases related to Sirttail 7 protein | — | 2026-05-26 | — | — | CN | disclosed |
| US-20260138978-A1 | POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M1 | VANDERBILT UNIV (US) | 2026-05-21 | — | — | US | disclosed |
| EP-4724431-A1 | BENZOFURAN DERIVATIVES AS SIK INHIBITORS AND USE THEREOF | Beone Medicines I GmbH (CH) | 2026-04-15 | — | — | EP | disclosed |
| US-20260098029-A1 | KIF18A INHIBITORS | AMGEN INC. (US) | 2026-04-09 | — | — | US | disclosed |
| US-20260085053-A1 | BENZOFURAN DERIVATIVES AS SIK INHIBITORS AND THE USE THEREOF | BEONE MEDICINES I GMBH (CH) | 2026-03-26 | — | — | US | disclosed |
| US-20050256177-A1 | Phenyl derivatives for the treatment of abnormal cell growth | PFIZER INC | 2005-11-17 | — | — | US | disclosed |
| WO-2005097740-A1 | HISTAMINE H3 RECEPTOR AGENTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2005-10-20 | — | — | WO | disclosed |
| US-20050038104-A1 | Substitute benzothiophene compounds | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2005-02-17 | — | — | US | disclosed |
| WO-2005012283-A1 | SUBSTITUTED BENZOTHIOPHENE COMPOUNDS AND USES THEREOF | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2005-02-10 | — | — | WO | disclosed |
| US-20020049223-A1 | Quinoline and naphthyridine carboxylic acid antibacterials | ABBOTT LABORATORIES | 2002-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260085053-A1 | BENZOFURAN DERIVATIVES AS SIK INHIBITORS AND THE USE THEREOF | SIK1, CHUK, SIK2 | DGAT1 3395/4885AKR1C3 789/4885AKR1C2 907/4885 |
| US-20020049223-A1 | Quinoline and naphthyridine carboxylic acid antibacterials | NQO2, NQO1, NDUFA7 | DGAT1 1579/4885AKR1C3 1053/4885AKR1C2 992/4885 |
| US-20260138978-A1 | POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M1 | CHRM1, CHRM4, CHRM2 | DGAT1 1142/4885AKR1C3 944/4885AKR1C2 1479/4885 |
| US-20260098029-A1 | KIF18A INHIBITORS | KIF18A, KIF18B, KIFC1 | DGAT1 2763/4885AKR1C3 777/4885AKR1C2 540/4885 |
| US-20050038104-A1 | Substitute benzothiophene compounds | TST, SULT1E1, LTC4S | DGAT1 1970/4885AKR1C3 581/4885AKR1C2 1555/4885 |
| US-20050256177-A1 | Phenyl derivatives for the treatment of abnormal cell growth | CCND3, CDC25C, CCNA1 | DGAT1 3486/4885AKR1C3 86/4885AKR1C2 192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.