Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | F7 | P08709 | 3/20 | 0.53 |
| ▸ | F3 | P13726 | 3/20 | 0.53 |
| ▸ | PPARG | P37231 | 3/20 | 0.53 |
| ▸ | FABP3 | P05413 | 3/20 | 0.53 |
| ▸ | PPARD | Q03181 | 2/20 | 0.53 |
| ▸ | PPARA | Q07869 | 2/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.53 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.53 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | FABP4 | P15090 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22063804 | 1.00 | TRPV1 (0.55) | TRPV1ALDH1A1KDM4EF7F3 | |
| SCHEMBL22063420 | 0.98 | TRPV1 (0.53) | TRPV1ALDH1A1KDM4EF7F3 | |
| SCHEMBL518980 | 0.98 | TRPV1 (0.57) | TRPV1ALDH1A1KDM4EF7F3 | |
| SCHEMBL518981 | 0.98 | TRPV1 (0.57) | TRPV1ALDH1A1KDM4EF7F3 | |
| SCHEMBL13966865 | 0.96 | TRPV1 (0.52) | TRPV1ALDH1A1KDM4EF7F3 | |
| SCHEMBL13966868 | 0.94 | TRPV1 (0.50) | TRPV1ALDH1A1KDM4EF7F3 | |
| SCHEMBL26340615 | 0.94 | TRPV1 (0.50) | TRPV1ALDH1A1KDM4EF7F3 | |
| SCHEMBL10521788 | 0.93 | FAAH (0.56) | TRPV1F7F3PPARGPPARD | |
| SCHEMBL517594 | 0.93 | FAAH (0.56) | TRPV1F7F3PPARGPPARD | |
| SCHEMBL518058 | 0.93 | FAAH (0.56) | TRPV1F7F3PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9226925-B1 | Abuse deterrent and anti-dose dumping pharmaceutical salts useful for the treatment of attention deficit/hyperactivity disorder | PISGAH LABORATORIES, INC. (US) | 2016-01-05 | — | — | US | claimed |
| US-8940729-B1 | Abuse deterrent and anti-dose dumping pharmaceutical salts useful for the treatment of attention deficit/hyperactivity disorder | PISGAH LABORATORIES, INC. (US) | 2015-01-27 | — | — | US | claimed |
| US-8912217-B1 | Abuse deterrent and anti-dose dumping pharmaceutical salts useful for the treatment of attention deficit/hyperactivity disorder | PISGAH LABORATORIES, INC. (US) | 2014-12-16 | — | — | US | claimed |
| US-11633365-B2 | Nucleic acid-containing lipid nanoparticle | KYOWA KIRIN CO., LTD. (JP) | 2023-04-25 | — | — | US | disclosed |
| US-11298326-B2 | Nucleic acid-containing lipid nanoparticles | KYOWA KIRIN CO., LTD. (JP) | 2022-04-12 | — | — | US | disclosed |
| US-20200368173-A1 | NUCLEIC ACID-CONTAINING LIPID NANOPARTICLE | KYOWA KIRIN CO., LTD. (JP) | 2020-11-26 | — | — | US | disclosed |
| EP-3662913-A1 | NUCLEIC-ACID-CONTAINING LIPID NANOPARTICLES | Kyowa Kirin Co., Ltd. (JP) | 2020-06-10 | — | — | EP | disclosed |
| US-20180353434-A1 | NUCLEIC ACID-CONTAINING LIPID NANOPARTICLES | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2018-12-13 | — | — | US | disclosed |
| WO-2018062413-A1 | NUCLEIC-ACID-CONTAINING LIPID NANOPARTICLES | 協和発酵キリン株式会社 | 2018-04-05 | — | — | WO | disclosed |
| EP-3275448-A1 | NUCLEIC ACID-CONTAINING LIPID NANOPARTICLES | Kyowa Hakko Kirin Co., Ltd. (JP) | 2018-01-31 | — | — | EP | disclosed |
| US-9226925-B1 | Abuse deterrent and anti-dose dumping pharmaceutical salts useful for the treatment of attention deficit/hyperactivity disorder | PISGAH LABORATORIES, INC. (US) | 2016-01-05 | — | — | US | disclosed |
| US-8912217-B1 | Abuse deterrent and anti-dose dumping pharmaceutical salts useful for the treatment of attention deficit/hyperactivity disorder | PISGAH LABORATORIES, INC. (US) | 2014-12-16 | — | — | US | disclosed |
| US-8846766-B2 | Abuse-deterrent methadone for the safe treatment of drug abuse and pain relief | PISGAH LABORATORIES, INC. (US) | 2014-09-30 | — | — | US | disclosed |
| US-8716337-B1 | Abuse deterrent and anti-dose dumping pharmaceutical salts useful for the treatment of attention deficit/hyperactivity disorder | PISGAH LABORATORIES, INC. (US) | 2014-05-06 | — | — | US | disclosed |
| US-8716278-B1 | Abuse deterrent and anti-dose dumping pharmaceutical salts useful for the treatment of attention deficit/hyperactivity disorder | PISGAH LABORATORIES, INC. (US) | 2014-05-06 | — | — | US | disclosed |
| US-8653065-B1 | Abuse deterrent and anti-dose dumping pharmaceutical salts useful for the treatment of attention deficit/hyperactivity disorder | PISGAH LABORATORIES, INC. (US) | 2014-02-18 | — | — | US | disclosed |
| US-8653106-B2 | Abuse deterrent and anti-dose dumping pharmaceutical salts useful for the treatment of attention deficit/hyperactivity disorder | PISGAH LABORATORIES, INC. (US) | 2014-02-18 | — | — | US | disclosed |
| US-20130338229-A1 | Abuse-Deterrent Methadone for the Safe Treatment of Drug Abuse and Pain Relief | Pisgah National Laboratories, Inc. (US) | 2013-12-19 | — | — | US | disclosed |
| US-8586575-B1 | Abuse deterrent and anti-dose dumping pharmaceutical salts useful for the treatment of attention deficit/hyperactivity disorder | PISGAH LABORATORIES, INC. (US) | 2013-11-19 | — | — | US | disclosed |
| US-20120028960-A1 | ABUSE DETERRENT AND ANTI-DOSE DUMPING PHARMACEUTICAL SALTS USEFUL FOR THE TREATMENT OF ATTENTION DEFICIT/HYPERACTIVITY DISORDER | PISGAH LABORATORIES, INC. | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130338229-A1 | Abuse-Deterrent Methadone for the Safe Treatment of Drug Abuse and Pain Relief | OPRM1, OGFR, OPRK1 | TRPV1 158/4885ALDH1A1 469/4885KDM4E 1146/4885 |
| US-11633365-B2 | Nucleic acid-containing lipid nanoparticle | LIPA, LIPC, PNLIP | TRPV1 3502/4885ALDH1A1 354/4885KDM4E 3193/4885 |
| US-20180353434-A1 | NUCLEIC ACID-CONTAINING LIPID NANOPARTICLES | FASN, ABHD16A, PHAX | TRPV1 2689/4885ALDH1A1 1907/4885KDM4E 2442/4885 |
| US-20120028960-A1 | ABUSE DETERRENT AND ANTI-DOSE DUMPING PHARMACEUTICAL SALTS USEFUL FOR THE TREATMENT OF ATTENTION DEFICIT/HYPERACTIVITY DISORDER | COMT, SLC6A3, SLC6A2 | TRPV1 2915/4885ALDH1A1 235/4885KDM4E 1575/4885 |
| US-11298326-B2 | Nucleic acid-containing lipid nanoparticles | FASN, ABHD16A, PHAX | TRPV1 2689/4885ALDH1A1 1907/4885KDM4E 2442/4885 |
| US-20200368173-A1 | NUCLEIC ACID-CONTAINING LIPID NANOPARTICLE | LIPA, LIPC, PNLIP | TRPV1 3502/4885ALDH1A1 354/4885KDM4E 3193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.